Results 181 to 190 of about 577,954 (290)

A737 DIFFERENTIAL C-FOS ONCOGENE EXPRESSION IN MECHANICALLY- VERSUS CHEMICALLY-INDUCED VISCERAL NOCICEPTION [PDF]

, 1990
Joyce A. DeLeo, Dennis W. Coombs, Lawrence E. McCarthy   +2 more
openalex   +1 more source

Functional, Pharmacogenomic, and Immune Landscapes of Long Non‐Coding RNAs in Cancer

Advanced Science, EarlyView.
A systematic analysis of 33 cancer types reveals widespread associations between lncRNAs and cancer pathways, drug responses, immune features, and immunotherapy outcomes. The study identifies key lncRNAs linked to therapeutic response and adverse events and introduces PILNC, an interactive web portal for exploring the functional, pharmacogenomic, and ...
Runhao Wang, Mei Luo, Yuan Liu, Jingwen Yang, Yamei Chen, Chengxuan Chen, Lifei Ma, Stephanie Ding, James Wengler, Yong Zang, Bora Lim, Wenbo Li, Liuqing Yang, Chunru Lin, Lixia Diao, Leng Han   +15 more
wiley   +1 more source

Clinical characteristics and prognostic analysis of three hundred and nineteen cases of primary gastrointestinal diffuse large B-cell lymphoma. [PDF]

World J Gastrointest Oncol
Ma JJ, Zhang H, Wang CC, Ji WL, Zhao Y, Li XX.   +5 more
europepmc   +1 more source

Inclusion of the ASH1 gene that governs the neuroendocrine differentiation of lung epithelium as an additional prototypic 'lineage-survival oncogene' [PDF]

, 2006
Levi A. Garraway, William R. Sellers
openalex   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Exploring a mutation-based signature to predict the benefits of immune checkpoint inhibitors in oncogene-addicted subsets of non-small cell lung cancer: a retrospective study. [PDF]

Respir Res
Huang J, Lei J, Xiao B, Kang W, Sui Z, Deng Y, Jia R, Huang C, Cai S.   +8 more
europepmc   +1 more source

Comparison of expression values of ecDNA-related oncogenes between primary tumor and solid tissue normal in TCGA-ESCA.

Mingjun Li (178925), Lei Li (29537), Xizi Wang (838412), Yanwei Zhao (1725145), Peina Du (5672948), Wei Wang (17594), Zhenxing Wang (201180), Yadong Wang (82064), Yanxing Sheng (9539585), Mingliang Gu (159631), Xiaodong Jia (783460)   +10 more
openalex   +1 more source

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao, Jing Yu, Xin Wang, Xu Liu, Fengli Zuo, Tianyue Xu, Leyi Tang, Ling Xiong, Li Li, Huifang Li, Xiaoting Chen, Guang Yang, Jing Jing, Xiaowei Liu   +13 more
wiley   +1 more source

3D-bioprinted liver cancer models derived from primary hepatocytes for simulating cancer initiation and drug screening. [PDF]

Hepatol Commun
Zhao Y, Li Y, Zhang W, Jiang H, Mao L, He R, Ma Y, Wang Q, Huang P.   +8 more
europepmc   +1 more source

Oncogene addiction [PDF]

Current Biology, 2012
openaire   +2 more sources