Results 251 to 260 of about 165,865 (302)
Single Nucleotide Polymorphism Microarray Analysis Unveils Copy-Number Abnormalities and Genetic Heterogeneity in Malaysian Childhood B-Cell Precursor Acute Lymphoblastic Leukemia. [PDF]
Mohd Dali NS +12 more
europepmc +1 more source
Transposons disrupt genomic stability and trigger cancers. [PDF]
Dong W, Li M, Li P, Hou X, He F, Ji S.
europepmc +1 more source
Pan-cancer inference and validation of hypermorphic, hypomorphic and neomorphic mutations. [PDF]
Tagore S +6 more
europepmc +1 more source
Editorial Expression of Concern: Co-encapsulation of HNF4α overexpressing UMSCs and human primary hepatocytes ameliorates mouse acute liver failure. [PDF]
Kong D +8 more
europepmc +1 more source
Factores de riesgo de cáncer bucal
Pedro Antonio Miguel Cruz +3 more
doaj
Oncogenes, Proto-Oncogenes, and Lineage Restriction of Cancer Stem Cells [PDF]
In principle, an oncogene is a cellular gene (proto-oncogene) that is dysfunctional, due to mutation and fusion with another gene or overexpression. Generally, oncogenes are viewed as deregulating cell proliferation or suppressing apoptosis in driving ...
Geoffrey Brown, Brown Geoffrey
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Lancet, The, 1984
A barrage of information is now emerging about one of the thorniest and most significant problems in biology: the nature of the genetic events that trigger neoplasia. While the notion that cancer reflects somatic mutations is several decades old, only in the last few years could the relevant 'oncogenes' be identified and put to molecular dissection ...
C J Marshall
exaly +5 more sources
A barrage of information is now emerging about one of the thorniest and most significant problems in biology: the nature of the genetic events that trigger neoplasia. While the notion that cancer reflects somatic mutations is several decades old, only in the last few years could the relevant 'oncogenes' be identified and put to molecular dissection ...
C J Marshall
exaly +5 more sources
Journal of Cellular Physiology, 1983
The discovery that normal cells contain proto-oncogenes--genes that are analogous to known viral oncogenes--may provide a shortcut not only to understanding some of the pathophysiologic mechanisms that must be involved in carcinogenesis but also to dissecting the processes of normal cell growth and of the evolutionarily developed controls on such ...
openaire +3 more sources
The discovery that normal cells contain proto-oncogenes--genes that are analogous to known viral oncogenes--may provide a shortcut not only to understanding some of the pathophysiologic mechanisms that must be involved in carcinogenesis but also to dissecting the processes of normal cell growth and of the evolutionarily developed controls on such ...
openaire +3 more sources

