Results 231 to 240 of about 369,580 (326)

Peptide‑based therapeutics targeting the SLC39A14‑PIWIL2 fusion in hepatocellular carcinoma. [PDF]

Genomics Inform
Shah M, Moon SU, Choi JH, Kim MJ, Woo HG.   +4 more
europepmc   +1 more source

Cellular Signalling Networks in High Altitude Pulmonary Hypertension: From Canonical Pathways to Emerging Targets

Cell Proliferation, EarlyView.
This review elucidates the intricate cellular signalling networks involved in high‐altitude pulmonary hypertension (HAPH), integrating canonical pathways like HIF, MAPK and BMP with emerging targets such as Wnt/β‐catenin, Notch, Hippo‐YAP and IL‐6. It highlights potential therapeutic strategies targeting these pathways to mitigate vascular remodelling ...
Sheng Ding, Ju Chen, Zhaoyang Li, Yang Yu, Weijie Wang, Yan Liao, Jin Yang, Dianxiang Lu, Yujiang Fan   +8 more
wiley   +1 more source

Disrupting resistance: novel therapeutic approaches to combat multidrug resistance in fusion-negative rhabdomyosarcoma. [PDF]

Cancer Drug Resist
Codenotti S, Marampon F, Megiorni F, Cattaneo CG, Gastaldello S, Pozzo E, Sampaolesi M, Rota R, Keller C, Fanzani A.   +9 more
europepmc   +1 more source

Cell fusion promotes chemoresistance in metastatic colon carcinoma

Oncogene, 2013
V. Carloni, A. Mazzocca, T. Mello, Andrea Galli, Sergio Capaccioli   +4 more
semanticscholar   +1 more source

HPV42 – a human papillomavirus classified as a low‐risk type with oncogenic potential

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Human papillomavirus (HPV) type 42 is a rare HPV type currently classified as “low‐risk” and belongs to the alpha genus. It has primarily been detected in benign vulvar papillomas and is predominantly associated with benign lesions such as anogenital warts.
Sven Niklas Burmann, Ulrike Wieland, Steffi Silling, Frank Oellig, David Chromy, Julia Hyun, Thilo Gambichler, Alexander Kreuter   +7 more
wiley   +1 more source

Pediatric NUT carcinoma: a patient series and literature review. [PDF]

BMC Pediatr
You Y, Lu S, Sun F, He X, Wang J, Huang J, Que Y, Zhen Z, Zhang Y, Zhu J.   +9 more
europepmc   +1 more source

LAT1/SLC7A5‐mediated amino acid uptake is regulated by redox signals triggered by formyl‐peptide receptor 2

The FEBS Journal, EarlyView.
FPR2 activation mediates NOX‐dependent LAT1 expression and, in turn, promotes mTORC1 signaling. Upon stimulation with WKYMVm, the FPR2‐NOX2‐ROS axis upregulates LAT1 via increased c‐Myc phosphorylation and decreased miR‐126. Additionally, it promotes CD98 translocation to the plasma membrane.
Myrhiam Cassese, Chiara Brignola, Stefano Marrone, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo   +5 more
wiley   +1 more source

Tropomyosin 3 Gene Fusions in Cancers: From Mechanisms to Treatments-A Comprehensive Review. [PDF]

Cancer Med
Chen A, Li S, Guo C, Gu C, Gui J, Deng Y, Feng X, Mi Y.   +7 more
europepmc   +1 more source

RARα-PLZF oncogene inhibits C/EBPα function in myeloid cells

Proceedings of the National Academy of Sciences of the United States of America, 2013
N. Girard, Mathieu Tremblay, Magali Humbert, B. Grondin, A. Haman, J. Labrecque, Bing Chen, Zhu Chen, Saijuan Chen, T. Hoang   +9 more
semanticscholar   +1 more source

PAX8‐positive conventional urothelial carcinomas of the urinary bladder and their distinct molecular profiles – A clinicopathologic study of 101 consecutive cases with next‐generation sequencing in 20 cases

Histopathology, EarlyView.
PAX8 expression in urothelial carcinoma was investigated in 101 consecutive transurethral resections of the urinary bladder. PAX8 was positive in 10% of cases, with targeted molecular testing of these cases revealing universal TERT promoter mutations and frequent alterations in TSC1, NOTCH1 and WT1. Aims PAX8 immunohistochemistry (IHC) is often used to
Sarah Mae Lammert, Wendy Luo, Allen C Zhu, Peng Wang, Tatjana Antic, Jung Woo Kwon   +5 more
wiley   +1 more source