Results 291 to 300 of about 369,580 (326)

Biological Templates for Gold Nanocluster Assembly: Design and Biomedical Applications

Aggregate, Volume 7, Issue 2, February 2026.
The review discusses the fundamental properties of ultrasmall gold nanoclusters and their surface modification strategies for targeted biomedical use. It examines biologically guided assembly processes and their effects on optical behavior, particularly aggregation‐induced emission.
Zeineb Ayed, Abdallah Alhalabi, Didier Gasparutto, Xavier Le Guével   +3 more
wiley   +1 more source

Novel Case of a Molecularly Confirmed Low-Grade Fibromyxoid Sarcoma of the Floor of the Mouth and Literature Review. [PDF]

Head Neck Pathol
Bestman EG, Brooks JK, Nelson SD, Sultan AS, Hawari N, Jeffrey SL, Uyanne J, Yip FK, Artis K, Nakasaki M.   +9 more
europepmc   +1 more source

An OGT Missense Variant With Impaired Enzyme Activity in a Child With Severe Developmental Delay and Hepatoblastoma

American Journal of Medical Genetics Part A, Volume 200, Issue 2, Page 502-510, February 2026.
ABSTRACT O‐GlcNAc transferase (OGT) and its antagonist O‐GlcNAcase (OGA) regulate protein O‐GlcNAcylation, a highly conserved post‐translational modification involved in metabolic sensing. Pathogenic variants in the OGT gene cause an X‐linked congenital disorder of glycosylation (OGT‐CDG) presenting developmental delay, hypotonia, intellectual ...
Alfonso Manuel D'Alessio, Huijie Yuan, Leandro Raul Soria, Sara Basse Hansen, Iolanda Boffa, Paola Arena, Benedetta Attianese, Maureen. O'Sullivan, Noelle Cullinan, Lewis Pang, Daan Marinus Ferdinand van Aalten, Nicola Brunetti‐Pierri, Sally Ann Lynch   +12 more
wiley   +1 more source

Novel BMP2K::PDGFRA fusion in an unusual myeloid/lymphoid neoplasm with eosinophilia. [PDF]

J Hematop
Bommu RT, Mnayor LO, Tashakori M, Yohe S.   +3 more
europepmc   +1 more source

Harmine Derivatives as Anticancer Agents Endowed With Potent and Selective Antileukemia Activity: Synthesis, Biological Evaluation, Proapoptotic and Genotoxic Activity

Archiv der Pharmazie, Volume 359, Issue 2, February 2026.
We identified a novel N9‐substituted harmine analog, compound 6, that selectively suppresses leukemic cell growth, triggers DNA damage, and activates apoptosis while sparing healthy fibroblasts. This discovery highlights N9‐modified β‐carbolines as a powerful new class of selective antileukemic agents, bridging natural product chemistry with next ...
Abdul Aziz Timbilla, Filip Pidany, Eliska Kohelova, Jana Kroustkova, Karel Kralovec, Jan Rataj, Martina Ceckova, Negar Maafi, Víctor Lopez, Cristina Moliner Langa, Stefan Kosturko, Jaroslav Jenco, Darina Muthna, Darja Koutova, Martina Rezacova, Lucie Cahlikova, Jakub Chlebek, Radim Havelek   +17 more
wiley   +1 more source

Subgroup of meningiomas involving FOS and FOSB gene fusions. [PDF]

Nat Commun
Yalcin K, Alanya H, Gultekin B, Samper Figuera D, Barak T, Miyagishima DF, Youngblood MW, Hjerthen MG, Brooks A, Samuel Lopez N, O'Brien J, Chavez MM, Dincer A, Wu H, Omay SB, Yasuno K, Bilguvar K, Ercan-Sencicek AG, Mishra-Gorur K, McGuone D, Moliterno J, Gunel M, Erson-Omay EZ.   +22 more
europepmc   +1 more source

Molecular and epigenetic oncogenesis in synovial sarcoma: implications for cancer biology, diagnosis and treatment. [PDF]

Oncogene
Wang AX, Jones KB, Nielsen TO.
europepmc   +1 more source

Synovial sarcoma reprograms transcription by GBAF activation of polycomb targets and loss of CBAF enhancers. [PDF]

Nat Commun
Li J, Li L, Smith-Fry K, Fadlullah MZ, Carroll L, Morrison L, Ge X, Nelson ML, Hill LA, Guo Y, Davenport G, Zhang X, Nielsen TO, Hirst M, Underhill TM, Cairns BR, Jones KB.   +16 more
europepmc   +1 more source

EWS::FLI1 expression in human embryonic mesenchymal stem cells leads to transcriptional reprograming, defective DNA damage repair and Ewing sarcoma. [PDF]

Nat Commun
Hernández-Muñoz I, Cuervas I, Prada E, Pulecio J, Gimeno R, Andrades E, Gómez-González S, Berenguer-Molins P, Acedo-Terrades A, Perera-Bel J, Bódalo-Torruella M, Nonell L, Pérez E, Grases D, Mata C, Yélamos J, Richaud-Patin Y, Vidal E, Cuartero Y, Le Dily F, Suñol M, Manzanares A, Raya A, Mora J.   +23 more
europepmc   +1 more source

Expanding the spectrum of <i>AFF2</i> undifferentiated sarcoma associated to endometriosis: a novel <i>ZDHHC9::AFF2</i> fusion sarcoma with high-grade features and poor prognosis. [PDF]

Pathologica
Arciuolo D, Alaggio R, Travaglino A, Scaglione G, Santoro A, Giovannoni I, Barresi S, Patrizi S, Miele E, Pedone Anchora L, Inzani F, Zannoni GF.   +11 more
europepmc   +1 more source