Results 61 to 70 of about 48,900 (212)

Unlocking the power of immune checkpoint inhibitors: Targeting YAP1 reduces anti‐PD1 resistance in skin cutaneous melanoma

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Immune checkpoint inhibitors, such as anti­PD1, revolutionized melanoma treatment. However, resistance and low response rates remain problems. Our goal was to pinpoint actionable biomarkers of resistance to anti‐PD1 treatment and verify therapeutic effectiveness in vivo.
Szonja Anna Kovács   +13 more
wiley   +1 more source

Neuropsychology and Oncology: an emerging dialogue

open access: yesInteração em Psicologia, 2016
Dados do INCA estimam que anualmente cerca de 11.530 casos de neoplasias são diagnosticados em crianças e adolescentes. O aumento do número de sobreviventes vem crescendo, junto com as sequelas cognitivas decorrentes da doença e de seu tratamento.
Izabel Hazin   +4 more
doaj   +1 more source

Automated detection of lung nodules in low-dose computed tomography [PDF]

open access: yes, 2007
A computer-aided detection (CAD) system for the identification of pulmonary nodules in low-dose multi-detector computed-tomography (CT) images has been developed in the framework of the MAGIC-5 Italian project. One of the main goals of this project is to
Cascio, D.   +13 more
core   +2 more sources

Tumor‐related epilepsy in glioma: A multidisciplinary overview

open access: yesEpilepsia, EarlyView.
Abstract Seizures are a common and challenging symptom in brain tumors, affecting approximately 60% of patients. Tumor‐related epilepsy (TRE) in glioma patients requires personalized and dynamic management in a multidisciplinary environment, especially for its intricate pathophysiology and unpredictable disease evolution. This investigation provides an
Roberto Michelucci   +29 more
wiley   +1 more source

Neoplasias de língua em cinco cães Neoplasms of the tongue in five dogs

open access: yesCiência Rural, 2007
Este trabalho tem como objetivo relatar a ocorrência de cinco casos de neoplasias de língua em cães. Os sinais clínicos mais observados foram ptialismo, halitose e hiporexia.
Carlos Roberto Daleck   +4 more
doaj   +1 more source

Efficacy and safety of T-DM1 in the 'common-practice' of HER2+ advanced breast cancer setting: a multicenter study [PDF]

open access: yes, 2017
Ado-trastuzumab emtansine (T-DM1) is an antibody-drug conjugate approved for the treatment of patients with human epidermal growth factor receptor 2 (HER2)-positive, metastatic breast cancer (mBC).
Alesini, Daniele   +27 more
core   +1 more source

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

open access: yesThe FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés   +19 more
wiley   +1 more source

Linfossarcoma intracerebral em bovino Intracerebral lymphosarcoma in a cow

open access: yesCiência Rural, 2004
Relata-se um caso de linfossarcoma intracerebral em uma vaca holandesa de 2 anos e meio que apresentou cegueira, embotamento e anosmia por duas semanas. O soro deste bovino testou positivo para anticorpos contra o vírus da leucose bovina.
Rafael Almeida Fighera   +1 more
doaj   +1 more source

A humanização das salas de quimioterapia pediátricas do Rio de Janeiro : o hospital pelo olhar da criança [PDF]

open access: yes, 2007
A área de investimento em Oncologia Pediátrica do Instituto Desiderata tem por missão contribuir com a melhoria das condições de tratamento e cura do câncer infanto-juvenil.Esta publicação tem por objetivo registrar o rico processo de reflexão sobre as ...
Martha Cristina Nunes Moreira   +1 more
core  

Luspatercept for Transfusion‐Dependent Beta‐Thalassemia: Real‐World Experience in a Large Cohort of Patients From Italy

open access: yes
American Journal of Hematology, EarlyView.
Raffaella Origa   +36 more
wiley   +1 more source

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