Results 51 to 60 of about 18,592,973 (299)

Energy-Optimal Trajectory Planning for Planar Underactuated RR Robot Manipulators in the Absence of Gravity

open access: yesAbstract and Applied Analysis, 2013
In this paper, we study the trajectory planning problem for planar underactuated robot manipulators with two revolute joints in the absence of gravity.
John Gregory   +2 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito   +7 more
wiley   +1 more source

Automatic Probabilistic Program Verification through Random Variable Abstraction [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2010
The weakest pre-expectation calculus has been proved to be a mature theory to analyze quantitative properties of probabilistic and nondeterministic programs.
Damián Barsotti, Nicolás Wolovick
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Map Calculus in GIS: a proposal and demonstration [PDF]

open access: yes, 2004
This paper provides a new representation for fields (continuous surfaces) in Geographical Information Systems (GIS), based on the notion of spatial functions and their combinations.
Haklay, M
core  

Comportement des poteaux mixtes acier-béton soumis aux sollicitations de type monotone. Étude expérimentale [PDF]

open access: yesBulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2006
For more than one hundred years the construction system based on steel or composite steel -- concrete frames became one of the more utilized types of building in civil engineering domain. For an optimal dimensioning of the structure, the engineers had to
Cristina Câmpian
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Was the Early Calculus an Inconsistent Theory? [PDF]

open access: yes, 2007
The ubiquitous assertion that the early calculus of Newton and Leibniz was an inconsistent theory is examined. Two different objects of a possible inconsistency claim are distinguished: (i) the calculus as an algorithm; (ii) proposed explanations of the ...
Vickers, Peter
core  

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