Results 181 to 190 of about 846,916 (323)

Integrative Omics Reveal Female‐Specific Benefits of p16+ Cell Clearance in Aging Mice

open access: yesAdvanced Science, EarlyView.
Aging causes accumulation of p16⁺ senescent cells that promote inflammation and dysfunction. Multi‐omics analyses reveal striking sex differences in senescent cell burden and clearance: females accumulate more p16⁺ cells, especially in the liver, and their removal rejuvenates molecular and functional profiles.
Yao Lin   +4 more
wiley   +1 more source

Sirtuin 1 and Sirtuin 2 Gene Expressions in Colorectal Cancers. [PDF]

open access: yesJ Clin Pract Res
Düzenli T, Doğan D, Barışık NÖ.
europepmc   +1 more source

Up-regulation of c-Cbl suggests its potential role as oncogene in primary colorectal cancer [PDF]

open access: bronze, 2014
Ion Cristóbal   +6 more
openalex   +1 more source

Supplemental Table 2 from Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis

open access: gold, 2023
Laura Quick   +6 more
openalex   +1 more source

Clinofibrate Disrupts the SNORA80B/YTHDC1‐Driven M6A Modification to Suppress Cholesterol Metabolism and Cisplatin Resistance in ESCC

open access: yesAdvanced Science, EarlyView.
This study uncovers a non‐canonical role of SNORA80B in ESCC, showing it mediates AR‐driven metabolic reprogramming via N⁶‐methyladenosine (m6A) methylation. By binding YTHDC1, SNORA80B stabilizes cholesterol‐metabolic enzyme mRNAs and promotes tumor progression. The FDA‐approved drug clinofibrate inhibits SNORA80B by disrupting cholesterol homeostasis,
Hongyu Yuan   +7 more
wiley   +1 more source

Correction: M6A-mediated-upregulation of lncRNA BLACAT3 promotes bladder cancer angiogenesis and hematogenous metastasis through YBX3 nuclear shuttling and enhancing NCF2 transcription. [PDF]

open access: yesOncogene
Xie J   +14 more
europepmc   +1 more source

Proliferation of human myeloid leukemia cell line associated with the tyrosine-phosphorylation and activation of the proto-oncogene c-kit product [PDF]

open access: bronze, 1991
A Kuriu   +9 more
openalex   +1 more source

Table S5 from The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

open access: gold, 2023
Juliane L. Buhl   +30 more
openalex   +1 more source

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