Enhancement of chemotherapy using oncolytic virotherapy: Mathematical and optimal control analysis
, 2018 Oncolytic virotherapy (OV) has been emerging as a promising novel cancer treatment that may be further combined with the existing therapeutic modalities to enhance their effects.
Eladdadi, Amina +4 more
core +1 more source
Oncolytic Adenovirus-Induced Autophagy: Tumor-Suppressive Effect and Molecular Basis [PDF]
, 2013 Autophagy is a catabolic process that produces energy through lysosomal degradation of intracellular organelles. Autophagy functions as a cytoprotective factor under physiological conditions such as nutrient deprivation, hypoxia, and interruption of ...
Fujiwara, Toshiyoshi +2 more
core +1 more source
Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy
Cancer Medicine, Volume 15, Issue 2, February 2026.ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li +13 more
wiley +1 more source
Last Year\u27s Virus, This Year\u27s Cancer Treatment [PDF]
, 2018 For hundreds of years, cancer has stumped medical professionals across the world as a cure evaded them. Now, a new approach to battling cancer has entered the arena: viruses.
Collins, Olivia
core +1 more source
Recent progress in combination therapy of oncolytic vaccinia virus
Frontiers in ImmunologyIn recent years, oncolytic viruses have emerged as promising agents for treating various cancers. An oncolytic virus is a non-pathogenic virus that, due to genetic manipulation, tends to replicate in and cause lysis of cancerous cells while leaving ...
Seyedeh Nasim Mirbahari +12 more
doaj +1 more source
The essential role of mitochondrial dynamics in antiviral immunity. [PDF]
, 2018 Viruses alter cellular physiology and function to establish cellular environment conducive for viral proliferation. Viral immune evasion is an essential aspect of viral persistence and proliferation.
Ahn, Dae-Gyun +3 more
core +2 more sources
Integrative Omics Analysis Reveals the Potential Value of CEACAM6 in Pan‐Gastrointestinal Cancers
Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.Expression of CEACAM6 in spatial transcriptomic of colorectal cancer with liver metastases. (A) Predicted cell types mapping on colorectal cancer tissue slice; (B) Spatial distribution of CEACAM6; (C) Spatial distribution of malignant region, mixed region and normal region; (D) The difference expression of CEACAM6 in malignant region, mixed region and ...
Liying Jin +3 more
wiley +1 more source
Construction of three strains of recombinant oncolytic vaccinia virus and their anti-tumor activity [PDF]
Jichu yixue yu linchuang, 2020 Objective The aim of this study is to construct a recombinant oncolytic vaccinia virus with CCL5 and SSTR2 genes and to detect its antitumor activity. Methods Recombinant vaccinia virus eukaryotic expression plasmid pSC65-CCL5-SSTR2-Luc+ was constructed.
LI Dan-yang, FANG Jing-jing, TANG Hui
doaj
More Than Microbiome and Medicine
Microbiota Medicine Research, EarlyView.
Faming Zhang +2 more
wiley +1 more source
Tumor Immunotherapy and Microbiome: From Bench‐to‐Bedside Applications
MedComm, Volume 7, Issue 2, February 2026.The microbiome is related to the efficacy of immunotherapy and can be utilized to predict the efficacy and adverse reactions of immunotherapy. Microbiome‐targeted intervention strategies can improve the efficacy of ICI, but necessitating more comprehensive exploration.
Anqi Lin +12 more
wiley +1 more source