Results 261 to 270 of about 103,602 (308)

Structure, mechanism and clinical relevance of NRG1 fusions in cancer. [PDF]

J Biomed Sci
Thiollier-Schmitt C, Barre M, Issenmann M, Cros-Perrial E, Duruisseaux M, Jordheim LP.   +5 more
europepmc   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

A Complete Response to Immunotherapy in a Patient with Locally Advanced Squamous Cell Lung Cancer Harboring a Novel <i>TMEM178B::BRAF</i> Fusion: A Case Report. [PDF]

Diagnostics (Basel)
Redondo-González JC, San Miguel I, Rodríguez-González M, Montero JC, Sayagués JM, Abad Hernández M, Fonseca Sánchez E, Del Barco-Morillo E, Olivares-Hernández A.   +8 more
europepmc   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

International Journal of Cancer, Volume 159, Issue 1, Page 144-158, 1 July 2026.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho, Fabio Nunes de Mello, Ana Carolina Tahira, Gabriel Nakanishi Fortes, Agatha Fischer‐Carvalho, Pedro Jardim Poli, Murilo Sena Amaral, Sergio Verjovski‐Almeida   +7 more
wiley   +1 more source

Identification of Actionable Gene Variants in Pulmonary Large-Cell Neuroendocrine Carcinoma: A Real-World Analysis of a Polish Cohort. [PDF]

Int J Mol Sci
Szpechcinski A, Pelc M, Lechowicz U, Szolkowska M, Moes-Sosnowska J, Rudzinski P, Wojda E, Skronska P, Podgorska E, Maszkowska-Kopij K, Polaczek M, Orlowski T, Langfort R, Chorostowska-Wynimko J.   +13 more
europepmc   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

Medicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca, Mariana Feijó, Cátia V. Vaz, Bruno J. Pereira, Sandra Laurentino, Ana Palmeira‐de‐Oliveira, Sílvia Socorro   +6 more
wiley   +1 more source

Isolated signals in BCL2, MYC, BCL6, and DDIT3 FISH: implications for genetic alterations and protein dysregulation. [PDF]

Pathol Oncol Res
Wei Z, Chen Q, Feng Z, Tang F.
europepmc   +1 more source

CRISPR‐Cas9 Genome‐Wide Screening in Paediatric Cancer: Functional Genomics for Target Discovery and the Improvement of Existing Therapies

Medicinal Research Reviews, Volume 46, Issue 4, Page 989-1004, July 2026.
ABSTRACT CRISPR‐Cas9 genome‐wide screening has been instrumental towards identifying novel targets for drug discovery in cancer research. However, much of this research has centred specifically on adult cancers, with paediatric cancers being underserviced by current research and screening.
Steven He, Patrick Connerty, Antoine de Weck   +2 more
wiley   +1 more source

In Silico Design and Characterization of a Rationally Engineered Cas12j2 Gene Editing System for the Treatment of HPV-Associated Cancers. [PDF]

Int J Mol Sci
Boren C, Kumar R, Gollahon L.
europepmc   +1 more source

The Cyclin C-CDK8/19 Mediator kinase module controls PRCC-TFE3 driven senescence in renal epithelium and tumorigenesis in TFE3-RCC. [PDF]

Neoplasia
Kuroda S, Funasaki S, Nishizawa H, Schmidt LS, Kurahashi R, Ito T, Arima Y, Tanaka M, Kitada A, James AM, Hasumi H, Jikuya R, Makiyama K, Kurotaki D, Minami T, Difilippantonio S, Linehan WM, Oike Y, Sawa T, Tanaka Y, Suda T, Yokokawa R, Nakamura T, Baba M, Kamba T.   +24 more
europepmc   +1 more source