Results 111 to 120 of about 28,700 (244)
Modelling the elimination of river blindness using long-term epidemiological and programmatic data from Mali and Senegal [PDF]
, 2017 The onchocerciasis transmission models EPIONCHO and ONCHOSIM have been independently developed and used to explore the feasibility of eliminating onchocerciasis from Africa with mass (annual or biannual) distribution of ivermectin within the timeframes ...Basáñez, M-G, Bottomley, C, De Vlas, S J, Diawara, L, Dixon, M A, Stolk, W A, Traoré, M O, Walker, M +7 morecore +7 more sourcesNeglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms
Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.Moses Agbomhere Hamed, Olabanji Ahmed Surakat, Victor Olukayode Ekundina, Kabirat Bolajoko Jimoh, Adetomiwa Ezekiel Adeogun, Nafisat Omolola Akanji, Oluwafemi Joshua Babalola, Patrick Chukwunonso Eya, Rajib Chowdhury +8 morewiley +1 more sourceAn empirical method to estimate the effect of soil on the rate for transmission of damping‐off disease
, 2004 The ability of some soils to suppress soil-borne diseases has been long recognised, but the underlying epidemiological mechanisms by which this occurs are largely unknown.• Using damping-off disease caused by Rhizoctonia solani, spreading through ...Alabouvette C, Bailey DJ, C. A. Gilligan, Cook RJ, Dwyer G, Garrett KA, Gilligan CA, Gilligan CA, Gilligan CA, Hoper H, J. A. N. Filipe, Jeger MJ, Kleczkowski A, Nisbet RM, Otten W, Pielaat A, van den Bosch F, Van der Plank JE, W. Otten, Whipps JM +19 morecore +1 more sourceIn‐host modeling of dengue virus and non‐structural protein 1 and the effects of ivermectin in patients with acute dengue fever
CPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 12, Page 2196-2209, December 2024.Abstract
The increased incidence of dengue poses a substantially global public health challenge. There are no approved antiviral drugs to treat dengue infections. Ivermectin, an old anti‐parasitic drug, had no effect on dengue viremia, but reduced the dengue non‐structural protein 1 (NS1) in a clinical trial.Junjie Ding, Dumrong Mairiang, Dararat Prayongkul, Chunya Puttikhunt, Sansanee Noisakran, Nattapong Kaewjiw, Adisak Songjaeng, Tanapan Prommool, Nattaya Tangthawornchaikul, Nasikarn Angkasekwinai, Yupin Suputtamongkol, Keswadee Lapphra, Kulkanya Chokephaibulkit, Nicholas J. White, Panisadee Avirutnan, Joel Tarning +15 morewiley +1 more sourceBoron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis
Journal of Medicinal Chemistry, 2019 A series of pleuromutilins modified by introduction of a boron-containing heterocycle on C(14) of the polycyclic core are described. These analogs were found to be potent anti-Wolbachia antibiotics and, as such, may be useful in the treatment of filarial R. Jacobs, C. Lunde, Y. Freund, Vincent Hernández, Xianfeng Li, Yi Xia, D. S. Carter, P. Berry, J. Halladay, F. Rock, Rianna Stefanakis, E. Easom, J. Plattner, L. Ford, K. Johnston, Darren Cook, R. Clare, A. Cassidy, Laura J. Myhill, Hayley E. Tyrer, Joanne Gamble, Ana F Guimaraes, A. Steven, F. Lenz, Alexandra Ehrens, Stefan J. Frohberger, Marianne Koschel, A. Hoerauf, M. Hübner, C. McNamara, M. Bakowski, J. Turner, M. Taylor, S. Ward +33 moresemanticscholar +1 more sourceSocial sciences research in neglected tropical diseases 2: A bibliographic analysis [PDF]
, 2011 The official published version of the article can be found at the link below.Background
