Results 91 to 100 of about 13,344 (260)
Adrenocortical, autonomic, and inflammatory causes of the metabolic syndrome: nested case-control study. [PDF]
, 2002 BACKGROUND: The causes of metabolic syndrome (MS), which may be a precursor of coronary disease, are uncertain. We hypothesize that disturbances in neuroendocrine and cardiac autonomic activity (CAA) contribute to development of MS.Andrew, R, Brunner, EJ, Checkley, S, Clarke, P, Hemingway, H, Juneja, M, Kumari, M, Lowe, GDO, Marmot, MG, Page, M, Papadopoulos, A, Rumley, A, Seckl, JR, Shipley, MJ, Stansfeld, SA, Walker, BR +15 morecore +1 more sourceNeglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms
Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.Moses Agbomhere Hamed, Olabanji Ahmed Surakat, Victor Olukayode Ekundina, Kabirat Bolajoko Jimoh, Adetomiwa Ezekiel Adeogun, Nafisat Omolola Akanji, Oluwafemi Joshua Babalola, Patrick Chukwunonso Eya, Rajib Chowdhury +8 morewiley +1 more sourceAnalysis of age-dependent trends in Ov16 IgG4 seroprevalence to onchocerciasis [PDF]
, 2016 BACKGROUND: Diagnostics provide a means to measure progress toward disease elimination. Many countries in Africa are approaching elimination of onchocerciasis after successful implementation of mass drug administration programs as well as vector control. Adade, Kangi, Banla, Meba, de los Santos, Tala, Domingo, Gonzalo J, Faulx, Dunia, Gantin, Richard G, Golden, Allison, Kalnoky, Michael, Karabou, Potochoziou, Komlan, Kossi, Peck, Roger, Rao, Ramakrishna, Soboslay, Peter T, Stevens, Eric, Yokobe, Lindsay +14 morecore +2 more sourcesOnchocerciasis transmission in Ghana: biting and parous rates of host-seeking sibling species of the Simulium damnosum complex [PDF]
, 2014 Background:
Ghana is renowned for its sibling species diversity of the Simulium damnosum complex, vectors of Onchocerca volvulus. Detailed entomological knowledge becomes a priority as onchocerciasis control policy has shifted from morbidity reduction A Renz, AG Guevara, Anthony Tetteh-Kumah, AP Plaisier, AP Plaisier, AP Plaisier, B Adewale, B Philippon, CG Vajime, CJ Clopper, CR Katholi, D Quillévéré, D Quillévéré, Daniel A Boakye, DB Blacklock, DC Kurtak, DJ Lewis, E Soumbey-Alley, ES Alley, HC Turner, HC Turner, HC Turner, HP Duerr, HP Duerr, Iñaki Tirados, J Grunewald, J Remme, JAN Filipe, JB Davies, JB Rayaisse, JC Vieira, JF Walsh, JR Davis, K Gustavsen, L Yaméogo, M Demanou, M Winnen, MA Adeleke, MA Rodríguez-Pérez, MA Rodríguez-Pérez, Martin Walker, María-Gloria Basáñez, MD Achukwi, MD Wilson, MD Wilson, ME Grillet, ME Grillet, MG Basáñez, MG Basáñez, MG Basáñez, Michael D Wilson, Mike Y Osei-Atweneboana, MO Omolo, P McCullagh, Peter Winskill, PH Adler, PJ Ham, Poppy HL Lamberton, PT Dang, R Garms, R Garms, R Garms, R Garms, R Garms, R Garms, R Le Berre, R Le Berre, R Mank, RA Cheke, RA Cheke, RA Cheke, RA Cheke, RA Cheke, RA Cheke, RA Cheke, RJ Post, RJ Post, Robert A Cheke, Rory J Post, RW Crosskey, RW Dunbar, S Dugassa, SE Meredith, SJ Torr +83 morecore +4 more sourcesZoonotic onchocerciasis caused by a parasite from wild boar in Oita, Japan
Parasite, 2004 Histological examination of a nodule removed from the back of the hand of a 58-year-old woman from Oita, Kyushu, Japan showed an Onchocerca female sectioned through the posterior region of the worm (ovaries identifiable) and young (thin cuticle).Takaoka H., Bain O., Uni S., Korenaga M., Kozek W.J., Shirasaka C., Aoki C., Otsuka Y., Fukuda M., Eshita Y., Daa T. +10 moredoaj +1 more sourceStructures of Trichomonas vaginalis macrophage migratory inhibitory factor
