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Intracytoplasmic Bacteria in Onchocerca Volvulus
The American Journal of Tropical Medicine and Hygiene, 1977Ultrastructural studies on Onchocerca volvulus disclosed intracellular organisms within the lateral chords of adult worms and of the larval stages. In the females the organisms were also present in the oogonia, oocytes, developing eggs and microfilariae.
W J, Kozek, H F, Marroquin
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The actin genes of Onchocerca volvulus
Molecular and Biochemical Parasitology, 1992The genome of Onchocerca volvulus was found to contain 2 actin gene classes (called 1 and 2) of 2 genes each. The 4 genes are located in 2 clusters (called A and B), each containing a gene class member. Five short introns of 122-207 bp occur within each gene.
W, Zeng, J E, Donelson
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Immunohistological studies on Onchocerca volvulus paramyosin
Parasitology Research, 2009Paramyosin is a muscular protein exclusively found in invertebrate species, which has been proposed as a vaccine candidate against infections with Schistosoma mansoni and Brugia malayi. Here, we report the studies on the distribution of Onchocerca volvulus paramyosin, designated OvPmy, in different O.
Klaus D, Erttmann, Dietrich W, Büttner
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Morphology ofOnchocerca volvulus
American Journal of Clinical Pathology, 1972Onchocercal nodules from 18 Africans were studied. Each nodule contained adult worms of Onchocerca volvulus . Male and female worms were reconstructed from serial paraffin sections, and the morphologic features of the adult worms and microfilariae described.
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Chitin in egg shells of Onchocerca gibsoni and Onchocerca volvulus
Molecular and Biochemical Parasitology, 1987Chemical analysis of adult females of Onchocerca gibsoni gave estimated chitin contents of 200-500 micrograms (g dry weight)-1. Egg shells from both O. gibsoni and Onchocerca volvulus stained with Calcofluor white and with fluorescent wheat germ agglutinin as shown by fluorescent light microscopy, and bound gold-labelled wheat germ agglutinin as shown ...
L J, Brydon +3 more
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Characterization of an Onchocerca-Specific DNA Clone from Onchocerca Volvulus
The American Society of Tropical Medicine and Hygiene, 1987A genomic library of a savanna isolate of Onchocerca volvulus was screened to detect recombinant plasm ids containing highly repeated DNA sequences of this parasite. Four recombinant plasmids were identified which hybridized specifically to Onchocerca DNA, but not to DNA from humans, black flies, Brugia malayi, B. pahangi, or Wuchereria bancrofti.
J S, Shah +3 more
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Onchocerca volvulus, Wolbachia and River Blindness
2007Chronic infection with filarial nematodes results in development of a suppressive response to an immense parasite burden, thereby limiting pathological and clinical manifestations. However, pro-inflammatory responses to dead and degenerating Onchocerca volvulus worms and release of endosymbiotic Wolbachia bacteria result in corneal opacification ...
Eric, Pearlman +1 more
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Onchocerca volvulus (Leuckart 1893)
1995Onchocerca volvulus is a filarial nematode living in the subcutaneous tissues. Humans are its only host. The vector of O. volvulus is the black-fly Simulium sp. (see Chap. 38). O. volvulus is prevalent in Africa and Latin America. The greatest pathology, however, occurs in an equatorial belt extending across sub-Saharan Africa, where onchocerciasis is ...
Dickson D. Despommier +2 more
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The γ-glutamylcysteine synthetase of Onchocerca volvulus
Molecular and Biochemical Parasitology, 2000The tripeptide glutathione (GSH) plays an important role in the maintenance of the intracellular thiol redox state and in detoxification processes. The intracellular GSH level depends on glutathione reductase as well as on GSH synthesis. The first and rate limiting step in the synthetic pathway is catalysed by gamma-glutamylcysteine synthetase (gamma ...
K, Lüersen +4 more
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DNA-based detection of Onchocerca volvulus
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2002During the 1980s, the idea of using deoxyribonucleic acid probes for specific identification and diagnosis of infectious agents became very fashionable. There was therefore an explosion in the development of these tools and one particular group of organisms which received much attention was the parasitic nematodes.
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