Results 31 to 40 of about 22,177 (184)

Predicting Different Recurrence Risk in HNSCC Using Circulating Inflammatory and T‐Cell Biomarkers

The Laryngoscope, EarlyView.
ABSTRACT Objective Head and neck squamous cell carcinoma (HNSCC) lacks reliable prognostic circulating biomarkers, and the role of the immune system in its progression remains incompletely understood. This study aimed to evaluate the prognostic value of systemic inflammatory and immune biomarkers in surgically treated patients with primary oral cavity (
Riccardo Gili, Paola Lovino Camerino, Luca Lalli, Elisa Bellini, Chiara Tagliaferri, Filippo Bruno Lanza, Stefania Vecchio, Simone Caprioli, Giorgio Peretti, Lucia Del Mastro, Filippo Marchi   +10 more
wiley   +1 more source

Dynamic Profiling of Circulating Tumor Cells and MYC/PTEN Alterations in Prostate Cancer Patients Undergoing Radical Prostatectomy in Amazon Population

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed malignancy among men and the sixth leading cause of cancer‐related mortality worldwide. Radical prostatectomy remains the standard treatment for localized disease; however, approximately one‐third of patients develop biochemical recurrence within 10 years. Although prostate‐specific
Juliana Ramos Chaves, Rommel Mario Rodriguez Burbano, Amanda de Nazaré Cohen‐Paes, Diego Di Felipe Ávila Alcântara, Ana Paula Borges de Souza, Maria Janete Nahum Gomes, Sérgio Augusto Antunes Ramos, André Salim Khayat   +7 more
wiley   +1 more source

Tributyltin Protumorigenic Effects Targeting Prostate Cancer Cell Metabolism, Proliferation, Migration, and Invasion

Environmental Toxicology, EarlyView.
ABSTRACT Prostate cancer (PCa) is an endocrine‐related cancer highly dependent on androgenic signaling. Beyond hormone dependence, extrinsic factors play a significant role in the risk of developing PCa, which raises concern about the influence of environmental compounds such as endocrine‐disrupting chemicals (EDCs). Tributyltin (TBT) is an EDC used in
Mariana Feijó, Luís P. Brás, Catarina M. D. Serra, Lara R. S. Fonseca, Sara Correia, Bruno J. Pereira, Ana P. Duarte, Henrique J. Cardoso, Cátia V. Vaz, Sílvia Socorro   +9 more
wiley   +1 more source

Pre‐clinical validation of a selective anti‐cancer stem cell therapy for Numb‐deficient human breast cancers

EMBO Molecular Medicine, 2017
The cell fate determinant Numb is frequently downregulated in human breast cancers (BCs), resulting in p53 inactivation and an aggressive disease course.
Daniela Tosoni, Sarah Pambianco, Blanche Ekalle Soppo, Silvia Zecchini, Giovanni Bertalot, Giancarlo Pruneri, Giuseppe Viale, Pier Paolo Di Fiore, Salvatore Pece   +8 more
doaj   +1 more source

Timoma em cão: Relato de Caso

Pubvet, 2021
Timoma é um tumor que surge a partir de células do timo, um órgão presente em todos os mamíferos e responsável pela maturação de linfócitos T, que regride de tamanho ao longo da vida, até que na idade adulta é gradualmente substituído por tecido adiposo.
Taine Elia de Oliveira, Paula Papareli de Oliveira, Elisangela Guedes Duarte, Carolina Vianna Leite Otero, Verônica Garcez Araújo, Bruno De Tullio Augusto Roque Lima   +5 more
doaj   +1 more source

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source

Semen Cryopreservation in Testicular Cancer: Before or After Orchidectomy?

Andrology, EarlyView.
ABSTRACT Background Fertility preservation in patients with testicular cancer remains a clinical priority, yet the optimal timing for sperm cryopreservation—before or after orchidectomy—remains a matter of debate. Objectives The aim of this study was to determine the optimal timing for semen cryopreservation and the best‐quality sample for ART.
Alessandra Buonacquisto, Carlotta Pozza, Gaia Cicolani, Anna Chiara Conflitti, Luisa Caponecchia, Serena Bianchini, Enrico Delli Paoli, Marta Tenuta, Daniele Gianfrilli, Andrea M. Isidori, Francesco Lombardo, Francesco Pallotti, Donatella Paoli   +12 more
wiley   +1 more source

A COMPLEX CARE: COMMUNICATING BAD NEWS IN ONCOLOGY

Revista de Pesquisa Cuidado é Fundamental Online, 2012
Objetivos: Analisar as produções científicas que abordam a temática de más notícias em oncologia e discutir a comunicação das mesmas nesta área. Método: Trata-se de uma revisão bibliográfica de abordagem qualitativa.
Raquel de Abreu Pinheiro e Souza, Sônia Regina de Souza   +1 more
doaj   +1 more source

