Results 101 to 110 of about 17,110 (255)

Microbes Saving Lives and Reducing Suffering

Microbial Biotechnology, Volume 18, Issue 1, January 2025.
Kenneth Timmis, Zeynep Ceren Karahan, Juan Luis Ramos, Omry Koren, Ana Elena Pérez‐Cobas, Karen Steward, Victor de Lorenzo, Elisabetta Caselli, Margaret Douglas, Clarissa Schwab, Virginia Rivero, Rafael Giraldo, Junkal Garmendia, Raymond J. Turner, Jessamyn Perlmutter, José M. Borrero de Acuña, Pablo Ivan Nikel, Jerome Bonnet, Angela Sessitsch, James K. Timmis, Carla Pruzzo, M. Auxiliadora Prieto, Siavash Isazadeh, Wei E. Huang, Gerard Clarke, Danilo Ercolini, Max Häggblom   +26 more
wiley   +1 more source

Establishment of an in vitro culture system to study the developmental biology of Onchocerca volvulus with implications for anti-Onchocerca drug discovery and screening

, 2021
Narcisse Victor Tchamatchoua Gandjui, Abdel Jélil Njouendou, Eric Njih Gemeg, Fanny Fri Fombad, Manuel Ritter, Chi Anizette Kien, Valerine C. Chunda, Jerome Fru, Mathias Eyong Esum, Marc P. Hübner, Peter Enyong, Achim Hoerauf, Samuel Wanji   +12 more
openalex   +2 more sources

Modelling Neglected Tropical Diseases diagnostics: the sensitivity of skin snips for Onchocerca volvulus in near elimination and surveillance settings. [PDF]

, 2016
BACKGROUND: The African Programme for Onchocerciasis Control has proposed provisional thresholds for the prevalence of microfilariae in humans and of L3 larvae in blackflies, below which mass drug administration (MDA) with ivermectin can be stopped and ...
Attah, Simon K, Basáñez, Maria-Gloria, Bottomley, Christian, Isham, Valerie, Kuesel, Annette C, Lustigman, Sara, Opoku, Nicholas O, Vivas-Martínez, Sarai, Walker, Martin   +8 more
core   +4 more sources

Letter to the Editor: Onchocerca lupi infection [PDF]

, 2015
Paul T. Cantey, Mark Eberhard, Jessica Weeks, Sara Swoboda, Gholamabbas Amin Ostovar   +4 more
openalex   +1 more source

A histochemical study of the Nras/let-60 activity in filarial nematodes [PDF]

, 2015
BACKGROUND: Control and elimination of filarial pathogens is a central focus of major global health efforts directed at parasitic diseases of developing countries.
Charles Mackenzie, James Geary, Maeghan O’Neill, Nicole Madrill, Raquel Lovato, Ron Guderian, Sabine Specht, Samuel Wanji, Timothy Geary   +8 more
core   +1 more source

Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: Relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment [PDF]

, 2020
Raphael Awah Abong, Glory Ngongeh Amambo, Patrick W. Chounna Ndongmo, Abdel Jélil Njouendou, Ritter Manuel, Amuam Andrew Beng, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Fanny Fri Fombad, Theobald Mue Nji, Peter Ivo Enyong, Catherine B. Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde K. S. Carlow, Samuel Wanji   +16 more
openalex   +3 more sources

Orientation of <I>Onchocerca lienalis</I> Stiles (Filarioidea: Onchocercidae) Microfilariae to Black Fly Saliva [PDF]

, 2002
T. Stallings, Mary S. Cupp, E. W. Cupp
openalex   +1 more source

Human filarial Wolbachia lipopeptide directly activates human neutrophils in vitro. [PDF]

, 2014
The host inflammatory response to the Onchocerca volvulus endosymbiont, Wolbachia, is a major contributing factor in the development of chronic pathology in humans (onchocerciasis/river blindness).
Edwards, Steven W, Johnston, Kelly, Tamarozzi, Francesca, Taylor, Mark, Turner, Joseph, Wright, Helen L   +5 more
core   +1 more source

Onchocerciasis Drug Discovery: In Vitro Evaluation of FDA-Approved Drugs against Onchocerca gutturosa in Gambia

Pharmaceutics
Onchocerciasis treatment and control relies mainly on the use of ivermectin which has high activity against the microfilarial stage of Onchocerca volvulus but limited activity against the long-lived, tissue dwelling adult nematodes.
Suzanne Gokool, Simon Townson, Andrew Freeman, Jadzia Siemienski-Kleyn, Jakub Zubrzycki, Senyo Tagboto, Marc P. Hübner, Ivan Scandale   +7 more
doaj   +1 more source

Extracellular Onchocerca-derived small RNAs in host nodules and blood

Parasites & Vectors, 2015
Background microRNAs (miRNAs), a class of short, non-coding RNA can be found in a highly stable, cell-free form in mammalian body fluids. Specific miRNAs are secreted by parasitic nematodes in exosomes and have been detected in the serum of murine and ...
Juan F Quintana, Benjamin L Makepeace, Simon A Babayan, Alasdair Ivens, Kenneth M Pfarr, Mark Blaxter, Alexander Debrah, Samuel Wanji, Henrietta F Ngangyung, Germanus S Bah, Vincent N Tanya, David W Taylor, Achim Hoerauf, Amy H Buck   +13 more
doaj   +1 more source