Results 181 to 190 of about 172,205 (306)

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source

CUX1::MET fusion defines an indolent subtype of diffuse low-grade glioma, MAPK pathway-altered. [PDF]

Acta Neuropathol Commun
Nagashima H, Takeuchi Y, Jimbo N, Matsuda H, Kimbara S, Tanaka K, Sasayama T.   +6 more
europepmc   +1 more source

The oncogenic fusion protein CBFB-SMMHC downregulates CD48 to evade NK cell recognition [PDF]

Blood Cancer Journal, 2018
Kahlon, Shira, Shreibman, Dorin, Unger, Tamar, Ben-Yehuda, Dina, Elias, Shlomo   +4 more
openaire   +2 more sources

Comprehensive analysis and functional validation of key genes in bladder cancer progression

VIEW, EarlyView.
Bladder cancer is highly diverse between patients, making it difficult to accurately predict who will have aggressive disease and poor outcomes. In this study, we integrated single‐cell RNA sequencing with clinical survival data to identify a simple three‐gene signature (FAM3B, C10orf99, and VMP1) that stratifies patients into high‐ and low‐risk groups.
Xiaoning Cheng, Hongxia Zhao, Qian Li, Boyang Liu, Maoping Cai, Xinyi Wang, Jiancong Lie, Yuanyuan Qu, Jianwei Li, Chunlong Yang   +9 more
wiley   +1 more source

RET Signaling Pathway in Human Cancer: Oncogenic Mechanisms, Selective Inhibitors, and Emerging Resistance Strategies. [PDF]

Int J Mol Sci
Streit S, Dweik A, Mahtab A, Ali S, Khan A, Salzberg M.   +5 more
europepmc   +1 more source

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng, Ling‐Mei Qu, Jun‐Jie Liu, Yu‐Shan Li, Zi‐Qi Chen, Shuo Liu, Zhao‐Nan Xu, Meng Jin, Qiu‐Ying Li, Qin Wu, Hong‐Tian Yi, Xian‐Ji Shen, Bing‐Rui Yan, Ya‐Nan Sun   +13 more
wiley   +1 more source

Human Mesenchymal Stem Cell-Derived Exosomes as Engineering Vehicles of Daunorubicin for Targeted c-Mpl+ AML Therapy

International Journal of Nanomedicine
Chunmou Li,1,* Yuchen Wen,1,* Jiasheng Wang,2 Lindi Li,1 Yue He,2 Yucai Cheng,1 Junru Chen,2 Junbin Huang,1 Cheng Ouyang,1 Yong Liu,1 Ruizhi Zhou,1 Haisheng Chen,2 Fei Li,2 Qiqi Guo,2 Yun Chen,3 Chun Chen,1 Qing Zhang2 1Pediatric Hematology ...
Li C, Wen Y, Wang J, Li L, He Y, Cheng Y, Chen J, Huang J, Ouyang C, Liu Y, Zhou R, Chen H, Li F, Guo Q, Chen Y, Chen C, Zhang Q   +16 more
doaj  

Pleural-Based GLI1-Altered Mesenchymal Tumor With ACTB-GLI1 Fusion: A Rare Pulmonary Entity Mimicking Synovial Sarcoma. [PDF]

Thorac Cancer
Lizwan M, Xiao L, Chow CY, Lau HY, Ong BH.   +4 more
europepmc   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

TMPRSS2:ERG-directed radiosensitization: exploiting DNA repair rewiring in gene fusion-positive prostate cancer. [PDF]

J Clin Invest
Wang X, Chinnaiyan AM.
europepmc   +1 more source