Results 41 to 50 of about 248,702 (267)

Trees from Functions as Processes [PDF]

open access: yes, 2018
Levy-Longo Trees and Bohm Trees are the best known tree structures on the {\lambda}-calculus. We give general conditions under which an encoding of the {\lambda}-calculus into the {\pi}-calculus is sound and complete with respect to such trees.
Sangiorgi, Davide, Xu, Xian
core   +4 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Lazy Evaluation and Delimited Control [PDF]

open access: yes, 2010
The call-by-need lambda calculus provides an equational framework for reasoning syntactically about lazy evaluation. This paper examines its operational characteristics.
Amr Sabry   +7 more
core   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

No value restriction is needed for algebraic effects and handlers

open access: yes, 2016
We present a straightforward, sound Hindley-Milner polymorphic type system for algebraic effects and handlers in a call-by-value calculus, which allows type variable generalisation of arbitrary computations, not just values. This result is surprising. On
Kammar, Ohad, Pretnar, Matija
core   +1 more source

First Class Call Stacks: Exploring Head Reduction [PDF]

open access: yes, 2016
Weak-head normalization is inconsistent with functional extensionality in the call-by-name $\lambda$-calculus. We explore this problem from a new angle via the conflict between extensionality and effects.
Ariola, Zena M.   +2 more
core   +2 more sources

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Ellipses and Lambda Definability [PDF]

open access: yesLogical Methods in Computer Science, 2015
Ellipses are a meta-linguistic notation for denoting terms the size of which are specified by a meta-variable that ranges over the natural numbers. In this work, we present a systematic approach for encoding such meta-expressions in the \^I-calculus ...
Mayer Goldberg
doaj   +1 more source

NRASQ61R Expression in Lymphatic Endothelial Cells Causes Enlarged Vessels, Hemorrhagic Chylous Effusions, and High Mortality in a Mouse Model of Kaposiform Lymphangiomatosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel   +3 more
wiley   +1 more source

Financial Burden Associated With Hospitalisation Among Families of Childhood Brain Tumours in Australia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy