Results 131 to 140 of about 31,479 (242)

The kunitz domain protein BLI-5 plays a functionally conserved role in cuticle formation in a diverse range of nematodes [PDF]

, 2010
The cuticle of parasitic nematodes performs many critical functions and is essential for proper development and for protection from the host immune response.
Antony P. Page, Bernard, Blaxter, Chu, Cook, Fessler, Ford, Frand, Ghedin, Gillian McCormack, Gillian Stepek, Hawdon, Johnstone, Johnstone, Kingston, Kingston, Kramerova, Kramerova, Kress, Mieszczanek, Milstone, Nagano, Novelli, Novelli, Paesen, Page, Page, Poole, Priess, Redmond, Rhoads, Sasaki, Scott, Shamansky, Skuce, Stanssens, Studier, Thacker, Thacker, Thacker, Thacker, Thein, Wells, Winter   +43 more
core   +1 more source

A Recombinant Positive Control for Serology Diagnostic Tests Supporting Elimination of Onchocerca volvulus

PLoS Neglected Tropical Diseases, 2016
Background Serological assays for human IgG4 to the Onchocerca volvulus antigen Ov16 have been used to confirm elimination of onchocerciasis in much of the Americas and parts of Africa.
A. Golden, Eric Stevens, L. Yokobe, D. Faulx, M. Kalnoky, R. Peck, Melissa Valdez, C. Steel, Potochoziou K. Karabou, M. Banla, P. Soboslay, Kangi Adade, A. Tekle, V. Cama, Peter U. Fischer, T. Nutman, T. Unnasch, T. de Los Santos, G. Domingo   +18 more
semanticscholar   +1 more source

Simuliidae (Diptera, Culicomorpha) no Brasil - XII sobre o gênero Thyrsopelma Enderlein, 1934: descrição de T. jeteri Sp.N., considerações sobre o cibário e chave para as pupas Brazilian Simuliidae (Diptera, Culicomorpha) - XII about the genus Thyrsopelma Enderlein, 1934: description of the T. jeteri new species, considerations related with cibarium and key for the pupae

Acta Amazonica, 2005
É acrescentado um novo caráter pupal para a espécie T. hirtipupa (Lutz,1910). É evidenciada a existência de dentes no cibário da fêmea de T. guianense (Wise,1911), principal espécie envolvida na transmissão da filaria Onchocerca volvulus (Leuckart,1893 ...
Victor PY-Daniel, Sandra Magni Darwich, Lúcia Beatriz Mardini, Milton Norberto Strieder, Sixto Coscarón   +4 more
doaj   +1 more source

Evaluation of the diagnostic potential of urinary N-Acetyltyramine-O,β-glucuronide (NATOG) as diagnostic biomarker for Onchocerca volvulus infection

Parasites & Vectors, 2016
Onchocerciasis, also known as river blindness is one of the neglected tropical diseases affecting millions of people, mainly in sub-Saharan Africa and is caused by the filarial nematode Onchocerca volvulus.
Ole Lagatie, E. Njumbe Ediage, Linda Batsa Debrah, L. Diels, C. Nolten, Petra Vinken, A. Debrah, L. Dillen, S. Silber, L. Stuyver   +9 more
semanticscholar   +1 more source

Model-Based Geostatistical Mapping of the Prevalence of Onchocerca volvulus in West Africa

PLoS Neglected Tropical Diseases, 2016
Background The initial endemicity (pre-control prevalence) of onchocerciasis has been shown to be an important determinant of the feasibility of elimination by mass ivermectin distribution.
S. O'Hanlon, Hannah C. Slater, R. Cheke, B. Boatin, L. Coffeng, S. Pion, M. Boussinesq, Honorat G M Zoure, W. Stolk, M. Basáñez   +9 more
semanticscholar   +1 more source

Characterizing Reactivity to Onchocerca volvulus Antigens in Multiplex Bead Assays.

American Journal of Tropical Medicine and Hygiene, 2017
Multiplex bead assays (MBAs) may provide a powerful integrated tool for monitoring, evaluation, and post-elimination surveillance of onchocerciasis and co-endemic diseases; however, the specificity and sensitivity of Onchocerca volvulus antigens have not
Karla Feeser, V. Cama, J. Priest, E. Thiele, R. Wiegand, T. Lakwo, S. Feleke, P. Cantey   +7 more
semanticscholar   +1 more source

Density-dependent processes in the transmission of human onchocerciasis: relationship between the numbers of microfilariae ingested and successful larval development in the simuliid vector [PDF]

, 2017
A previous paper reported that the intake of Onchocerca volvulus microfilariae (mff) by different species of Simulium is essentially proportional to the parasite load in the skin of infected carriers.
Alley, E. S., Anderson, R. M., Bain, O., Basáñez, M. G., Medley, G. F., Remme, J. H. F., Shelley, A. J.   +6 more
core  

Differential susceptibility of Onchocerca volvulus microfilaria to ivermectin in two areas of contrasting history of mass drug administration in Cameroon: Relevance of microscopy and molecular techniques for the monitoring of skin microfilarial repopulation within six months of direct observed treatment [PDF]

, 2020
Raphael Awah Abong, Glory Ngongeh Amambo, Patrick W. Chounna Ndongmo, Abdel Jélil Njouendou, Ritter Manuel, Amuam Andrew Beng, Mathias Eyong Esum, Kebede Deribe, Jerome Fru Cho, Fanny Fri Fombad, Theobald Mue Nji, Peter Ivo Enyong, Catherine B. Poole, Kenneth Pfarr, Achim Hoerauf, Clotilde K. S. Carlow, Samuel Wanji   +16 more
openalex   +1 more source

A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes [PDF]

, 2014
Myristoylation is a lipid modification involving the addition of a 14-carbon unsaturated fatty acid, myristic acid, to the N-terminal glycine of a subset of proteins, a modification that promotes their binding to cell membranes for varied biological ...
Carlow, Clotilde K. S., Chapman, Melissa S., Galvin, Brendan D., Li, Zhiru, Pollastri, Michael P., Poole, Catherine B., Villemaine, Estelle, Wyatt, Paul G.   +7 more
core   +4 more sources

Irreversible Effects of Ivermectin on Adult Parasites in Onchocerciasis Patients in the Onchocerciasis Control Programme in West Africa [PDF]

, 2017
Ivermectin is an effective drug for the treatment of human onchocerciasis, a disease caused by the parasitic filarial nematode Onchocerca volvulus.
Alley, E. Soumbey, Boatin, Boakye A., Bonneux, Luc, De Vias, Sake J., Habbema, J. Dik F., Plaisier, Anton P., Remme, Hans, Van Oortmarssen, Gerrit J.   +7 more
core