Results 61 to 70 of about 14,096 (242)

Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs

PLoS Neglected Tropical Diseases, 2018
The genus Onchocerca encompasses parasitic nematodes including Onchocerca volvulus, causative agent of river blindness in humans, and the zoonotic Onchocerca lupi infecting dogs and cats. In dogs, O.
V. Colella, C. Maia, André Pereira, Nuno Goncalves, Marta Caruso, Coralie Martin, L. Cardoso, L. Campino, Ivan Scandale, D. Otranto   +9 more
semanticscholar   +1 more source

The Interconnected World of Dermatology and Ophthalmology

JEADV Clinical Practice, Volume 4, Issue 2, Page 389-399, June 2025.
Medical science, is an integrated field that shares intricate relationship between various organ systems. Similarly, dermatology is inter‐related with various other specialties including ophthalmology. This article depicts the correlation of ophthalmology and dermatology iterating on the genetic diseases, autoimmune diseases, systemic disorders ...
Gyanesh Rathore, Surajit Gorai, Gitikash Purkayastha, Kinnor Das, Prajwal Pudasaini   +4 more
wiley   +1 more source

Of mice, cattle, and humans: the immunology and treatment of river blindness.

PLoS Neglected Tropical Diseases, 2008
River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been hampered by a lack of good animal models, as the parasite
Judith E Allen, Ohene Adjei, Odile Bain, Achim Hoerauf, Wolfgang H Hoffmann, Benjamin L Makepeace, Hartwig Schulz-Key, Vincent N Tanya, Alexander J Trees, Samuel Wanji, David W Taylor   +10 more
doaj   +1 more source

The genome of Onchocerca volvulus, agent of river blindness

Nature Microbiology, 2016
Human onchocerciasis is a serious neglected tropical disease caused by the filarial nematode Onchocerca volvulus that can lead to blindness and chronic disability.
J. Cotton, S. Bennuru, A. Grote, Bhavana Harsha, A. Tracey, R. Beech, S. Doyle, M. Dunn, J. Hotopp, N. Holroyd, T. Kikuchi, Olivia J. Lambert, A. Mhashilkar, P. Mutowo, Nirvana Nursimulu, J. Ribeiro, Matthew B. Rogers, Eleanor Stanley, L. S. Swapna, Isheng. J. Tsai, T. Unnasch, D. Voronin, J. Parkinson, T. Nutman, E. Ghedin, M. Berriman, S. Lustigman   +26 more
semanticscholar   +1 more source

Insights into pathophysiology, biomarkers, and therapeutics in tauopathies: Proceedings of the Tau2024 Global Conference

Alzheimer's &Dementia, Volume 21, Issue 5, May 2025.
Abstract Recent years have seen major advances in tau‐associated brain disorders through interdisciplinary research spanning molecular biology, neuroimaging, clinical trials, and therapeutic development. The Tau2024 Global Conference, hosted by the Alzheimer's Association, CurePSP, and Rainwater Charitable Foundation, showcased these efforts by ...
Bess Frost, James B. Rowe, Rufus O. Akinyemi, Jose F. Abisambra, Nicholas J. Ashton, Matthias Brendel, Luc Buée, David Butler, Maria C. Carrillo, Peter Chung, Claire D. Clelland, Sarah L. DeVos, Kristophe Diaz, Rebecca M. Edelmayer, Fanny M. Elahi, Ratnavalli Ellajosyula, Colin Ewen, Igor Camargo Fontana, Marie‐Christine Galas, Oskar Hansson, Günter Höglinger, Kanta Horie, Agustín Ibanez, Linde Jacobs, Mahmoud B. Maina, Maura Malpetti, Eric McDade, Will McEwan, Laia Montoliu‐Gaya, Catherine J. Mummery, Miranda E. Orr, Jonathan D. Rohrer, Amy Rommel, Carlos Sastre, Tara L. Spires‐Jones, Boon Lead Tee, Tim J. Viney, Jamie M. Walker, Susanne Wegmann, Kristin Wildsmith, Ravi Yadav, Simin Mahinrad, Claire Sexton   +42 more
wiley   +1 more source

Identification of three immunodominant motifs with atypical isotype profile scattered over the Onchocerca volvulus proteome

PLoS Neglected Tropical Diseases, 2017
Understanding the immune response upon infection with the filarial nematode Onchocerca volvulus and the mechanisms that evolved in this parasite to evade immune mediated elimination is essential to expand the toolbox available for diagnostics ...
Ole Lagatie, Bieke van Dorst, L. Stuyver
semanticscholar   +1 more source

Maternal IgE Influence on Fetal and Infant Health

Immunological Reviews, Volume 331, Issue 1, May 2025.
ABSTRACT Immunoglobulin E (IgE) is the most recently discovered and evolved mammalian antibody type, best known for interacting with mast cells (MCs) as immune effectors. IgE‐mediated antigen sensing by MC provides protection from parasites, venomous animals, bacteria, and other insults to barrier tissues exposed to the environment.
Jozef Balla, Abhay P. S. Rathore, Ashley L. St. John   +2 more
wiley   +1 more source

Prevalence and pathological lesions of onchocercosis (Onchocerca fasciata) in camels (Camelus dromedarius) [PDF]

Bulgarian Journal of Veterinary Medicine, 2018
The filarial nematode Onchocerca fasciata lives as an adult worm, forming well developed fibrous tissue nodules within the fascial sheath of various parts of the camel body.
G. Farjanikish, F. Namazi, M. Rajabloo
doaj   +1 more source

Genome-wide analysis of ivermectin response by Onchocerca volvulus reveals that genetic drift and soft selective sweeps contribute to loss of drug sensitivity

bioRxiv, 2016
Background Treatment of onchocerciasis using mass ivermectin administration has reduced morbidity and transmission throughout Africa and Central/South America.
S. Doyle, Catherine Bourguinat, H. Nana-Djeunga, Jonas A Kengne-Ouafo, S. Pion, J. Bopda, J. Kamgno, S. Wanji, H. Che, A. Kuesel, M. Walker, M. Basáñez, D. Boakye, M. Osei-Atweneboana, M. Boussinesq, R. Prichard, W. Grant   +16 more
semanticscholar   +1 more source

Genetic and environmental risk factors for dementia in African adults: A systematic review

Alzheimer's &Dementia, Volume 21, Issue 4, April 2025.
Abstract Dementia, a leading cause of global mortality, disproportionately impacts sub‐Saharan Africans due to complex genetic and environmental interactions. This systematic review evaluated dementia risk factors among sub‐Saharan Africans, identifying significant genetic and environmental influences using the Preferred Reporting Items for Systematic ...
David Mawutor Donkor, Esther Marfo, Ansumana Bockarie, Edward Jenner Tettevi, Maxwell Hubert Antwi, John Dogah, George Nkrumah Osei, David Larbi Simpong   +7 more
wiley   +1 more source