Results 81 to 90 of about 28,317 (294)

Investigation of publication trends and hot topics on onchocerciasis between 2000 and 2022

Journal of Zoonotic Diseases, 2023
This study aimed to use bibliometric tools to investigate onchocerciasis research conducted worldwide between 2000 and 2022. This bibliometric study was carried out using the Scopus database.
Sevil Alkan, Esra Gürbüz, Selahattin Aydemir   +2 more
doaj   +1 more source

Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis

Science Translational Medicine, 2019
An oral macrolide drug targeting the bacterial endosymbiont, Wolbachia, shows efficacy against filarial nematodes in preclinical animal models. Nematodes go A·WOL New drugs are urgently needed for treating the neglected tropical diseases, onchocerciasis ...
M. Taylor, T. V. von Geldern, L. Ford, M. Hübner, K. Marsh, K. Johnston, H. Sjoberg, S. Specht, N. Pionnier, Hayley E. Tyrer, R. Clare, Darren Cook, Emma Murphy, A. Steven, J. Archer, Dominique Bloemker, F. Lenz, Marianne Koschel, Alexandra Ehrens, Haelly M. Metuge, Valerinne C Chunda, Patrick W Ndongmo Chounna, A. Njouendou, Fanny F. Fombad, R. Carr, H. Morton, G. Aljayyoussi, A. Hoerauf, S. Wanji, D. Kempf, J. Turner, S. Ward   +31 more
semanticscholar   +1 more source

Reaching the last mile: main challenges relating to and recommendations to accelerate onchocerciasis elimination in Africa

Infectious Diseases of Poverty, 2019
BackgroundOnchocerciasis (river blindness), caused by the filarial worm species Onchocerca volvulus, is a serious vector-borne neglected tropical disease (NTD) of public health and socioeconomic concern.
G. Gebrezgabiher, Z. Mekonnen, Delenasaw Yewhalaw, A. Hailu   +3 more
semanticscholar   +1 more source

FDA‐approved drugs featuring macrocycles or medium‐sized rings

Archiv der Pharmazie, Volume 358, Issue 1, January 2025.
This review presents 17 macrocyclic drugs approved by the U.S. Food and Drug Administration during the past 5 years, highlighting their importance and critical role in modern therapeutics, and the innovative synthetic approaches for the construction of these macrocycles.
Youlong Du, Anas Semghouli, Qian Wang, Haibo Mei, Loránd Kiss, Daniel Baecker, Vadim A. Soloshonok, Jianlin Han   +7 more
wiley   +1 more source

An 18S ribosomal DNA barcode for the study of Isomermis lairdi, a parasite of the blackfly Simulium damnosum s.l.

, 2009
The mermithid parasite, Isomermis lairdi Mondet, Poinar & Bernadou (Nematoda: Mermithidae), is known to have a major impact on populations of Simulium damnosum s.l. Theobald (Diptera: Simuliidae) and on their efficiency as vectors of Onchocerca volvulus (
Blaxter, Borsboom, Colbo, Crosskey, Crosskey, Davies, Finney, Floyd, Foottit, Holterman, Kaiser, Molloy, Molloy, Mondet, Mondet, Mondet, Osei-Atweneboana, Platzer, Poinar, Poinar, Post, Rubstov, St-Onge, Van Emden, Vandergast, Walsh, Wilson   +26 more
core   +1 more source

Epilepsy in onchocerciasis endemic areas: systematic review and meta-analysis of population-based surveys.

PLoS Neglected Tropical Diseases, 2009
ObjectiveWe sought to evaluate the relationship between onchocerciasis prevalence and that of epilepsy using available data collected at community level.DesignWe conducted a systematic review and meta-regression of available data.Data sourcesElectronic ...
Sébastien D S Pion, Christoph Kaiser, Fernand Boutros-Toni, Amandine Cournil, Melanie M Taylor, Stefanie E O Meredith, Ansgar Stufe, Ione Bertocchi, Walter Kipp, Pierre-Marie Preux, Michel Boussinesq   +10 more
doaj   +1 more source

Onchocerciasis-associated epilepsy in the Democratic Republic of Congo: Clinical description and relationship with microfilarial density

PLoS Neglected Tropical Diseases, 2019
Background High epilepsy prevalence and incidence were observed in onchocerciasis-endemic villages in the Democratic Republic of Congo (DRC). We investigated the clinical characteristics of onchocerciasis-associated epilepsy (OAE), and the relationship ...
J. S. Siewe Fodjo, M. Mandro, D. Mukendi, F. Tepage, S. Menon, Swabra Nakato, F. Nyisi, Germain M Abhafule, Deogratias Wonya'rossi, Aimé Anyolito, Richard Lokonda, A. Hotterbeekx, R. Colebunders   +12 more
semanticscholar   +1 more source

Development of RP‐HPLC Method for Simultaneous Determination of Triclabendazole and Ivermectin in Pharmaceutical Suspension Dosage Form

Journal of Analytical Methods in Chemistry, Volume 2025, Issue 1, 2025.
A reversed‐phase high‐performance liquid chromatography (RP‐HPLC) method was developed for simultaneous determination of triclabendazole (TCB) and ivermectin (IVM) in pharmaceutical dosage form. A mobile phase consisting of acetonitrile/water (50:50 v/v) with a flow rate of 1.5 mL/min was used for chromatographic separation of the mixture of TCB and ...
Taj Ur Rahman, Ajmal Zaman, Ali Bahadur, Muhammad Aurang Zeb, Wajiha Liaqat, Eman Y. Santali, Sarah Alharthi, Ruwida M. K. Omar, Saif A. Alharthy, Ashraf Ali, Alessandro Buccolieri   +10 more
wiley   +1 more source

Ivermectin - old drug, new tricks? [PDF]

, 2017
Ivermectin is one of the most important drugs in veterinary and human medicine for the control of parasitic infection and was the joint focus of the 2015 Nobel Prize in Physiology or Medicine, some 35 years after its remarkable discovery.
Devaney, Eileen, Gillan, Victoria, Laing, Roz   +2 more
core   +1 more source

Spatial clustering of onchocerciasis in Bioko Island, Equatorial Guinea

Journal of Infection in Developing Countries, 2018
Introduction: Onchocerciasis is a chronic neglected tropical disease caused by the filarial nematode Onchocerca volvulus, which is endemic in Equatorial Guinea.
Diana Gómez-Barroso, Laura Moya, Zaida Herrador, Belén García, Justino Nguema, Policarpo Ncogo, Pilar Aparicio, Agustín Benito   +7 more
doaj   +1 more source