Results 51 to 60 of about 20,920 (295)

Integrating multiple biomarkers to increase sensitivity for the detection of Onchocerca volvulus infection.

Journal of Infectious Diseases, 2019
Serological assessments for human onchocerciasis are based on IgG4 reactivity against the OV-16 antigen, with sensitivity around 60-80%. We previously identified 7 novel proteins that could enhance onchocerciasis sero-diagnosis.
S. Bennuru, Georgiette Oduro-Boateng, Chinweoke Osigwe, Priscilla Del-Valle, A. Golden, G. Ogawa, V. Cama, S. Lustigman, T. Nutman   +8 more
semanticscholar   +1 more source

First report of filarial nematodes in the genus Onchocerca infecting black flies (Diptera: Simuliidae) in Iran

Scientific Reports, 2023
Black flies are blood-sucking insects of public health importance, and they are effective vectors of pathogens and parasites, such as filarial nematodes of the genus Onchocerca.
Fariba Khanzadeh, Naseh Maleki-Ravasan, Peter H. Adler, Fateh Karimian, Matus Kudela   +4 more
doaj   +1 more source

The Wolbachia Genome of Brugia malayi: Endosymbiont Evolution within a Human Pathogenic Nematode [PDF]

, 2005
Complete genome DNA sequence and analysis is presented for Wolbachia, the obligate alpha-proteobacterial endosymbiont required for fertility and survival of the human filarial parasitic nematode Brugia malayi. Although, quantitatively, the genome is even
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core   +3 more sources

Master of Puppets: How Microbiota Drive the Nematoda Ecology and Evolution?

Ecology and Evolution, Volume 15, Issue 8, August 2025.
The nematode microbiota can influence life‐history traits, thereby shaping the species' ecology and evolutionary trajectories. ABSTRACT In recent decades, the microbiota has emerged as a key driver of biological functions in metazoans, and nematodes are no exception.
Víctor José Trejo‐Meléndez, Jorge Contreras‐Garduño   +1 more
wiley   +1 more source

Phylogenetic relationships of the Wolbachia of nematodes and arthropods [PDF]

, 2006
Wolbachia are well known as bacterial symbionts of arthropods, where they are reproductive parasites, but have also been described from nematode hosts, where the symbiotic interaction has features of mutualism.
Claire Conlon, Edward J Pearce, Julian Parkhill, Katelyn Fenn, Mark Blaxter, Martin Jones, Michael A Quail, Nancy E Holroyd   +7 more
core   +3 more sources

The genome of Onchocerca volvulus, agent of river blindness

Nature Microbiology, 2016
Human onchocerciasis is a serious neglected tropical disease caused by the filarial nematode Onchocerca volvulus that can lead to blindness and chronic disability.
J. Cotton, S. Bennuru, A. Grote, Bhavana Harsha, A. Tracey, R. Beech, S. Doyle, M. Dunn, J. Hotopp, N. Holroyd, T. Kikuchi, Olivia J. Lambert, A. Mhashilkar, P. Mutowo, Nirvana Nursimulu, J. Ribeiro, Matthew B. Rogers, Eleanor Stanley, L. S. Swapna, Isheng. J. Tsai, T. Unnasch, D. Voronin, J. Parkinson, T. Nutman, E. Ghedin, M. Berriman, S. Lustigman   +26 more
semanticscholar   +1 more source

PD‐L2 Inhibits Protective Immunity, Th2 Cell Functional Quality, and GATA‐3 Expression During Filarial Nematode Infection

European Journal of Immunology, Volume 55, Issue 8, August 2025.
During filarial nematode infection with Litomosoides sigmodontis, PD‐L2 down‐regulates Th2 cell expression of GATA‐3 and Th2 cytokines and enables parasite survival. Concurrently, B cells suppress protective immunity through a mechanism that does not involve PD‐L2.
Johanna A. Knipper, Sharon M. Campbell, Judith E. Allen, Matthew D. Taylor   +3 more
wiley   +1 more source

The Mbam drainage system and onchocerciasis transmission post ivermectin mass drug administration (MDA) campaign, Cameroon.

PLoS Neglected Tropical Diseases, 2021
BackgroundThe impact of large scale Mass Drug Adminstration (MDA) of ivermectin on active onchocerciasis transmission by Simulium damnosum, which transmits the parasite O. volvulus is of great importance for onchocerciasis control programmes.
Raphael Awah Abong, Glory Ngongeh Amambo, Ali Ahamat Hamid, Belinda Agbor Enow, Amuam Andrew Beng, Franck Noel Nietcho, Theobald Mue Nji, Abdel Jelil Njouendou, Manuel Ritter, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Fanny Fri Fombad, Peter Ivo Enyong, Catherine Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde Carlow, Samuel Wanji   +18 more
doaj   +1 more source

Ivermectin for onchocercal eye disease (river blindness).

, 2012
BACKGROUND: It is believed that ivermectin (a microfilaricide) could prevent blindness due to onchocerciasis. However, when given to everyone in communities where onchocerciasis is common, the effects of ivermectin on lesions affecting the eye are ...
Ejere, Henry OD, Evans, Jennifer R, Schwartz, Ellen, Wormald, Richard   +3 more
core   +1 more source

The isolation of differentially expressed cDNA clones from the filarial nematode Brugia pahangi [PDF]

, 1999
A cDNA library constructed from 3 day post-infective L3 of the filarial nematode Brugia pahangi was screened by differential hybridization with cDNA probes prepared from different life-cycle stages.
Devaney, E., Hunter, S.J., Martin, S.A., Tetley, L., Thompson, F.J.   +4 more
core   +1 more source