Nationwide Implementation of Double Reflex Testing for Hepatitis Delta in Spain: Results From the Retrospective Phase of the Spain‐DDR Study

Alimentary Pharmacology &Therapeutics, EarlyView.
Nationwide implementation of double reflex testing for hepatitis delta in Spain markedly increased anti‐HDV and HDV viral load testing between 2022 and 2024, enabling national seroprevalence estimates. Despite this progress, substantial regional heterogeneity persists, highlighting the need for standardised reflex diagnostic protocols.
Ana Alberola, Adolfo de Salazar, Ana Fuentes, Raquel Carracedo, Marta Illescas‐López, María del Carmen Rodríguez Baños, Carolina Freyre, Berta Becerril, Isabel Viciana, Inmaculada López‐Rodríguez, Natalia Montiel, Ana María Domínguez Castaño, María Pilar Luzón‐García, Encarnación Ramírez Arellano, Carmen Liébana‐Martos, Francisco Franco Álvarez de Luna, María del Carmen Lozano, Begoña Palop, Antonio Sampedro, Ana Belén Pérez, Sonia Algarate, Susana Rojo Alba, Pablo Fraile, Dolores Ocete, María Jesús Alcaraz, Juan Carlos Rodríguez, Francisco Javier Hernández‐Felices, Olalla Martínez, Victoria Domínguez, Nieves Orta, Dolores Gómez, Carmen Cortell, Jorge Camacho, Susana Sabater, Luis Ángel Iglesias Sánchez, Yasmina Martín, Aldara Vallejo, Lourdes Molina, María Aroca, Beatriz Castro, Magdalena Lara, María José Pena, Ana Rodríguez‐Fernández, Alejandro González Praetorius, José Joaquín Blas, Alicia Beteta, César Gómez, María José Rodríguez, Soledad Illescas, Melanie Abreu, Julio García Díez, Inocencio Beltrán, Marta Sandoval Torrientes, Ruth Sáez, Teresa Martín, Pilar Tajada Alegre, Belén Lorenzo, María Teresa García Valero, Isabel Jiménez Sansegundo, Susana García‐de Cruz, Sonsoles Garcinuño, Miguel Ángel Sáiz, Santiago Muñoz, Isabel Fernández, Helena Miriam Lorenzo Juanes, María Reyes Vidal‐Acuña, Luz María Moldes, Noelia Calvo, Matilde Trigo, María José Gude, Patricia Ordóñez, Sandra Cortizo, Miriam Blasco, Mayra Sigcha, Iker Falces, Juan Carlos Galán, Ana Arribi, Roberto Alonso, Asunción Iborra, María Jesús del Amor Espín, Eva Cascales, Cayetano Pérez, Pablo Fernández, María Dolores Navarro, María Luz Nuñez, Jorge Galán Ros, Luis Javier Gil‐Gallardo, Ana Miqueleiz, Gabriel Reina, Luis Elorduy, Mikele Macho, Carmen Gómez, Paloma Liendo, Yolanda Salicio, Antonio Aguilera, Federico García   +95 more
wiley   +1 more source

Immunoprofiling, sex‐ and age‐related determinants of treatment response in paediatric, adolescent and young adult Hodgkin lymphoma

British Journal of Haematology, EarlyView.
Multimodal integration of sex‐ and age‐related immune‐gene signatures with baseline tumor burden (TMTV1) improves prediction of treatment response in adolescents and young adults with classical Hodgkin lymphoma. Summary The study investigates how sex and age influence treatment response in paediatric, adolescent and young adult (AYA) classical Hodgkin ...
Valli De Re, Egesta Lopci, Giulia Brisotto, Caterina Elia, Angelo Vitullo, Veronica Paduano, Mariangela De Zorzi, Lara Mussolin, Paola Quarello, Simona Bianchi, Salvatore Buffardi, Alberto Garaventa, Paola Muggeo, Marta Pillon, Alessandra Sala, Luciana Vinti, Emanuele d'Amore, Christine Mauz‐Korholz, Maurizio Mascarin, on behalf of the AIEOP Hodgkin's Lymphoma Study Group, Alberto Garaventa, Alessandra Sala, Antonella Sau, Assunta Tornesello, Daniela Galimberti, Domenico Sperlì, Elena Facchini, Eulalia Galea, Federico Verzegnassi, Fiorina Giona, Francesca Rossi, Fulvio Porta, Irene D’Alba, Katia Perruccio, Luciana Vinti, Marco Zecca, Marta Pillon, Massimo Provenzi, Maurizio Bianchi, Maurizio Mascarin, Monica Cellini, Nadia Vacca, Paola Muggeo, Patrizia Bertolini, Piero Farruggia, Raffaella De Santis, Roberta Pericoli, Rosamaria Mura, Salvatore Buffardi, Salvatore D’Amico, Sayla Bernasconi, Simona Rinieri, Simone Cesaro, Tommaso Casini, Valerio Cecinati   +54 more
wiley   +1 more source