Results 111 to 120 of about 341,624 (160)

Associations between Circulating Biomarkers of One-Carbon Metabolism and Mitochondrial D-Loop Region Methylation Levels. [PDF]

Epigenomes
Stoccoro A, Lari M, Migliore L, Coppedè F.   +3 more
europepmc   +1 more source

Dysfunctional one-carbon metabolism identifies vitamins B₆, B₉, B₁₂, and choline as neuroprotective in glaucoma. [PDF]

Cell Rep Med
Tribble JR, Wong VHY, Stuart KV, Chidlow G, Nicol A, Rombaut A, Rabiolo A, Hoang A, Lee PY, Rutigliani C, Enz TJ, Canovai A, Lardner E, Stålhammar G, Nguyen CTO, Garway-Heath DF, Casson RJ, Khawaja AP, Bui BV, Williams PA.   +19 more
europepmc   +1 more source

The one-carbon metabolism as an underlying pathway for placental DNA methylation - a systematic review. [PDF]

Epigenetics
van Vliet MM, Schoenmakers S, Gribnau J, Steegers-Theunissen RPM.   +3 more
europepmc   +1 more source

One‐carbon metabolism and microbial pathogenicity [PDF]

Molecular Oral Microbiology, 2023
AbstractOne‐carbon metabolism (OCM) pathways are responsible for several functions, producing a number of one‐carbon unit intermediates (formyl, methylene, methenyl, methyl) that are required for the synthesis of various amino acids and other biomolecules such as purines, thymidylate, redox regulators, and, in most microbes, folate.
Kendall S. Stocke, Richard J. Lamont
openaire   +3 more sources

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One-carbon metabolism and epigenetics

Molecular Aspects of Medicine, 2017
The function of one-carbon metabolism is that of regulating the provision of methyl groups for biological methylation reactions including that of DNA and histone proteins. Methylation at specific sites into the DNA sequence and at histone tails are among the major epigenetic feature of mammalian genome for the regulation of gene expression. The enzymes
FRISO, Simonetta, Udali, Silvia, DE SANTIS, DOMENICA, Choi, Sang Woon   +3 more
openaire   +3 more sources

Nutrition, one-carbon metabolism and arsenic methylation

Toxicology, 2021
Exposure to arsenic (As) is a major public health concern globally. Inorganic As (InAs) undergoes hepatic methylation to form monomethyl (MMAs)- and dimethyl (DMAs)-arsenical species, facilitating urinary As elimination. MMAsIII is considerably more toxic than either InAsIII or DMAsV, and a higher proportion of MMAs in urine has been associated with ...
Ahlam Abuawad, Anne K. Bozack, Roheeni Saxena, Mary V. Gamble   +3 more
openaire   +2 more sources

One-carbon metabolism and bipolar disorder

Australian & New Zealand Journal of Psychiatry, 2013
Objective: Folate is one of the most widely used nutraceuticals for the treatment of mood disorders. In this article, we review folate metabolism, its relationship with bipolar disorder, and its therapeutic potential. Methods: We searched PubMed and the Cochrane Library for relevant articles up to and including the year 2012.
Ji Hyun, Baek, Emily E, Bernstein, Andrew A, Nierenberg   +2 more
openaire   +2 more sources

Gene-Nutrient Interactions in One-Carbon Metabolism

Current Drug Metabolism, 2005
Advances in molecular biology greatly contributed, in the past decades, to a deeper understanding of the role of gene function in disease development. Environmental as well as nutritional factors are now well acknowledged to interact with the individual genetic background for the development of several diseases, including cancer, cardiovascular disease,
FRISO, Simonetta, S.W. Choi
openaire   +3 more sources

One-Carbon Metabolism and Lipid Metabolism in DOHaD

2018
The predisposing factors to lifestyle-associated diseases are established in the early period of life with underlying gene-environment interaction. Epigenetics is a chemical modification-based genetic mechanism that is affected by various nutritional factors.
Hideoki, Fukuoka, Takeo, Kubota
openaire   +2 more sources