Results 91 to 100 of about 18,093 (248)

Barriers to the National Onchocerciasis Control Programme at operational level in Cameroon: a qualitative assessment of stakeholders’ views

Parasites & Vectors, 2019
Background The global burden of onchocerciasis is the heaviest in sub-Saharan Africa. Studies have shown the importance of the role of Community-Directed Distributors (CDDs) and nurses in onchocerciasis control, but little is known about their experience
Fanny Nadia Dissak-Delon, Guy-Roger Kamga, Perrine Claire Humblet, Annie Robert, Jacob Souopgui, Joseph Kamgno, Stephen Mbigha Ghogomu, Isabelle Godin   +7 more
doaj   +1 more source

Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis

Journal of Medicinal Chemistry, 2019
A series of pleuromutilins modified by introduction of a boron-containing heterocycle on C(14) of the polycyclic core are described. These analogs were found to be potent anti-Wolbachia antibiotics and, as such, may be useful in the treatment of filarial
R. Jacobs, C. Lunde, Y. Freund, Vincent Hernández, Xianfeng Li, Yi Xia, D. S. Carter, P. Berry, J. Halladay, F. Rock, Rianna Stefanakis, E. Easom, J. Plattner, L. Ford, K. Johnston, Darren Cook, R. Clare, A. Cassidy, Laura J. Myhill, Hayley E. Tyrer, Joanne Gamble, Ana F Guimaraes, A. Steven, F. Lenz, Alexandra Ehrens, Stefan J. Frohberger, Marianne Koschel, A. Hoerauf, M. Hübner, C. McNamara, M. Bakowski, J. Turner, M. Taylor, S. Ward   +33 more
semanticscholar   +1 more source

Treatment and prevention of epilepsy in onchocerciasis-endemic areas is urgently needed

Infectious Diseases of Poverty
Background There is increasing epidemiological evidence supporting the association between onchocerciasis and seizures, reinforcing the concept of onchocerciasis-associated epilepsy (OAE).
Robert Colebunders, Joseph Nelson Siewe Fodjo, Olivia Kamoen, Luís-Jorge Amaral, Amber Hadermann, Chiara Trevisan, Mark J. Taylor, Julia Gauglitz, Achim Hoerauf, Yasuaki Sato, Katja Polman, María-Gloria Basáñez, Dan Bhwana, Thomson Lakwo, Gasim Abd-Elfarag, Sébastien D. Pion   +15 more
doaj   +1 more source

Adherence to ivermectin is more associated with perceptions of community directed treatment with ivermectin organization than with onchocerciasis beliefs.

PLoS Neglected Tropical Diseases, 2017
BackgroundThe fight against onchocerciasis in Africa has boomed thanks to the Community Directed Treatment with Ivermectin (CDTI) program. However, in Cameroon, after more than 15 years of mass treatment, onchocerciasis prevalence is still above the non ...
Fanny Nadia Dissak-Delon, Guy-Roger Kamga, Perrine Claire Humblet, Annie Robert, Jacob Souopgui, Joseph Kamgno, Marie José Essi, Stephen Mbigha Ghogomu, Isabelle Godin   +8 more
doaj   +1 more source

Situation analysis of onchocerciasis in Cameroon: a protocol for systematic review of epidemiological studies and impact of disease control interventions

Systematic Reviews, 2020
Background Many control methods have been implemented to tackle onchocerciasis and great successes have been achieved, leading to a paradigm shift from control of morbidity to interruption of transmission and ultimately elimination.
Hugues C. Nana-Djeunga, André Domche, Yannick Niamsi-Emalio, Henri C. Moungui, Martin Walker, Maria-Gloria Basáñez, Joseph Kamgno   +6 more
doaj   +1 more source

Developing Strategies for Onchocerciasis Elimination Mapping and Surveillance Through The Diagnostic Network Optimization Approach

, 2021
Heidi Albert, Benn Sartorius, Paul R. Bessell, Dziedzom K. de Souza, Sidharth Rupani, Karla González, Simon Kayembe, Joseph Mathu Ndung’u, Rachel L. Pullan, Don Paul Makana, Maria Cecilia César de Almeida, Naomi Uvon   +11 more
openalex   +1 more source

Biting rates and relative abundance of Simulium flies under different climatic conditions in an onchocerciasis endemic community in Ghana [PDF]

, 2020
Kenneth Bentum Otabil, Samuel Fosu Gyasi, Esi Awuah, D. Obeng‐Ofori, Seth Boateng Tenkorang, Justice Amenyo Kessie, Henk D. F. H. Schallig   +6 more
openalex   +1 more source

Epidemiology of onchocerciasis-associated epilepsy in the Mbam and Sanaga river valleys of Cameroon: impact of more than 13 years of ivermectin

Infectious Diseases of Poverty, 2018
BackgroundA high epilepsy prevalence has been reported in several onchocerciasis-endemic villages along the Mbam and Sanaga river valleys in Cameroon, including Bilomo and Kelleng.
J. S. Siewe Fodjo, G. Tatah, E. Tabah, L. Ngarka, L. Nfor, S. Chokote, M. Mengnjo, F. Déma, Aurélien Guy Tele Sitouok, G. Nkoro, F. Ntone, A. Bissek, C. Chesnais, M. Boussinesq, R. Colebunders, Alfred K. Njamnshi   +15 more
semanticscholar   +1 more source

Prevalence of onchocerciasis and associated clinical manifestations in selected hypoendemic communities in Ghana following long-term administration of ivermectin

BMC Infectious Diseases, 2019
BackgroundOnchocerciasis is a neglected tropical disease which is still of immense major public health concern in several areas of Africa and the Americas. The disease manifests either as ocular or as dermal onchocerciasis with several symptoms including
K. Otabil, S. Gyasi, E. Awuah, D. Obeng-Ofori, Robert Junior Atta-Nyarko, Dominic Andoh, Beatrice Conduah, Lawrence Agbenyikey, P. Aseidu, C. Ankrah, A. Nuhu, H. Schallig   +11 more
semanticscholar   +1 more source

Would ivermectin for malaria control be beneficial in onchocerciasis-endemic regions?

Infectious Diseases of Poverty, 2019
Background There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated a reduced incidence of malaria in ...
Joseph Nelson Siewe Fodjo, Marina Kugler, An Hotterbeekx, Adam Hendy, Jean-Pierre Van Geertruyden, Robert Colebunders   +5 more
doaj   +1 more source