Results 161 to 170 of about 384,141 (378)

The proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL

, 2022
Johanna Stachelscheid, Qu Jiang, Christoph Markus Aszyk, Kathrin Warner, Nadine Bley, Tony Andreas Müller, Olga Vydzhak, Konstantinos Symeonidis, Giuliano Crispatzu, Petra Mayer, Stuart J. Blakemore, Gudrun Goehring, Sebastian Newrzela, Stephanie Hippler, Sandra Robrecht, Karl‐Anton Kreuzer, Christian P. Pallasch, Marcus Krüger, Axel Lechner, Kirsten Fischer, Stephan Stilgenbauer, Dirk Beutner, Michael Hallek, Daniel Auguin, Stefan Hüttelmaier, Johannes Bloehdorn, Elena Vasyutina, Marco Herling   +27 more
openalex   +2 more sources

Oncogenic osteomalacia [PDF]

QJM: An International Journal of Medicine, 2018
Annamalai, AK, Gill, AJ, Shinto, A, Sivakumar, R, Singhi, PK, Prabhu, VA, Gopalakrishnan, C, Chelian, M, Sridhar, S, Shanthi, R, Puri, V, Gururaj, N, Srinivasan, KG, Clifton-Bligh, R, Gurnell, M   +14 more
openaire   +2 more sources

RAS oncogenes: weaving a tumorigenic web

Nature Reviews. Cancer, 2011
Y. Pylayeva-Gupta, Elda Grabocka, D. Bar-Sagi   +2 more
semanticscholar   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Structure, chromosome location, and expression of the mouse zinc finger gene Krox-20: multiple gene products and coregulation with the proto-oncogene c-fos.

, 1989
Philippe Chavrier, U Janssen-Timmen, Marie‐Geneviève Mattéi, Marino Zerial, R Bravo, Patrick Charnay   +5 more
openalex   +2 more sources

Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells

Cell, 2009
C. Mayr, D. Bartel
semanticscholar   +1 more source

Integrative Approaches for DNA Sequence‐Controlled Functional Materials

Advanced Functional Materials, EarlyView.
DNA is emerging as a programmable building block for functional materials with applications in biomimicry, biochemical, and mechanical information processing. The integration of simulations, experiments, and machine learning is explored as a means to bridge DNA sequences with macroscopic material properties, highlighting current advances and providing ...
Aaron Gadzekpo, Ewa Anna Oprzeska‐Zingrebe, Mariana Kozlowska, Lennart Hilbert, Iliya D. Stoev   +4 more
wiley   +1 more source

Clinico-genomic findings, molecular docking, and mutational spectrum in an understudied population with breast cancer patients from KP, Pakistan

Frontiers in Genetics
In this study, we report the mutational profiles, pathogenicity, and their association with different clinicopathologic and sociogenetic factors in patients with Pashtun ethnicity for the first time. A total of 19 FFPE blocks of invasive ductal carcinoma
Hilal Ahmad, Asif Ali, Asif Ali, Asif Ali, Ali Talha Khalil, Roshan Ali, Ishaq Khan, Mah Muneer Khan, Ibrar Ahmed, Ibrar Ahmed, Zarrin Basharat, Mohammed Alorini, Amna Mehmood   +12 more
doaj   +1 more source

Molecular genetics of development studied in the transgenic mouse. [PDF]

, 1989
Gruss, P., Westphal, H.
core   +2 more sources