Results 271 to 280 of about 172,205 (306)

Accurate <i>RET</i> Fusion Detection in Solid Tumors Using RNA Sequencing Coverage Imbalance Analysis. [PDF]

Int J Mol Sci
Gaziev I, Khristichenko A, Luppov D, Suntsova M, Bondarenko E, Reinberg M, Matrosova A, Khilal N, Sorokin M, Sekacheva M, Poddubskaya E, Buzdin A, Zakharova G.   +12 more
europepmc   +1 more source

RNA-Sequencing Reveals Two Subgroups of Eccrine Porocarcinomas and Poromas. [PDF]

J Cell Mol Med
Puttonen M, Kilpinen S, von Willebrand M, Ojala K, Böhling T, Koljonen V, Sihto H.   +6 more
europepmc   +1 more source

Next-generation liquid biopsies: detecting circulating epigenetic changes to identify translocation renal cell carcinoma. [PDF]

J Clin Invest
Ito K, Braun DA.
europepmc   +1 more source

Overexpression of the ERG oncogene in prostate cancer identifies candidates for PARP inhibitor-based radiosensitization. [PDF]

J Clin Invest
Köcher S, Elsesy ME, Moustafa A, Mohammadi W, Perugachi Heinsohn A, Nagaraj Y, Oh-Hohenhorst SJ, Hahn J, Siebels B, Mair T, Burdak-Rothkamm S, Tennstedt P, Simon R, Lange T, Tilki D, Frenzel T, Maurer T, Petersen C, Schlüter H, Bokemeyer C, von Amsberg G, Rothkamm K, Mansour WY.   +22 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Development of a degrader against oncogenic fusion protein FGFR3-TACC3

Bioorganic & Medicinal Chemistry Letters, 2022
Fibroblast growth factor receptor 3-transforming acidic coiled-coil containing protein 3 (FGFR3-TACC3), which has been identified in many cancers such as glioblastoma and bladder cancer, is a potent oncogenic fusion protein that induces constitutive activation of FGFR signaling, resulting in uncontrolled cell proliferation.
Norihito, Shibata, Nobuo, Cho, Hiroo, Koyama, Mikihiko, Naito   +3 more
openaire   +2 more sources

Pediatric Acute Megakaryoblastic Leukemia: Multitasking Fusion Proteins and Oncogenic Cooperations

Trends in Cancer, 2017
Pediatric leukemia presents specific clinical and genetic features from adult leukemia but the underpinning mechanisms of transformation are still unclear. Acute megakaryoblastic leukemia (AMKL) is the malignant accumulation of progenitors of the megakaryocyte lineage that normally produce blood platelets. AMKL is diagnosed de novo, in patients showing
Cécile K, Lopez, Sébastien, Malinge, Muriel, Gaudry, Olivier A, Bernard, Thomas, Mercher   +4 more
openaire   +2 more sources

The immune response to oncogenic fusion proteins

2001
Chromosomal translocations represent somatically acquired cytogenetic mutations. When chromosomal breaks occur within exons of two different genes, the consequence of chromosomal translocation is the creation of a new fusion gene encoding for a chimeric protein.
Lorena Passoni, Carlo Gambacorti-Passerini   +1 more
openaire   +1 more source

Abl: the prototype of oncogenic fusion proteins.

Cellular and molecular life sciences : CMLS, 2004
Since it was first recognized, chronic myeloid leukemia (CML) has always represented a unique model to understand the molecular mechanisms underlying the onset and progression of a leukemic process. CML was the first recognized form of cancer to have a strong association with a recurrent chromosomal abnormality, the t(9;22) translocation, which ...
SAGLIO, Giuseppe, CILLONI, Daniela
openaire   +2 more sources

Abstract A68: Posttranslational modifications of the oncogenic fusion protein EWS/FLI1

Cancer Research, 2014
Abstract Ewing sarcoma is a pediatric tumor that affects bone and soft tissues. It is characterized in the majority of cases by the presence of a chromosomal translocation that leads to the expression of the oncogenic transcription factor, EWS/FLI1.
Laura A. Lopez Garcia, Maria E. Gierisch, Beat W. Schäfer   +2 more
openaire   +1 more source

The oncogenic fusion protein EWS/NOR-1 induces transformation of CFK2 chondrogenic cells

Experimental Cell Research, 2004
The EWS/NOR-1 fusion protein is encoded by the t(9;22) chromosomal translocation found in approximately 75% of extraskeletal myxoid chondrosarcoma (EMC) tumors. The lack of cellular models in which the oncogenic properties of this fusion protein are expressed has seriously hampered the study of its role in the development of EMC.
Christine, Filion, Yves, Labelle
openaire   +2 more sources