Results 131 to 140 of about 41,863 (260)

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff   +6 more
wiley   +1 more source

Role of Virally Encoded Circular RNAs in the Pathogenicity of Human Oncogenic Viruses. [PDF]

open access: yesFront Microbiol, 2021
Avilala J   +6 more
europepmc   +1 more source

Enhancing Optogenetics‐Based Cancer Therapy Via Nanotechnology

open access: yesExploration, EarlyView.
Nanotechnology enhances optogenetics‐based cancer therapy through improved delivery systems and non‐invasive optical regulation. It further enables precise and programmable control of optogenetic living therapeutics for localized antitumor responses.
Honggang Shen   +8 more
wiley   +1 more source

Disease Site‐Specific Outcomes in p16‐Positive Non‐Oropharyngeal Mucosal Head and Neck Cancer

open access: yesHead &Neck, EarlyView.
ABSTRACT Objectives To report disease‐free survival (DFS) in p16‐positive non‐oropharyngeal head‐and‐neck squamous‐cell carcinoma (HNSCC). Methods Curatively‐treated non‐oropharyngeal HNSCC (2009–2021) were reviewed. DFS was compared among p16‐positive, p16‐negative, and p16‐untested cases for the overall cohort and by disease site.
Revadhi C. Chelvarajah   +21 more
wiley   +1 more source

Tumour Viruses [PDF]

open access: yes, 2016
Current worldwide estimates suggest that approxiamtely 11% of all cancers are caused by viral infections. At present, there are eight viruses that have a strong association with cancer development namely, human papillomavirus, Epstein-Barr virus, Kaposi ...

core  

Human DNA oncogenic viruses and their transforming protein interactions with cell cycle control proteins

open access: yes, 1999
Purpose Both oncogenic viruses and cell cycle control proteins are fast-growth research areas. More and more evidence indicates that virus infection and replication are often associated with apoptosis and interfere with cell cycle pathways. To understand
Cheng, Y
core   +1 more source

Influenza and Human Papillomavirus Vaccine Utilisation in Vulnerable Urban Youth in Edmonton, Alberta, Canada

open access: yesThe International Journal of Health Planning and Management, EarlyView.
ABSTRACT Introduction This project explores influenza and human papillomavirus (HPV) vaccine utilisation among a multi‐ethnic group of youth (aged 11–23 years) in Edmonton, Alberta, Canada. Method Using a cross‐sectional design and purposive sampling, influenza vaccine utilisation over 3 years was assessed via questionnaire.
Sarah Deck   +5 more
wiley   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

open access: yesInternational Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia   +4 more
wiley   +1 more source

Availability of Cancer Screening Across HIV Treatment Sites in the IeDEA Consortium

open access: yesInternational Journal of Cancer, EarlyView.
In recent years, incorporating comprehensive cancer screening strategies into routine HIV care has gained growing attention. This survey of 220 sites providing HIV care across 41 countries shows that cervical cancer screening has increased in availability over time.
Rachael A. Pellegrino   +32 more
wiley   +1 more source

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