Results 171 to 180 of about 846,916 (323)

The vitamin D-responsive element in the human osteocalcin gene. Association with a nuclear proto-oncogene enhancer.

, 1990
Keiichi Ozono, Jennifer Liao, Sandra A. Kerner, R. Scott, J. Wesley Pike   +4 more
openalex   +1 more source

Exploration of Novel Biomarkers Through a Precision Medicine Approach Using Multi‐Omics and Brain Organoids in Patients With Atypical Depression and Psychotic Symptoms

Advanced Science, EarlyView.
This study examines major depressive disorder with atypical features and psychotic symptoms through a multi‐omics precision medicine approach. By integrating clinical assessments, WBC scRNA‐seq, plasma proteomics, and brain organoid models, it uncovers immune dysregulation, synaptic protein alterations, and stress‐sensitive neuronal changes.
Insook Ahn, Soyeon Chang, Jiyoung Lee, Seok‐Ho Choi, Jinju Han, Yangsik Kim   +5 more
wiley   +1 more source

A prospective, multicenter, comprehensive genomic profile signature study in patients with EGFR-mutant advanced non-small cell lung cancer at the first-line treatment failure of osimertinib. [PDF]

Signal Transduct Target Ther
Shi Y, Lv D, Feng W, Liu S, Xing P, Yu Y, Yin J, Ren X, Zhang J, Han G, Zhang Y, Cang S, Chen J, Chen E, Meng L, Zhang Y.   +15 more
europepmc   +1 more source

STAT1‑HDAC4 signaling induces epithelial‑mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2

, 2018
Sirichat Kaowinn, Chutima Kaewpiboon, Sang Seok Koh, Oliver Kr�mer, Young‐Hwa Chung   +4 more
openalex   +2 more sources

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Author Correction: Characterisation of a cyclic peptide that binds to the RAS binding domain of phosphoinositide 3-kinase p110α

Scientific Reports
Mohamed Ismail, Stephen R. Martin, Roger George, Francesca Houghton, Geoff Kelly, Raphaël A. G. Chaleil, Panayiotis Anastasiou, Xinyue Wang, Nicola O’Reilly, Stefania Federico, Dhira Joshi, Hemavathi Nagaraj, Rachel Cooley, Ning Sze Hui, Miriam Molina‑Arcas, David C. Hancock, Ali Tavassoli, Julian Downward   +17 more
doaj   +1 more source

Correction: Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity. [PDF]

Oncogene
Cherif C, Nguyen DT, Paris C, Le TK, Sefiane T, Carbuccia N, Finetti P, Chaffanet M, El Kaoutari A, Vernerey J, Fazli L, Gleave M, Manai M, Barthélémy P, Birnbaum D, Bertucci F, Taïeb D, Rocchi P.   +17 more
europepmc   +1 more source

ONCOGENES AND ANTI-ONCOGENES [PDF]

Pediatric Research, 1986
openaire   +1 more source

CircLRBA Promotes Epithelial‐Mesenchymal Transition, Immune Evasion, Chemoimmunotherapy Resistance and Metastasis Through Stabilizing Twist1

Advanced Science, EarlyView.
CircLRBA is highly expressed in breast cancer (BC) and associated with poor overall survival. Zeb1 mediated circLRBA facilitates BC cell proliferation, invasion, docetaxel (DTX) resistance and inhibits the infiltration of CD8+ T cell. CircLRBA could combine with SPOP to suppress the Twist1 ubiquitination degradation and enhances PD‐L1 transcription ...
Xiaosong Wang, Xin Yang, Lei Xing, Hang Chen, Fuming Xie, Bin Wang, Bowen Shi, Yan Yang, Junxia Chen   +8 more
wiley   +1 more source

3D-bioprinted liver cancer models derived from primary hepatocytes for simulating cancer initiation and drug screening. [PDF]

Hepatol Commun
Zhao Y, Li Y, Zhang W, Jiang H, Mao L, He R, Ma Y, Wang Q, Huang P.   +8 more
europepmc   +1 more source