Results 21 to 30 of about 1,640,336 (314)

An overview and a roadmap for artificial intelligence in hematology and oncology

Journal of Cancer Research and Clinical Oncology, 2023
Artificial intelligence (AI) is influencing our society on many levels and has broad implications for the future practice of hematology and oncology. However, for many medical professionals and researchers, it often remains unclear what AI can and cannot
Wiebke Rösler, M. Altenbuchinger, B. Baessler, T. Beissbarth, G. Beutel, R. Bock, N. von Bubnoff, Jan-Niklas Eckardt, S. Foersch, C. Loeffler, J. Middeke, Martha Mueller, T. Oellerich, Benjamin Risse, A. Scherag, C. Schliemann, M. Scholz, R. Spang, C. Thielscher, I. Tsoukakis, Jakob Nikolas Kather   +20 more
semanticscholar   +1 more source

Oncologic Outcomes of a Novel Mapping Biopsy Technique Before Surgical Excision in the Management of Extramammary Paget Disease

Société Internationale d’Urologie Journal, 2023
ObjectiveTo analyze oncologic outcomes of patients with extramammary Paget disease (EMPD) undergoing a novel mapping biopsy before tumor excision (WLE). MethodsWe analyzed 19 consecutive patients with EMPD treated with biopsy and/or surgical excision at
Kyle M. Rose , Rosalie Zurlo , Roger Li , Gerard Mosiello, Philippe E. Spiess   +4 more
doaj   +1 more source

IOBR: Multi-Omics Immuno-Oncology Biological Research to Decode Tumor Microenvironment and Signatures

bioRxiv, 2020
Motivation Recent advance in next generation sequencing has triggered the rapid accumulation of publicly available multi-omics datasets. The application of integrated omics to exploring robust signatures for clinical translation is increasingly ...
D. Zeng, Zilan Ye, Guangchuang Yu, Jiani Wu, Yi Xiong, R. Zhou, Wenjun Qiu, N. Huang, Li Sun, J. Bin, Y. Liao, Min Shi, W. Liao   +12 more
semanticscholar   +1 more source

Radiomics in Oncology: A Practical Guide

Radiographics, 2021
Radiomics refers to the extraction of mineable data from medical imaging and has been applied within oncology to improve diagnosis, prognostication, and clinical decision support, with the goal of delivering precision medicine.
J. Shur, S. Doran, Santosh Kumar, Derfel Ap Dafydd, K. Downey, J. O’Connor, N. Papanikolaou, C. Messiou, D. Koh, M. Orton   +9 more
semanticscholar   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Accelerating patient access to oncology medicines with multiple indications in Europe

Journal of Market Access & Health Policy, 2021
Background: In recent years, innovation in oncology has created new challenges for pricing and reimbursement systems. Oncology medicines with multiple indications face a number of access challenges: (1) the number of assessments and administrative burden;
R. Lawlor, T. Wilsdon, E. Darquennes, D. Hemelsoet, J. Huismans, R. Normand, A. Roediger   +6 more
doaj   +1 more source

Prospective Determination of Orbital Perfusion Dominance before Intra-Arterial Chemotherapy for Retinoblastoma Using Time-of-Flight Magnetic Resonance Angiography

Journal of Clinical Interventional Radiology ISVIR, 2023
Intra-arterial chemotherapy (IAC) represents a mainstay in the treatment of retinoblastoma. In a minority of cases, the external carotid artery (ECA) serves as the dominant supply to the central retinal artery and is associated with prolonged fluoroscopy
Eric J. Monroe, Jeffrey P. Otjen, Jason N. Wright, Francisco A. Perez, Jeffrey Forris Beecham Chick, Danial K. Hallam, Mark R. Ferguson   +6 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions.

Neuro-Oncology, 2020
Glioblastomas are the most common form of malignant primary brain tumor and an important cause of morbidity and mortality. In recent years there have been important advances in understanding the molecular pathogenesis and biology of these tumors, but ...
P. Wen, M. Weller, E. Lee, B. Alexander, J. Barnholtz-Sloan, F. Barthel, T. Batchelor, R. Bindra, Susan M. Chang, E. Chiocca, T. Cloughesy, J. Degroot, E. Galanis, M. Gilbert, M. Hegi, C. Horbinski, Raymond Y Huang, A. Lassman, É. Le Rhun, M. Lim, M. Mehta, I. Mellinghoff, G. Minniti, D. Nathanson, M. Plattén, M. Preusser, P. Roth, M. Sanson, D. Schiff, S. Short, M. Taphoorn, J. Tonn, J. Tsang, R. Verhaak, A. von Deimling, W. Wick, G. Zadeh, D. Reardon, K. Aldape, M. J. van den Bent   +39 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source