Results 221 to 230 of about 137,458 (285)

HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
HOXB4 is overexpressed in bladder cancer and associated with poor prognosis. By transcriptionally activating Smoothened (SMO), HOXB4 amplifies SMO–GLI signaling to promote tumor growth and metastatic behavior. This graphical abstract highlights the HOXB4–SMO axis as a key driver of bladder cancer progression and a potential target for future ...
Zhaoheng Jin, Wenjie Yang, Yueqiang Peng, Lin Ma, Ziyi Li, Jie Dong, Zhigang Ji   +6 more
wiley   +1 more source

Infection-Induced Telomere Length Variation: Insights into Pathogenesis of Koala Retrovirus. [PDF]

Viruses
Cheung HM, Lin SWJ, Nguyen HTH, Stephenson T, Speight N, Hemmatzadeh F.   +5 more
europepmc   +1 more source

Decoding UTROSCT heterogeneity: systematic clinicopathological evaluation combined with molecular profiling

The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract Uterine tumor resembling ovarian sex cord tumor (UTROSCT) constitutes an exceptionally rare histological subset of uterine mesenchymal neoplasms. While most cases have benign clinical behavior, a subset of UTROSCTs exhibits clinically aggressive behavior characterized by recurrence and metastasis.
Jing Yang, Jinku Zhang, Jinmei Li, Yan Liu, Yuxiang Wang, Ajin Hu, Congrong Liu   +6 more
wiley   +1 more source

Convergent Mechanisms in Virus-Induced Cancers: A Perspective on Classical Viruses, SARS-CoV-2, and AI-Driven Solutions. [PDF]

Infect Dis Rep
Rudroff T.
europepmc   +1 more source

Epigenetic similarity between adenoid ameloblastoma and dentinogenic ghost cell tumour: DNA methylation analysis in odontogenic tumours

The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract Although adenoid ameloblastoma (AA) has recently been included in the WHO classification as a separate tumour type, its clinical, histological, immunohistochemical, and molecular similarities to dentinogenic ghost cell tumour (DGCT) raise questions about the current classification system. The aim of this study was to investigate the epigenetic
Kyu‐Young Oh
wiley   +1 more source

Human papillomavirus partial L2 gene variants in the Barrett's metaplasia-dysplasia-adenocarcinoma sequence. [PDF]

Microbiol Resour Announc
Rajendra K, Khabiri A, Rajendra S, Rabiei M.   +3 more
europepmc   +1 more source

DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer

Advanced Science, Volume 13, Issue 3, 14 January 2026.
In pancreatic cancer, the protein DKK3 is found to play a complex role: it initially slows early tumor growth but later promotes tumor aggressiveness. DKK3 expression evolves during progression and drives cancer severity by orchestrating cellular and molecular signaling pathways.
Dharini Srinivasan, Elodie Roger, Lukas Perkhofer, Eleni Zimmer, Thomas F.E. Barth, Julia P. Mosler, Anna Härle, Stephanie E. Weissinger, Nadine T. Gaisa, Peter Möller, Nico Fischer, Chantal Allgöwer, J.‐Matthias Löhr, Dirk Grimm, Thomas Seufferlein, Stefan Liebau, Ninel Azoitei, Michael K. Melzer, Frank Arnold, Johann Gout, Alexander Kleger   +20 more
wiley   +1 more source

Genetic mutations in lymphocytic variant of hypereosinophilic syndrome: study of five siblings. [PDF]

Front Med (Lausanne)
Walkenhorst M, Basu MK, Cui W, Kumar M, Vallurupalli A, Sitek A, Zhao X, Zheng XL, Zhang D.   +8 more
europepmc   +1 more source

Cancer Immunotherapy via Disruption of Integrin αvβ3 and CD47 Costabilization on Cancer Cell Surface

Advanced Science, Volume 13, Issue 2, 9 January 2026.
This study identifies a cancer‐specific interaction between CD47 and integrin αvβ3 that facilitates immune evasion. A rationally designed peptide, PSFL‐NK13, disrupts this axis, enhancing macrophage‐mediated phagocytosis and suppressing tumor growth without inducing anemia.
Peng‐Cheng Yu, Chen‐Xi Yue, Wen‐Zhong Dong, Cui‐Yun Hao, Yi‐Fan Qiao, Di Liu, Xin Zhang, Qi Zhan, Jia‐Bao Yao, Dong‐Ping Wang, Peng Cao, Ying‐Zhe Fan, Ye Yu   +12 more
wiley   +1 more source

Molecular Characterization of Polyomavirus-Positive and Negative Merkel Cell Carcinoma. [PDF]

Cancers (Basel)
Vaidya P, Wu S, Bryant D, Perry CJ, Prakash V, Lou E, Guo T, Brownell I, Darabi S, Gao L, Abdulla F, Park SJ.   +11 more
europepmc   +1 more source