Artificially cloaked viral nanovaccine for cancer immunotherapy
Cancer therapy using oncolytic virus has shown pre-clinical and clinical efficacy. Here, the authors report ExtraCRAd, an oncolytic virus cloaked with tumour cell membrane and report its therapeutic effects in vitro and in vivo in multiple mouse tumour ...
Manlio Fusciello+17 more
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Oncolytic Virus Therapy Using Genetically Engineered Herpes Simplex Viruses [PDF]
Tomoki Todo
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980. ICP34.5 Deleted Herpes Simplex Virus 1 with Enhanced Oncolytic and Anti-Tumour Properties: Preclinical Studies [PDF]
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TGF-β Inhibition Improves Oncolytic Herpes Viroimmunotherapy in Murine Models of Rhabdomyosarcoma
Oncolytic viruses are an emerging class of cancer therapeutics that couple cytotoxicity with the induction of an anti-tumor immune response. Host-virus interactions are complex and modulated by a tumor microenvironment whose immunosuppressive activities ...
Brian Hutzen+8 more
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Oncolytic viruses for the therapy of brain tumors and other solid malignancies a review [PDF]
E. Antonio Chiocca
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Newcastle disease virus (NDV) is a single-stranded, negative-sense RNA virus in the Paramyxoviridae family. Although primarily an avian pathogen, NDV is a potent oncolytic virus that has been shown to be safe and effective in a variety of preclinical ...
Lisa A. Santry+7 more
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746. Effective Therapy of Metastatic Ovarian Cancer with an Oncolytic Herpes Simplex Virus Incorporating Two Membrane-Fusion Mechanisms [PDF]
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326. Biodistribution of Oncolytic Recombinant Edmonston B Measles Virus in Measles-Susceptible Mice [PDF]
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1175. Oncolytic Herpes Simplex Virus-1 G207 Induces Cyclooxygenase-2 Gene Expression by Activation of the Mitogen Activated Protein Kinase Pathway [PDF]
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Oncolytic Semliki Forest virus (SFV) has been suggested as a potential candidate for the treatment of glioblastoma and neuroblastoma. However, the oncolytic capacity of SFV is restricted by the anti-viral type-I interferon (IFN) response. The aim of this
Tina Sarén+3 more
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