Results 41 to 50 of about 41,863 (260)

Oncogenic Viruses in Skull Base Chordomas [PDF]

, 2018
BACKGROUND: Chordomas are rare tumors assumed to derive from notochordal remnants. We believe that a molecular switch is responsible for their malignant behavior. The involvement of oncogenic viruses has not been studied, however.
Yakkioui, Youssef, Wolffs, Petra F. G., Jacobus J. Van Overbeeke, Sreedhar Pujari, Merel J.M. Boderie, Boderie, Merel J. M., Van Overbeeke, Jacobus J., Speel, Ernst-Jan M., Temel, Yasin, Ernst-Jan M. Speel, Yasin Temel, Pujari, Sreedhar, Hausen, Axel Zur, Youssef Yakkioui, Axel Zur Hausen, Petra F.G. Wolffs   +15 more
core   +1 more source

Insight into Oncogenic Viral Pathways as Drivers of Viral Cancers: Implication for Effective Therapy

Current Oncology, 2023
As per a recent study conducted by the WHO, 15.4% of all cancers are caused by infectious agents of various categories, and more than 10% of them are attributed to viruses.
Ahmed M. E. Elkhalifa, Showkat Ul Nabi, Ovais Shabir Shah, Showkeen Muzamil Bashir, Umar Muzaffer, Sofi Imtiyaz Ali, Imtiyaz Ahmad Wani, Nasser A. N. Alzerwi, Abozer Y. Elderdery, Awadh Alanazi, Fawaz O. Alenazy, Abdulaziz Hamdan A. Alharbi   +11 more
doaj   +1 more source

Oncogenic DNA viruses [PDF]

Oncogene, 2001
The early discoveries of Gross (1951) of viral causation of murine leukemias, the subsequent demonstration of retroviruses as the causative factors and the presence of similar viruses particularly in lymphoproliferative disorders in cattle, cats, and various rodent species, underlined for decades the justi®cation of attempts to search for similar ...
openaire   +2 more sources

Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers

, 2021
Human herpesviruses are known to induce a broad spectrum of diseases, ranging from common cold sores to cancer, and infections with some types of these viruses, known as human oncogenic herpesviruses (HOHVs), can cause cancer.
Miroslava Šudomová, Alena Liskova, Peter Kubatka, Kateřina Berchová-Bímová, Sherif Hassan, Stefania Marzocco   +5 more
core   +1 more source

Developing a virus-microRNA interactome using cytoscape

MethodsX, 2020
It is currently difficult to determine the effect of oncogenic viruses on the global function and regulation of pathways within mammalian cells. A thorough understanding of the molecular pathways and individual genes altered by oncogenic viruses is ...
Meredith Hill, Dayna Mason, Tânia Monteiro Marques, Margarida Gama Carvalho, Nham Tran   +4 more
doaj   +1 more source

Putative oncogenic viruses : some data on Brazilian subjects [PDF]

, 2021
The concepts of cancer etiology have changed over the years, mainly based on molecular epidemiology studies and bioinformatics approaches. Until relatively recently, the most accepted theory of cancer etiology has dealt with the accumulation of gene ...
Rocha, Sheyla A. S., Mansour, Munnah N. J., Bretas, Isadora S., Bernardes, João P. R. A., Napoleão, Sarah M. S., Sampaio, Thatiane L., Tenório, Bernardo G., Leitão, Elisiário C. V., Coimbra, Marcus V. S., Bello, Edson J. M., Silva, Joaquim X., Kanzaki, Luis Isamu Barros, Kanzaki, Elida C. G. M.   +12 more
core   +1 more source

Improved assembly procedure of viral RNA genomes amplified with Phi29 polymerase from new generation sequencing data

Biological Research
BACKGROUND: New sequencing technologies have opened the way to the discovery and the characterization of pathogenic viruses in clinical samples. However, the use of these new methods can require an amplification of viral RNA prior to the sequencing ...
Nicolas Berthet, Stéphane Descorps-Declère, Andriniaina Andy Nkili-Meyong, Emmanuel Nakouné, Antoine Gessain, Jean-Claude Manuguerra, Mirdad Kazanji   +6 more
doaj   +1 more source

Exploring the link between viruses and cancer in companion animals: a comprehensive and comparative analysis

Infectious Agents and Cancer, 2023
Currently, it is estimated that 15% of human neoplasms globally are caused by infectious agents, with new evidence emerging continuously. Multiple agents have been implicated in various forms of neoplasia, with viruses as the most frequent.
Francesca Parisi, Niccolò Fonti, Francesca Millanta, Giulia Freer, Mauro Pistello, Alessandro Poli   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source