Results 81 to 90 of about 28,700 (244)

The Role of Mathematical Modelling in Predicting and Controlling Infectious Disease Outbreaks in Underserved Settings: A Systematic Review and Meta‐Analysis

Public Health Challenges, Volume 4, Issue 3, September 2025.
ABSTRACT Background and Aim Mathematical modelling plays an important role in public health by enabling the prediction of disease outbreaks, assessment of transmission dynamics and evaluation of intervention strategies. Although widely applied in high‐resource settings, its use in underserved contexts remains underexplored. This review aimed to examine
Mavhunga Khumbudzo, Evans Duah, Estelle Grobler, Kuhlula Maluleke   +3 more
wiley   +1 more source

Dipteran succession on decomposing domestic pig carcasses in a rural area of southeastern Brazil

Scientific Reports
Diptera plays a pivotal role in forensic investigations, particularly in estimating the post-mortem interval. This can be achieved by analyzing the succession patterns of species on decomposing bodies, which requires detailed knowledge of the local fauna.
Carlos Henrique Garção-Neto, Lucas Barbosa Cortinhas, Paloma Martins Mendonça, Marina Lopes Duarte, Renato Tavares Martins, Margareth Maria de Carvalho Queiroz   +5 more
doaj   +1 more source

The macrofilaricidal efficacy of repeated doses of ivermectin for the treatment of river blindness [PDF]

, 2017
Background: Mass drug administration (MDA) with ivermectin is the cornerstone of efforts to eliminate human onchocerciasis by 2020 or 2025. The feasibility of elimination crucially depends on the effects of multiple ivermectin doses on Onchocerca ...
Basáñez, Maria-Gloria, Boussinesq, Michel, Chesnais, Cédric, Chippaux, Jean-Philippe, Ernould, Jean-Christophe, Fang, Hanwei, Garcia, André, Gardon, J., Kamgno, Joseph, Pion, Sébastien, Ranque, Stephane, Tchatchueng-Mbougua, Jules Brice, Walker, Martin   +12 more
core   +2 more sources

Epilepsy in onchocerciasis endemic areas: systematic review and meta-analysis of population-based surveys.

PLoS Neglected Tropical Diseases, 2009
ObjectiveWe sought to evaluate the relationship between onchocerciasis prevalence and that of epilepsy using available data collected at community level.DesignWe conducted a systematic review and meta-regression of available data.Data sourcesElectronic ...
Sébastien D S Pion, Christoph Kaiser, Fernand Boutros-Toni, Amandine Cournil, Melanie M Taylor, Stefanie E O Meredith, Ansgar Stufe, Ione Bertocchi, Walter Kipp, Pierre-Marie Preux, Michel Boussinesq   +10 more
doaj   +1 more source

Onchocerciasis dynamics: modelling the effects of treatment, education and vector control

Journal of Biological Dynamics, 2020
A deterministic model of onchocerciasis disease dynamics is considered in a community partitioned into compartments based on the disease status. Public health education is offered in the community during the implementation of mass treatment using ...
Asha Hassan, N. Shaban
semanticscholar   +1 more source

Low prevalence of epilepsy and onchocerciasis after more than 20 years of ivermectin treatment in the Imo River Basin in Nigeria

Infectious Diseases of Poverty, 2019
Background High epilepsy prevalence and incidence have been reported in areas with high onchocerciasis transmission. Recent findings suggest that proper community-directed treatment with ivermectin (CDTI) is potentially able to prevent onchocerciasis ...
Joseph N. F. Siewe, Chinyere N. Ukaga, Ernest O. Nwazor, Murphy O. Nwoke, Modebelu C. Nwokeji, Blessing C. Onuoha, Simon O. Nwanjor, Joel Okeke, Kate Osahor, Lilian Chimechefulam, Ann I. Ogomaka, Augustine A. Amaechi, Chika I. Ezenwa, Monika N. Ezike, Chidimma Ikpeama, Ogechi Nwachukwu, Austine I. Eriama-Joseph, Berthram E. B. Nwoke, Robert Colebunders   +18 more
doaj   +1 more source

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

Science Translational Medicine, 2019
An oral macrolide drug targeting the bacterial endosymbiont, Wolbachia, shows efficacy against filarial nematodes in preclinical animal models. Nematodes go A·WOL New drugs are urgently needed for treating the neglected tropical diseases, onchocerciasis ...
M. Taylor, T. V. von Geldern, L. Ford, M. Hübner, K. Marsh, K. Johnston, H. Sjoberg, S. Specht, N. Pionnier, Hayley E. Tyrer, R. Clare, Darren Cook, Emma Murphy, A. Steven, J. Archer, Dominique Bloemker, F. Lenz, Marianne Koschel, Alexandra Ehrens, Haelly M. Metuge, Valerinne C Chunda, Patrick W Ndongmo Chounna, A. Njouendou, Fanny F. Fombad, R. Carr, H. Morton, G. Aljayyoussi, A. Hoerauf, S. Wanji, D. Kempf, J. Turner, S. Ward   +31 more
semanticscholar   +1 more source

A mixed methods approach to evaluating community drug distributor performance in the control of neglected tropical diseases [PDF]

, 2016
BACKGROUND: Trusted literate, or semi-literate, community drug distributors (CDDs) are the primary implementers in integrated preventive chemotherapy (IPC) programmes for Neglected Tropical Disease (NTD) control.
A Wallace, AW Solomon, C Hanson, D Evans, EC Emukah, Fiona M. Fleming, FM Fleming, Fred Matovu, J Green, J Leslie, JA Wright, JC Okeibunor, JC Okeibunor, JH Kolaczinski, JH Kolaczinski, Joanne P. Webster, JS Dill, K Banek, KA Grepin, KL Leonard, Kristian S. Hansen, L Nkonki, M Callaghan, MA Bruijnzeels, MC Baker, MF Drummond, Ministry of Health, MN Katabarwa, MO Omedo, N Najnin, P Agyei-Baffour, P Akweongo, P Basinga, SC Francis, TK Ryman, UV Amazigo, V Wiseman, World Health Organisation, World Health Organisation, World Health Organization   +39 more
core   +3 more sources

Vitiligo

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 8, Page 968-987, August 2025.
Summary Vitiligo is a common pigment disorder of the skin resulting in destruction of melanocytes. Non‐segmental vitiligo (NSV) is an autoimmune disorder. The etiopathogenesis of segmental vitiligo (SV) remains incompletely understood. Genetic predisposition and increased vulnerability of melanocytes towards stressors lead to a melanocyte‐specific CD8+
Markus Böhm, Adrian Tanew
wiley   +1 more source

Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa

Infectious Diseases of Poverty, 2019
BackgroundOnchocerciasis (river blindness), caused by the filarial worm species Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public health and socioeconomic concern.
G. Gebrezgabiher, Z. Mekonnen, Delenasaw Yewhalaw, A. Hailu   +3 more
semanticscholar   +1 more source