Results 101 to 110 of about 22,475 (211)

Pharmacokinetics and bioavailability study of two ondansetron oral soluble film formulations in fasting healthy male Chinese volunteers

, 2015
Yubing Zhu,1 Qian Zhang,1 Jianjun Zou,2 Meng Wan,1 Zheng Zhao,1 Junrong Zhu1 1Department of Pharmacy, 2Laboratory of Clinical Pharmacology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, People’s Republic of China ...
Zhu YB, Zhu JR, Zou JJ, Wan M, Zhao Z, Zhang Q   +5 more
core  

The Comparison Effect of Preoperative Ondansetron and Metoclopramide in Reducing Nausea and Vomitting after Loparoscopic Cholecystectomy

Journal of Ardabil University of Medical Sciences, 2013
Background & Objectives: Postoperative nausea and vomiting (PONV) is one of the most common complications of anesthesia and without prophylactic intervention occurs in about one-third of patients under general anesthesia.
Masoud Entezariasl, Khatereh Isazadehfar, Zahra Noorani   +2 more
doaj  

Serotonin engages divergent 5‐HT receptor pathways for cell type‐resolved modulation of prefrontal layer 5 microcircuits

British Journal of Pharmacology, Volume 183, Issue 19, Page 5832-5853, October 2026.
Serotonin differentially modulates layer 5 mPFC microcircuits through cell type‐specific pre‐ and postsynaptic receptor pathways. Presynaptic 5‐HT1BRs suppress glutamate and GABA release, whereas presynaptic and postsynaptic 5‐HT3ARs enhance fast‐spiking interneuron activity, whilst distinct pyramidal neuron subtypes exhibit divergent 5‐HT1AR‐ and 5 ...
Ramya Rama, Guanxiao Qi, Gabriele Radnikow, Danqing Yang, Dirk Feldmeyer   +4 more
wiley   +1 more source

Systemic Inflammation and Subclinical Hepatic Synthetic Dysfunction Following Doxorubicin‐Cyclophosphamide Chemotherapy in Ethiopian Women With Breast Cancer: A Prospective Cohort Study

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims Doxorubicin‐cyclophosphamide (AC) chemotherapy induces hepatotoxicity through oxidative stress and inflammatory pathway activation, but prospective African data are lacking and conventional liver tests may miss subclinical injury.
Tamrat Nida, Abdisa Tufa Bedada
wiley   +1 more source

Fatal Cardiac Arrest in 2 Children: Possible Role of Ondansetron. [PDF]

, 2016
INTRODUCTION: Ondansetron is commonly used to treat vomiting in gastroenteritis, but has a United States Food and Drug Administration black box warning for risk of Q wave to T wave time interval (QT) prolongation.
Boucher, Jenny, PharmD, JD, BCPS, Brenner, Scott M, MD, FAAP   +1 more
core   +1 more source

Multicenter Privacy‐Preserving Federated Models for Predicting Postoperative Delirium and Acute Kidney Injury in Older Patients

MedComm, Volume 7, Issue 9, September 2026.
Using data from five medical centers, this study retrospectively evaluated a simulated federated learning framework for predicting postoperative delirium and acute kidney injury in older surgical patients. Federated learning achieved performance comparable to centralized learning without direct exchange of raw patient data.
Qian Wang, Yu‐xiang Song, Xiao‐dong Yang, Jing‐wei Zhang, Rui‐zhe Sun, Xiao‐dong Wu, Ao Li, Jing‐sheng Lou, Hao Li, Yan‐hong Liu, Jun‐mei Xu, Di‐fen Wang, Qing‐ping Wu, Yu‐ming Peng, Yi‐qiang Chen, Jiang‐bei Cao, Wei‐dong Mi   +16 more
wiley   +1 more source

Comparison of ramosetron and ondansetron for the treatment of established postoperative nausea and vomiting after laparoscopic surgery: a prospective, randomized, double-blinded multicenter trial

, 2018
Yong Seon Choi,1,* Hye-Min Sohn,2,* Sang-Hwan Do,2 Kyeong Tae Min,1 Jae Hee Woo,3 Hee Jung Baik3 1Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Severance Hospital, Yonsei University College of Medicine, Seoul ...
Woo JH, Sohn HM, Min KT, Do SH, Baik HJ, Choi YS   +5 more
core  

An Intraoperative EEG Biomarker for Postoperative Delirium Predicting Based on Interpretable Deep Learning Framework

MedComm, Volume 7, Issue 9, September 2026.
An interpretable intraoperative EEG framework predicts postoperative delirium (POD) in older surgical patients. A data‐driven best temporal filter (BTF) reveals frontal sensitivity and captures a distinctive 2–12 Hz (δ–θ–α) spindle‐like target wave occurring more frequently in POD patients, enabling event‐quantifiable intraoperative monitoring and ...
Yinuo Zhang, Yan Zhu, Xinxin Zhang, Xinke Shen, Xuemiao Tang, Zhihong Lu, Chong Lei, Mengyu Li, Hailong Dong, Zhichao Liang, Quanying Liu, Guangchao Zhao   +11 more
wiley   +1 more source

Ondansetron does not inhibit the analgesic effect of alfentanil [PDF]

, 2017
5-Hydroxytryptamine (5-HT) causes antinociception via presynaptic 5-HT3 (5-HT subtype 3) receptors on primary afferent nociceptive neurones in the spinal cord dorsal horn.
PETERSEN-FELIX, S., ARENDT-NIELSEN, L., BAK, P., BJERRING, P., SVENSSON, P., BREIVIK, H., ZBINDEN, A. M.   +6 more
core  

Prescription Medication Use During Pregnancy and Postpartum in Sweden 2007 to 2022

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Purpose Medication use during pregnancy has increased worldwide. The aim was to investigate patterns of prescription medication use during pregnancy and postpartum in Sweden 2007–2022. Methods We conducted a population‐based drug utilization study with linked data from the Swedish Medical Birth and Prescribed Drug Registers.
Essi Whaites Heinonen, Awad I. Smew, Silvia Segovia Chacón, Ulrika Nörby, Olof Stephansson, Anne K. Örtqvist, Cathrine Axfors, Pär Karlsson, Carolyn E. Cesta   +8 more
wiley   +1 more source