Results 91 to 100 of about 37,893 (278)
Strategies in Gene Therapy for Glioblastoma [PDF]
, 2013 Glioblastoma (GBM) is the most aggressive form of brain cancer, with a dismal prognosis and extremely low percentage of survivors. Novel therapies are in dire need to improve the clinical management of these tumors and extend patient survival.
Behera, Prajna +4 more
core +2 more sources
New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
Rare Metals, EarlyView.ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
Overcoming tumor resistance by heterologous adeno-poxvirus combination therapy
Molecular Therapy: Oncolytics, 2014 Successful cancer control relies on overcoming resistance to cell death and on activation of host antitumor immunity. Oncolytic viruses are particularly attractive in this regard, as they lyse infected tumor cells and trigger robust immune responses ...
Markus Vähä-Koskela +16 more
doaj +1 more source
Molecular Therapy: Oncolytics, 2020 Oncolytic viruses can target neoplasms, triggering oncolytic and immune effects. Their delivery to melanoma lesions remains challenging. Bone-marrow-derived mesenchymal stem cells (MSCs) were shown to be permissive for oncolytic myxoma virus (MYXV ...
Joanna Jazowiecka-Rakus +9 more
doaj +1 more source
Novel Oncolytic Virus Armed with Cancer Suicide Gene and Normal Vasculogenic Gene for Improved Anti-Tumor Activity [PDF]
, 2020 Su-Nam Jeong, So Young Yoo
openalex +1 more source
Attenuated Semliki Forest virus for cancer treatment in dogs : safety assessment in two laboratory Beagles [PDF]
, 2015 Background: Dogs suffer from spontaneous tumors which may be amenable to therapies developed for human cancer patients, and dogs may serve as large-animal cancer models.
Anttila, Marjukka O. +7 more
core +1 more source
Neoadjuvant therapy in skin cancer: current evidence and future perspectives
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary The development of immune checkpoint inhibitors and targeted therapies has fundamentally changed the treatment of cutaneous malignancies, especially in squamous cell carcinoma, melanoma, and Merkel cell carcinoma. The latest neoadjuvant approaches have shown promising results in locally advanced stages.
Lea Daniello +2 more
wiley +1 more source
Molecular Therapy: Oncolytics, 2019 As a clinical setting in which novel treatment options are urgently needed, hepatocellular carcinoma (HCC) exhibits intriguing opportunities for oncolytic virotherapy.
Yong Luo +11 more
doaj +1 more source
Targeting the microbiota‐miRNA‐protease axis: A new therapeutic avenue in melanoma
The FEBS Journal, EarlyView.Modulation of extracellular matrix (ECM) turnover is central to melanoma progression and metastasis, driven largely by ECM proteases. This review highlights the epigenetic regulation of ECM proteases by microRNAs and their roles in melanoma growth, invasion, and immune modulation.
Elias N. Katsoulieris +2 more
wiley +1 more source
Mechanisms of measles virus oncolytic immunotherapy
Cytokine & Growth Factor Reviews, 2020 The study of measles virus (MeV) as a cancer immunotherapeutic was prompted by clinical observations of leukemia and lymphoma regressions in patients following measles virus infection in the 1970s and 1980s. Since then, numerous preclinical studies have confirmed the oncolytic activity of MeV vaccine strains as well as their potential to promote long ...
Gemma, Pidelaserra-Martí +1 more
openaire +2 more sources