Results 91 to 100 of about 31,479 (242)

Of mice, cattle, and humans: the immunology and treatment of river blindness.

PLoS Neglected Tropical Diseases, 2008
River blindness is a seriously debilitating disease caused by the filarial parasite Onchocerca volvulus, which infects millions in Africa as well as in South and Central America. Research has been hampered by a lack of good animal models, as the parasite
Judith E Allen, Ohene Adjei, Odile Bain, Achim Hoerauf, Wolfgang H Hoffmann, Benjamin L Makepeace, Hartwig Schulz-Key, Vincent N Tanya, Alexander J Trees, Samuel Wanji, David W Taylor   +10 more
doaj   +1 more source

Onchocerca volvulus as a risk factor for developing epilepsy in onchocerciasis endemic regions in the Democratic Republic of Congo: a case control study

Infectious Diseases of Poverty, 2018
BackgroundA high prevalence of epilepsy has been observed in onchocerciasis endemic areas in the Democratic Republic of Congo (DRC). With this study we aimed to investigate whether Onchocerca volvulus infection is a risk factor for developing epilepsy in
M. Mandro, P. Suykerbuyk, F. Tepage, Degratias Rossy, Françoise Ngave, Madina Hasan, A. Hotterbeekx, Germain Mambandu, J. K. Kashama, A. Laudisoit, R. Colebunders   +10 more
semanticscholar   +1 more source

Genetic and environmental risk factors for dementia in African adults: A systematic review

Alzheimer's &Dementia, Volume 21, Issue 4, April 2025.
Abstract Dementia, a leading cause of global mortality, disproportionately impacts sub‐Saharan Africans due to complex genetic and environmental interactions. This systematic review evaluated dementia risk factors among sub‐Saharan Africans, identifying significant genetic and environmental influences using the Preferred Reporting Items for Systematic ...
David Mawutor Donkor, Esther Marfo, Ansumana Bockarie, Edward Jenner Tettevi, Maxwell Hubert Antwi, John Dogah, George Nkrumah Osei, David Larbi Simpong   +7 more
wiley   +1 more source

Analysis of age-dependent trends in Ov16 IgG4 seroprevalence to onchocerciasis [PDF]

, 2016
BACKGROUND: Diagnostics provide a means to measure progress toward disease elimination. Many countries in Africa are approaching elimination of onchocerciasis after successful implementation of mass drug administration programs as well as vector control.
Adade, Kangi, Banla, Meba, de los Santos, Tala, Domingo, Gonzalo J, Faulx, Dunia, Gantin, Richard G, Golden, Allison, Kalnoky, Michael, Karabou, Potochoziou, Komlan, Kossi, Peck, Roger, Rao, Ramakrishna, Soboslay, Peter T, Stevens, Eric, Yokobe, Lindsay   +14 more
core   +2 more sources

Spatial and temporal diversity of Simulium damnosum s.l. gut microbiota and association with Onchocerca volvulus infection in Cameroon

International Journal of Infectious Diseases
Introduction: The arthropod microbiota plays a crucial role in host physiology, from the complementation of certain metabolic pathways to the bioecological adaptation of vectors.
Mr Arnauld Ekangouo, Dr Hugues Nana-Djeunga, Dr Philippe Nwane, Dr Guilhem Sempere, Prof Joseph Kamgno, Dr Anne Gieger   +5 more
doaj   +1 more source

Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-Saharan Africa.

PLoS Neglected Tropical Diseases, 2014
BackgroundEpilepsy is common in developing countries, and it is often associated with parasitic infections. We investigated the relationship between exposure to parasitic infections, particularly multiple infections and active convulsive epilepsy (ACE ...
Gathoni Kamuyu, Christian Bottomley, James Mageto, Brett Lowe, Patricia P Wilkins, John C Noh, Thomas B Nutman, Anthony K Ngugi, Rachael Odhiambo, Ryan G Wagner, Angelina Kakooza-Mwesige, Seth Owusu-Agyei, Kenneth Ae-Ngibise, Honorati Masanja, Faith H A Osier, Peter Odermatt, Charles R Newton, Study of Epidemiology of Epilepsy in Demographic Sites (SEEDS) group   +17 more
doaj   +1 more source

Assessment of multiplex Onchocerca volvulus peptide ELISA in non-endemic tropical regions

Parasites & Vectors, 2019
Currently, serodiagnosis of infection with the helminth parasite Onchocerca volvulus is limited to the Ov-16 IgG4 test, a test that has limited sensitivity and suboptimal specificity.
Ole Lagatie, Elodie Granjon, M. Odiere, M. Zrein, L. Stuyver   +4 more
semanticscholar   +1 more source

Community‐based epilepsy care in an onchocerciasis‐endemic area: A 3‐year cohort study in Mahenge, Tanzania

Epilepsia, Volume 66, Issue 3, Page 739-752, March 2025.
Abstract Objective In onchocerciasis‐endemic areas, limited access to antiseizure medications (ASMs) contributes to a high epilepsy burden. This study evaluated the impact of a community‐based epilepsy care program in Mahenge, Tanzania, an onchocerciasis‐endemic area with high epilepsy prevalence.
Dan Bhwana, Luís‐Jorge Amaral, Olivia Kamoen, Athanas Mhina, Vivian Mushi, William Makunde, William Matuja, Meshack Mpogole, Bruno P. Mmbando, Robert Colebunders   +9 more
wiley   +1 more source

Human infection with Gongylonema pulchrum [PDF]

, 1994
A 43 year old woman developed a painful tumor at the left buccal mucosa. Following local anti-inflammatory treatment a 35 mm long, living female adult worm of Gongylonema pulchrum was extracted from the affected side.
Jelinek, Thomas, Löscher, Thomas
core  

Mansonella perstans, Onchocerca volvulus and Strongyloides stercoralis infections in rural populations in central and southern Togo

Parasite Epidemiology and Control, 2018
Background: Mansonella perstans, Onchocerca volvulus and Strongyloides stercoralis are widespread helminth parasites in the tropics. Their distribution remains difficult to determine as it may change during national disease control programs and with ...
Francois Korbmacher, Kossi Komlan, Richard G. Gantin, Wiyao P. Poutouli, Koffi Padjoudoum, Potchoziou Karabou, Peter T. Soboslay, Carsten Köhler   +7 more
doaj   +1 more source