There are strong arguments for social science and interdisciplinary research in the neglected tropical diseases.A Anyamba, A Bauer, A Chang, A Dodoo, A Escalante, A Flahault, AJ Nederhof, AM Dondorp, B Huang, B Kwa, B Menne, B Tunç, C Chastel, C Di Lorenzo Oliveira, C Gloeckner, C Pérez-Guerra, C Ripert, C Vlassoff, D Amarakoon, D Campbell-Lendrum, D Claborn, D Freedman, D Gopalakrishnan, D Gubler, D Marom, Daniel D Reidpath, DD Reidpath, DL Heymann, E de Paula, E Vivas, F Bosello, F Coutinho, F Konradsen, F Mendez, G Rezza, G Shirish Kumar, H Delatte, H Ferguson, I Harper, J Kumar, J Lennon, J Lennon, J Lennon, J Nsungwa-Sabiiti, J Pearce-Duvet, J Pylypa, J Pylypa, J Raude, JDH Porter, JJ Esposito, K Kolivras, K Massa, K Nakhapakorn, K Phua, KE Mott, KJ Rothman, KR Popper, L Manderson, L Sánchez, M de Oliveira, M Garber, M Johansson, M Katabarwa, M Parker, M Parker, M Rosa-Freitas, M Setbon, M Sever-Prebilić, M Sriprom, M Sá, M Warsame, MJ Mackinnon, MM Cheng, N Katabarwa, ND Wolfe, O Abanobi, O Akogun, O Akogun, O Akogun, O Onwujekwe, O Onwujekwe, O Zerpa, P Allotey, P Allotey, P Arcari, P Fajardo, P Heller, P Mason, P Pongsumpun, P Weinstein, Pascale Allotey, PJ Hotez, PW Ewald, R Barrera, R Bate, R Castilla, R Development Core Team, R Othman, R Poulin, R Prothero, S Jeronimo, S Murthy, S Pokhrel, S Sengaloundeth, S Sáez, S Vanwambeke, SM Rich, Subhash Pokhrel, TS Kuhn, U Amazigo, U Amazigo, X Palacios, Y Samman +112 morecore +3 more sourcesCrystal structure of N‐terminally hexahistidine‐tagged Onchocerca volvulus macrophage migration inhibitory factor‐1
Acta Crystallographica Section F, Volume 80, Issue 12, Page 328-334, December 2024.N‐terminally hexahistidine‐tagged O. volvulus macrophage migration inhibitory factor‐1 has a unique jellyfish‐like structure with the prototypical macrophage migration inhibitory factor trimer as the `head' and a C‐terminal extension as the `tail'.Onchocerca volvulus causes blindness, onchocerciasis, skin infections and devastating neurological ...Amber D. Kimble, Omolara C. O. Dawson, Lijun Liu, Sandhya Subramanian, Anne Cooper, Kevin Battaile, Justin Craig, Elizabeth Harmon, Peter Myler, Scott Lovell, Oluwatoyin A. Asojo +10 morewiley +1 more sourceStage-specific proteomes from onchocerca ochengi, sister species of the human river blindness parasite, uncover adaptations to a nodular lifestyle [PDF]
, 2016 Despite 40 years of control efforts, onchocerciasis (river blindness) remains one of the most important neglected tropical diseases, with 17 million people affected.Adam, Altschul, Altschul, Anon, Argueta, Armstrong, Armstrong, Arumugam, Babayan, Bazzocchi, Bendtsen, Benjamini, Bennuru, Bennuru, Berry, Berry, Board, Boatin, Brattig, Brattig, Brophy, Bulman, Burbelo, Burchard, Burket, Butler, Chandrashekar, Chawade, Chhabra, Choi, Claros, Constam, Cooray, Crump, Darby, Darby, Desjardins, Duckert, Edgar, Edwards, Erttmann, Finn, Franceschini, Frank, Gallin, Gardon, GBD 2013 Mortality and Causes of Death Collaborators, Geary, Ghali, Ghedin, Ghosh, Gilbert, Globisch, Godel, Gomez-Escobar, Gopal, Gotenstein, Gottsch, Grainger, Gretes, Guan, Guiliano, Hansen, Henrichfreise, Hewitson, Hewitson, Hewitson, Hotez, Hunter, Ichishita, Joseph, Joza, Kanazawa, Klion, Ko, Koonin, Korten, Krogh, Larkin, Li, Li, Liebau, Liebau, Liebau, Liebau, Littler, Liu, Longo, Lu, Lundquist, Lustigman, Lustigman, Mackenzie, Makepeace, Marti, McGarry, McSorley, Melnikow, Meyer, Michalski, Morales-Hojas, Moreno, Moreno, Morris, Mossmann, Nana-Djeunga, Nfon, Nicholson, Nomura, Ohtsuki, Ohtsuki, Osei-Atweneboana, Page, Pant, Parra, Petersen, Plaisier, Quintana, Ranjan, Rew, Rogalski, Roth, Saitou, Schulz-Key, Schulz-Key, Scocchi, Sheehan, Silva, Sommer, Srivastava, Tamarozzi, Tanikawa, Taylor, Tchakouté, Ternent, Tew, Thompson, Tiwari, Trees, Vogel, Wahl, Waterhouse, Westermann, Wildenburg, Willenbucher, Wilson, Wisniewski, Wu, Wu, Xie, Xie, Yamaguchi, Yang, Yasuda, Zanetti, Zipfel +155 morecore +6 more sources
