Results 161 to 170 of about 4,767 (196)

Vinorelbine enhances the efficacy of GM-CSF-armed oncolytic vaccinia virus in a preclinical model of ovarian high grade serous carcinoma

Drymiotou S, Queval CJ, Tyson KE, Sheach LA, Postigo A, Rosa ID, Ennis DP, Howell M, McNeish IA, Way M.   +9 more
europepmc   +1 more source

Histone deacetylase inhibitor boosts anticancer potential of fusogenic oncolytic vaccinia virus by enhancing cell-cell fusion. [PDF]

Cancer Sci
Nakatake M, Kurosaki H, Nakamura T.
europepmc   +1 more source

Intratumoral Delivery of Interleukin 9 via Oncolytic Vaccinia Virus Elicits Potent Antitumor Effects in Tumor Models. [PDF]

Cancers (Basel)
Ye J, Chen L, Waltermire J, Zhao J, Ren J, Guo Z, Bartlett DL, Liu Z.   +7 more
europepmc   +1 more source

A new MVA ancestor-derived oncolytic vaccinia virus induces immunogenic tumor cell death and robust antitumor immune responses. [PDF]

Mol Ther
Rojas JJ, Van Hoecke L, Conesa M, Bueno-Merino C, Del Canizo A, Riederer S, Barcia M, Brosinski K, Lehmann MH, Volz A, Saelens X, Sutter G.   +11 more
europepmc   +1 more source

Oncolytic vaccinia virus armed with 4-1BBL elicits potent and safe antitumor immunity and enhances the therapeutic efficiency of PD-1/PD-L1 blockade in a pancreatic cancer model. [PDF]

Transl Oncol
Ju Y, Dai F, Wang Y, Ye Z, Li Y, Ju S, Ge Y, Chen W.   +7 more
europepmc   +1 more source

TG6050, an oncolytic vaccinia virus encoding interleukin-12 and anti-CTLA-4 antibody, favors tumor regression via profound immune remodeling of the tumor microenvironment. [PDF]

J Immunother Cancer
Azar F, Deforges J, Demeusoit C, Kleinpeter P, Remy C, Silvestre N, Foloppe J, Fend L, Spring-Giusti C, Quéméneur E, Marchand JB.   +10 more
europepmc   +1 more source

PD-1 inhibitor plus oncolytic vaccinia virus is a safe and effective treatment option for metastatic renal cell carcinoma. [PDF]

Cancer Cell Int
Park JS, Lee ME, Kim J, Oh K, Lee N, Jung M, Jang WS, Ham WS.   +7 more
europepmc   +1 more source

Expression of GPX4 by oncolytic vaccinia virus can significantly enhance CD8⁺T cell function and its impact against pancreatic ductal adenocarcinoma. [PDF]

Oncoimmunology
Wei W, Tian L, Zheng X, Zhong L, Chen Y, Dong H, Zhang G, Wang S, Tong X.   +8 more
europepmc   +1 more source

Oncolytic Vaccinia virus and radiotherapy in head and neck cancer

Oral Oncology, 2013
Oncolytic forms of attenuated Vaccinia virus are now in clinical development, assessing the compatibility of this novel treatment with radiotherapy may reveal exploitable synergistic relationships.In vitro analyses of cell killing, cell cycle effects and caspase activation were carried out on HN3, HN5, CAL27, Detroit, SIHN5B, and PJ41 cells.
Mansfield, D, Pencavel, T, Kyula, JN, Zaidi, S, Roulstone, V, Thway, K, Karapanagiotou, L, Khan, AA, McLaughlin, M, Touchefeu, Y, Seth, R, Melcher, AA, Vile, RG, Pandha, HS, Harrington, KJ   +14 more
core   +6 more sources