Results 31 to 40 of about 29,325 (273)

Effects of ondansetron and [6]-gingerol on pica and gut microbiota in rats treated with cisplatin

Drug Design, Development and Therapy, 2019
Purpose [6]-gingerol is one of the main components of ginger with many biological activities. In this study, the effects of ondansetron and [6]-gingerol on pica and gut microbiota in rats injected with cisplatin were evaluated.
Xiaodi Feng, Qian-qian Cheng, Qi Meng, Yanhong Yang, K. Nie   +4 more
semanticscholar   +1 more source

A Prospective, Randomized, Double-Blinded Study of the Effect of Intravenous Ondansetron on the Effective Dose in 50% of Subjects of Prophylactic Phenylephrine Infusions for Preventing Spinal Anesthesia–Induced Hypotension During Cesarean Delivery

Anesthesia and Analgesia, 2019
BACKGROUND: Ondansetron has been shown to reduce the incidence of hypotension and vasopressor requirement during spinal anesthesia for obstetric and nonobstetric surgery. However, the magnitude of this effect has not been fully quantified.
F. Xiao, Chang-na Wei, X. Chang, Yinfa Zhang, L. Xue, Huaxiang Shen, W. N. Ngan Kee, Xin-zhong Chen   +7 more
semanticscholar   +1 more source

Intravenous Ondansetron in Pregnancy and Risk of Congenital Malformations.

Journal of the American Medical Association (JAMA), 2019
This pharmacoepidemiology study uses Medicaid data to estimate associations between first-trimester use of intravenous ondansetron and risk of cardiac malformations and oral cleft in children of exposed mothers.
K. Huybrechts, S. Hernández-Díaz, L. Straub, K. Gray, Yanmin Zhu, H. Mogun, B. Bateman   +6 more
semanticscholar   +1 more source

Ondansetron use in the first trimester of pregnancy and the risk of neonatal ventricular septal defect.

International Journal of Epidemiology, 2019
BACKGROUND Literature is divided regarding the risk of neonatal ventricular septal defect (VSD) associated with first trimester ondansetron use in pregnancy.
Lara S Lemon, L. Bodnar, W. Garrard, R. Venkataramanan, R. Platt, O. Marroquin, S. Caritis   +6 more
semanticscholar   +1 more source

Effects of ondansetron alone and in combination with domperidone in the prevention of chemotherapy-induced nausea and vomiting in breast cancer patients

Bangladesh Journal of Pharmacology, 2007
The efficacy and safety of ondansetron, administered alone and in combination with domperidone to prevent chemotherapy-induced nausea and vomiting of breast cancer patients receiving chemotherapy FAC regimen (5-fluorouracil, adriamycin and ...
Kaberi Das Gupta, A. K. M. Mosharrof Hossain, Abdur Raquib Jaigirdar, Borhan Uddin, Tridiv Choudhury, Dipti Rani Saha   +5 more
doaj   +1 more source

Phenylephrine, ondansetron, or combination of both for prevention of intraoperative nausea and vomiting in patients undergoing lower segment cesarean section: A prospective, double-blind randomized control trial

Bali Journal of Anesthesiology, 2023
Background: Intraoperative nausea and vomiting (IONV) are common complications in patients undergoing lower segment cesarean section (LSCS) under subarachnoid block.
Vikram Bedi, Pratibha Yadav, Bishan Kumar Bairwa, Santosh Choudhary, Naveen Kumar, Gayatri Deshpande   +5 more
doaj   +1 more source

Minimal effective weight-based dosing of ondansetron to reduce hypotension in cesarean section under spinal anesthesia: a randomized controlled superiority trial

BMC Anesthesiology, 2018
BackgroundThe weight-based dosing of ondansetron to reduce hypotension has never been investigated. The aim of this study is to determine the optimal dose of ondansetron required based on the patient’s weight to reduce hypotension following spinal ...
M. Oofuvong, Thitikan Kunapaisal, Orarat Karnjanawanichkul, Nussara Dilokrattanaphijit, Jaranya Leeratiwong   +4 more
semanticscholar   +1 more source

Effect of ondansetron on prevention of post-induction hypotension in elderly patients undergoing general anesthesia: A randomized, double-blind placebo-controlled clinical trial

Saudi Journal of Anaesthesia, 2015
Background: Elderly patients are susceptible to post-induction hypotension. Volume loading and vasopressors for prevention of hypotension in elderly patients may increase perioperative cardiovascular risks.
Mohammad Golparvar, Mahmoud Saghaei, Mohammad Ali Saadati, Shadi Farsaei   +3 more
doaj   +1 more source

The association between ondansetron use and mortality risk of traumatic brain injury patients: a population-based study

Frontiers in Pharmacology
Background:Traumatic brain injury (TBI) patients suffer high risks of mortality. Ondansetron has been verified to be effective in improving the prognosis of some kinds of critically ill patients. We design this study to explore whether ondansetron use is
Ruoran Wang, Jing Zhang, Jianguo Xu, Min He   +3 more
doaj   +1 more source

Hyoscine butyl-bromide versus ondansetron for nausea and vomiting during caesarean delivery under spinal anaesthesia. A randomized clinical trial

Egyptian Journal of Anaesthesia, 2023
Background The unopposed vagal activity with sympathetic block and maternal bradycardia that is likely to occur with phenylephrine infusion might be some causes of intraoperative nausea and vomiting (IONV) during spinal anaesthesia. We aimed at comparing
Mostafa Samy Abbas, Asmaa Shabaan Ahmed, Nawal Abd El-Aziz Gad El-Rab, Ahmed MA Sobh, Ahmed Aboulfotouh   +4 more
doaj   +1 more source