Results 61 to 70 of about 17,110 (255)

Repurposing auranofin as a lead candidate for treatment of lymphatic filariasis and onchocerciasis.

PLoS Neglected Tropical Diseases, 2015
Two major human diseases caused by filariid nematodes are onchocerciasis, or river blindness, and lymphatic filariasis, which can lead to elephantiasis.
Christina A Bulman, Chelsea M Bidlow, Sara Lustigman, Fidelis Cho-Ngwa, David Williams, Alberto A Rascón, Nancy Tricoche, Moses Samje, Aaron Bell, Brian Suzuki, K C Lim, Nonglak Supakorndej, Prasit Supakorndej, Alan R Wolfe, Giselle M Knudsen, Steven Chen, Chris Wilson, Kean-Hooi Ang, Michelle Arkin, Jiri Gut, Chris Franklin, Chris Marcellino, James H McKerrow, Anjan Debnath, Judy A Sakanari   +24 more
doaj   +1 more source

Human infection with Gongylonema pulchrum [PDF]

, 1994
A 43 year old woman developed a painful tumor at the left buccal mucosa. Following local anti-inflammatory treatment a 35 mm long, living female adult worm of Gongylonema pulchrum was extracted from the affected side.
Jelinek, Thomas, Löscher, Thomas
core  

The Burden of Neglected Tropical Diseases in Rwanda: A Scoping Review

Health Science Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background and Aims Rwanda is among the African countries affected by neglected tropical diseases (NTDs). This scoping review aims to synthesize available information to understand the prevalence, incidence, distribution, morbidity, mortality, and risk factors of NTDs in Rwanda.
Masceline Jenipher Mutsaka‐Makuvaza, Michael Olubusayo Binuyo, Callixte Cyuzuzo, Acsa Igizeneza, Jean Paul Sinumvayo, Oluwaremilekun Grace Ajakaye, Egie Elisha Enabulele, Zororo Chinwadzimba, Ezera Agwu, Nicholas Midzi   +9 more
wiley   +1 more source

Of mice, cattle, and humans: the immunology and treatment of river blindness.

PLoS Neglected Tropical Diseases, 2008
River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been hampered by a lack of good animal models, as the parasite
Judith E Allen, Ohene Adjei, Odile Bain, Achim Hoerauf, Wolfgang H Hoffmann, Benjamin L Makepeace, Hartwig Schulz-Key, Vincent N Tanya, Alexander J Trees, Samuel Wanji, David W Taylor   +10 more
doaj   +1 more source

Complete mitochondrial genome of Onchocerca lupi (Nematoda, Onchocercidae)

Mitochondrial DNA. Part B. Resources, 2021
Onchocerca lupi, Rodonaja 1967, is an emerging, zoonotic filarial nematode parasite that causes ocular disease in dogs, cats, wild canids, and humans. It is the causative agent of ocular onchocercosis in canines with increasing incidence in both North ...
Chandler C. Roe, Jennifer Urbanz, Lela Andrews, Guilherme G. Verocai, David M. Engelthaler, Crystal M. Hepp, Jason W. Sahl   +6 more
doaj   +1 more source

Lords of the flies: dipteran migrants are diverse, abundant and ecologically important

Biological Reviews, Volume 100, Issue 4, Page 1635-1659, August 2025.
ABSTRACT Insect migrants are hugely abundant, with recent studies identifying the megadiverse order Diptera as the major component of many migratory assemblages. Despite this, their migratory behaviour has been widely overlooked in favour of more ‘charismatic’ migrant insects such as butterflies, dragonflies, and moths.
Will L. Hawkes, Myles H.M. Menz, Karl R. Wotton   +2 more
wiley   +1 more source

The astacin metalloprotease moulting enzyme NAS-36 is required for normal cuticle ecdysis in free-living and parasitic nematodes [PDF]

, 2011
Nematodes represent one of the most abundant and species-rich groups of animals on the planet, with parasitic species causing chronic, debilitating infections in both livestock and humans worldwide. The prevalence and success of the nematodes is a direct
ANDREW J. BIRNIE, ANTONY P. PAGE, GILLIAN McCORMACK, GILLIAN STEPEK, Hishida, Page   +5 more
core   +1 more source

The Interconnected World of Dermatology and Ophthalmology

JEADV Clinical Practice, Volume 4, Issue 2, Page 389-399, June 2025.
Medical science, is an integrated field that shares intricate relationship between various organ systems. Similarly, dermatology is inter‐related with various other specialties including ophthalmology. This article depicts the correlation of ophthalmology and dermatology iterating on the genetic diseases, autoimmune diseases, systemic disorders ...
Gyanesh Rathore, Surajit Gorai, Gitikash Purkayastha, Kinnor Das, Prajwal Pudasaini   +4 more
wiley   +1 more source

Evaluation of the in vitro susceptibility of various filarial nematodes to emodepside

International Journal for Parasitology: Drugs and Drug Resistance, 2021
Filariae are vector-borne nematodes responsible for an enormous burden of disease. Human lymphatic filariasis, caused by Wuchereria bancrofti, Brugia malayi, and Brugia timori, and onchocerciasis (caused by Onchocerca volvulus) are neglected parasitic ...
Marc P. Hübner, Simon Townson, Suzanne Gokool, Senyo Tagboto, Mary J. Maclean, Guilherme G. Verocai, Adrian J. Wolstenholme, Stefan J. Frohberger, Achim Hoerauf, Sabine Specht, Ivan Scandale, Achim Harder, Martin Glenschek-Sieberth, Steffen R. Hahnel, Daniel Kulke   +14 more
doaj   +1 more source

Increased expression of a microRNA correlates with anthelmintic resistance in parasitic nematodes [PDF]

, 2017
Resistance to anthelmintic drugs is a major problem in the global fight against parasitic nematodes infecting humans and animals. While previous studies have identified mutations in drug target genes in resistant parasites, changes in the expression ...
Bartley, David, Britton, Collette, Devaney, Eileen, Gillan, Victoria, Gilleard, John S., Gu, Henry, Laing, Roz, Maitland, Kirsty, Marks, Neil D., Martinelli, Axel, Morrison, Alison, Rezansoff, Andrew M., Skuce, Philip J., Winter, Alan D.   +13 more
core   +2 more sources