Results 51 to 60 of about 14,002 (264)

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

open access: yesAlzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract Recent years have seen major advances in tau‐associated brain disorders through interdisciplinary research spanning molecular biology, neuroimaging, clinical trials, and therapeutic development. The Tau2024 Global Conference, hosted by the Alzheimer's Association, CurePSP, and Rainwater Charitable Foundation, showcased these efforts by ...
Bess Frost   +42 more
wiley   +1 more source

A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasis

open access: yesParasites & Vectors, 2014
Background New drugs effective against adult filariae (macrofilaricides) would accelerate the elimination of lymphatic filariasis and onchocerciasis. Anti-Onchocerca drug development is hampered by the lack of a facile model. We postulated that SCID mice
Alice Halliday   +13 more
doaj   +1 more source

Onchocerca armillata (Railliet et Henry, 1909) d'un nouvel hôte, Camelus dromedarius

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1976
Onchocerca armillata a été observé dans l'aorte d'un dromadaire, à l'abattoir de Kano, sur les 53 animaux ...
T.W. Schillhorn Van Veen   +2 more
doaj   +1 more source

How can onchocerciasis elimination in Africa be accelerated? Modelling the impact of increased ivermectin treatment frequency and complementary vector control [PDF]

open access: yes, 2017
Background: Great strides have been made toward onchocerciasis elimination by mass drug administration (MDA) of ivermectin. Focusing on MDA-eligible areas, we investigated where the elimination goal can be achieved by 2025 by continuation of current ...
Afework H Tekle   +59 more
core   +3 more sources

Maternal IgE Influence on Fetal and Infant Health

open access: yesImmunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT Immunoglobulin E (IgE) is the most recently discovered and evolved mammalian antibody type, best known for interacting with mast cells (MCs) as immune effectors. IgE‐mediated antigen sensing by MC provides protection from parasites, venomous animals, bacteria, and other insults to barrier tissues exposed to the environment.
Jozef Balla   +2 more
wiley   +1 more source

Genetic and environmental risk factors for dementia in African adults: A systematic review

open access: yesAlzheimer's &Dementia, Volume 21, Issue 4, April 2025.
Abstract Dementia, a leading cause of global mortality, disproportionately impacts sub‐Saharan Africans due to complex genetic and environmental interactions. This systematic review evaluated dementia risk factors among sub‐Saharan Africans, identifying significant genetic and environmental influences using the Preferred Reporting Items for Systematic ...
David Mawutor Donkor   +7 more
wiley   +1 more source

Onchocerca Dewittei Japonica N. Subsp., a common parasite from wild in Kyushu Island, Japan

open access: yesParasite, 2001
We describe Onchocerca dewittei japonica n. subsp. from the Japanese wild boar, Sus scrofa leucomystax, in Oita, Kyushu Island, where all seven animals examined were found to be infected. This study began with efforts to identify the causative species in
Uni S.   +4 more
doaj   +1 more source

Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.

open access: yesPLoS Neglected Tropical Diseases, 2015
Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis.
Christina A Bulman   +24 more
doaj   +1 more source

Australian guidelines for equine internal parasite management

open access: yesAustralian Veterinary Journal, Volume 103, Issue 4, Page 151-158, April 2025.
Over the past few decades, the emergence of resistance amongst intestinal parasites of horses to all available anthelmintic classes has emphasised the need for a paradigm shift in parasite control approaches within the Australian equine industry. Findings of a recent Australia‐wide research project have provided new insights into intestinal parasites ...
A Beasley   +12 more
wiley   +1 more source

Of mice, cattle, and humans: the immunology and treatment of river blindness.

open access: yesPLoS Neglected Tropical Diseases, 2008
River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been hampered by a lack of good animal models, as the parasite
Judith E Allen   +10 more
doaj   +1 more source

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