Acta Crystallographica Section F, Volume 80, Issue 12, Page 341-347, December 2024.The production, crystallization and three crystal structures of macrophage migratory inhibitory factor from T. vaginalis are reported.The unicellular parasitic protozoan Trichomonas vaginalis causes trichomoniasis, the most prevalent nonviral sexually transmitted disease globally. T.Aruesha Srivastava, Aryana Nair, Omolara C. O. Dawson, Raymond Gao, Lijun Liu, Justin K. Craig, Kevin P. Battaile, Elizabeth K. Harmon, Lynn K. Barrett, Wesley C. Van Voorhis, Sandhya Subramanian, Peter J. Myler, Scott Lovell, Oluwatoyin A. Asojo, Rabih Darwiche +14 morewiley +1 more sourceEntomological surveillance of onchocerciasis in Burkina Faso: Progress towards interrupting transmission in blackflies in the main river basins of the country
Current Research in Parasitology and Vector-Borne DiseasesCurrent guidelines for onchocerciasis elimination rely heavily upon assessment of the presence of Onchocerca volvulus in the vector Simulium damnosum (sensu lato).Lassane Koala, Achille S. Nikièma, Mathias Ouedraogo, Justin Compaoré, Clarisse Bougouma, Karim Sanon, Aimé G. Adjami, Moussa S. Sanfo, Inaki Tirados, Philip McCall, Paul Bessel, Thomas R. Unnasch, Daniel A. Boakye, Soungalo Traore, Roch K. Dabire +14 moredoaj +1 more sourceA Phase 1, Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of AWZ1066S, an Anti‐Wolbachia Candidate Macrofilaricide
Clinical Pharmacology in Drug Development, Volume 13, Issue 9, Page 1071-1081, September 2024.Abstract
AWZ1066S has been developed as a potential treatment for the neglected tropical diseases lymphatic filariasis and onchocerciasis. AWZ1066S targets the Wolbachia bacterial endosymbiont present in the causative nematode parasites. This phase 1, first‐in‐human study aimed to assess the safety and pharmacokinetics of AWZ1066S in healthy human ...Graham Devereux, Marcin Bula, Karen Tripp, Richard Fitzgerald, Nicola Eraut, Muhammad Salman Alam, Tomoyuki Moriyama, Raku Shinkyo, Lauren Walker, Duolao Wang, Fabian Gusovsky, Jeannette van der Velde, Joseph D. Turner, Weiqian David Hong, Paul M. O'Neill, Mark J. Taylor, Stephen A. Ward +16 morewiley +1 more sourceMorphological and molecular characterization of Onchocerca fasciata (Nematoda, Onchocercidae) from dromedary camels (Camelus dromedarius) in Iran
Parasite, 2018 Skin nodules of Onchocerca fasciata Railliet and Henry, 1910 (Spirurida, Onchocercidae) are a common finding in dromedary camels, though with a minimal clinical impact.Mirzaei Mohammad, Ghahvei Younes, Lefoulon Emilie, Lia Riccardo Paolo, Otranto Domenico, Martin Coralie, Sazmand Alireza +6 moredoaj +1 more sourceDifferential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: Relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment [PDF]
, 2020 Raphael Awah Abong, Glory Ngongeh Amambo, Patrick W. Chounna Ndongmo, Abdel Jélil Njouendou, Ritter Manuel, Amuam Andrew Beng, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Fanny Fri Fombad, Theobald Mue Nji, Peter Ivo Enyong, Catherine B. Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde K. S. Carlow, Samuel Wanji +16 moreopenalex +3 more sources