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The Effects of Ivermectin on Transmission of Onchocerca volvulus
Science, 1986Ivermectin, given to onchocerciasis patients as a single oral dose of 200 micrograms per kilogram of body weight, substantially reduced the uptake of Onchocerca volvulus microfilariae by Simulium yahense , an efficient black fly vector of the parasite in the tropical rain forests of West ...
BM Greene +6 more
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DNA-based detection of Onchocerca volvulus
Transactions of the Royal Society of Tropical Medicine and Hygiene, 2002During the 1980s, the idea of using deoxyribonucleic acid probes for specific identification and diagnosis of infectious agents became very fashionable. There was therefore an explosion in the development of these tools and one particular group of organisms which received much attention was the parasitic nematodes.
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The Cryopreservation and in Vitro Cultivation of Larval Onchocerca Volvulus
The American Journal of Tropical Medicine and Hygiene, 1979A system developed in our laboratory for the in vitro cultivation of larval Onchocerca volvulus is being employed in a series of morphogenetic, physiologic, chemotherapeutic and immunologic investigations of this parasite. Because of the need for a large and readily available supply of living worms for this work, cryogenic techniques are being used for
Figueroa Marroquín H +3 more
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Ascaris suum and Onchocerca volvulus: S-adenosylmethionine decarboxylase
Experimental Parasitology, 1988Putrescine-dependent S-adenosylmethionine decarboxylase (EC 4.1.1.50) was demonstrated in Ascaris suum and Onchocerca volvulus; activation was found to be about fourfold by putrescine. Mg2+ did not affect the enzyme activity. A. suum was taken as a model nematode and its S-adenosylmethionine decarboxylase was partially purified and characterized.
Sushma Rathaur +2 more
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Onchocerca volvulus (Leuckart 1893)
1995Onchocerca volvulus is a filarial nematode living in the subcutaneous tissues. Humans are its only host. The vector of O. volvulus is the black-fly Simulium sp. (see Chap. 38). O. volvulus is prevalent in Africa and Latin America. The greatest pathology, however, occurs in an equatorial belt extending across sub-Saharan Africa, where onchocerciasis is ...
Dickson D. Despommier +2 more
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The Association of Adult Onchocerca volvulus with Lymphatic Vessels
Journal of Parasitology, 2010Immunocytochemical examination of onchocercal nodule tissues containing adult Onchocerca volvulus using immuno-markers for blood and lymphatic vessels (vWF, D2-40, podoplanin, Prox-1, and Lyve1) shows a distinct pattern of distribution of these vessels within nodules.
Timothy G. Geary +5 more
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Observations on adult Onchocerca volvulus maintained in vitro
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1984Adult Onchocerca volvulus were enzymatically isolated with collagenase from excised nodules and kept in TC medium 199 with Hank's salts supplemented with various sera. Male and female worms survived in the culture medium and 10% human serum on average for about 11 days (maximum 28 days) and 14.5 days (maximum 42 days).
F. Engelbrecht, H. Schulz-Key
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Fine Structure of the Cuticle of Female Onchocerca volvulus
The Journal of Parasitology, 1974The fine structure of the cuticle of adult female Onchocerca volvulus, a tissue-dwelling nematode parasite of man, was studied. Although the cuticle is composed of the 3 layers characteristic of nematodes (cortex, matrix, and fiber), there were also unusual features.
Francisco J. Aguilar +2 more
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2009
Parasite-vector interactions shape the population dynamics of vector-borne infections and contribute to observed epidemiological patterns. Also, parasites and their vectors may co-evolve, giving rise to locally adapted combinations or complexes with the potential to stabilise the infection.
Thomas S. Churcher +3 more
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Parasite-vector interactions shape the population dynamics of vector-borne infections and contribute to observed epidemiological patterns. Also, parasites and their vectors may co-evolve, giving rise to locally adapted combinations or complexes with the potential to stabilise the infection.
Thomas S. Churcher +3 more
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Periodic reproduction of onchocerca volvulus
Parasitology Today, 1986H. Schulz-Key, M. Karam
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