Ondansetron is an FDA‐approved selective serotonin 5‐HT3 receptor commonly indicated as an anti‐emetic agent for nausea and vomiting. It is rare to observe fatal reactions from ondansetron despite having no allergies or previous exposure.
Eden Firew +5 more
doaj +1 more source
The role of ondansetron in the management of cholestatic or uremic pruritis - a systematic review [PDF]
Pruritus associated with hepatic or renal failure can be a troublesome symptom, refractory to treatment, associated with significant physical and emotional distress, and reduction in quality of life for patients already burdened with chronic disease ...
Clark, Katherine +4 more
core +1 more source
Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study [PDF]
Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure change
A Freeman +47 more
core +1 more source
Elucidation of the Crystal Structures and Dehydration Behaviors of Ondansetron Salts
In drug development, it is extremely important to evaluate the solubility and stability of solid states and to immediately determine the potential for development.
Ryo Mizoguchi, Hidehiro Uekusa
doaj +1 more source
Severe acute dystonia induced by ondansetron in a paediatric patient: a case report
Ondansetron, a 5-HT3 serotonin receptor antagonist, is widely used to manage nausea and vomiting, particularly in postoperative recovery, chemotherapy, and paediatric gastroenteritis.
Kishore Nagaraju +4 more
doaj +1 more source
Magnesium sulphate in the treatment of acute asthma: evaluation of current practice in adult emergency departments [PDF]
Background: A recent meta-analysis showed that intravenous and nebulised magnesium sulphate have similar levels of evidence to support their use in the treatment of acute asthma in adults. This consisted of weak evidence of effect on respiratory function
Goodacre, S., Jones, L.A.
core +1 more source
Current radiation medical countermeasures primarily focus on hematopoietic acute radiation syndrome (H‐ARS) using agents like granulocyte colony‐stimulating factor (G‐CSF), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), and romiplostim, alongside treatments for internal contamination (Prussian blue, diethylenetriamine pentaacetate [DTPA ...
Wen‐Bing Ma +12 more
wiley +1 more source
Background The unopposed vagal activity with sympathetic block and maternal bradycardia that is likely to occur with phenylephrine infusion might be some causes of intraoperative nausea and vomiting (IONV) during spinal anaesthesia. We aimed at comparing
Mostafa Samy Abbas +4 more
doaj +1 more source
Efficacy of Three Different Prophylactic Treatments for Postoperative Nausea and Vomiting after Vitrectomy: A Randomized Clinical Trial [PDF]
Postoperative nausea and vomiting (PONV) after vitreoretinal surgery may potentially be associated with severe complications, such as suprachoroidal hemorrhage.
Astuto, M. +18 more
core +3 more sources
Pharmacokinetic profiles of sertraline in pregnancy as a predictor of postpartum depressive symptoms
Aim To characterize pharmacokinetic changes of sertraline and its metabolite during pregnancy and postpartum, and their relationship to maternal postpartum depressive symptoms. Methods This was a prospective observational, longitudinal study of pregnant women with a major depressive disorder treated with sertraline (N = 185 women, 205 pregnancies ...
Sílvia M. Illamola +8 more
wiley +1 more source

