Results 51 to 60 of about 18,592,973 (299)
In this paper, we study the trajectory planning problem for planar underactuated robot manipulators with two revolute joints in the absence of gravity.
John Gregory +2 more
doaj +1 more source
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa +7 more
wiley +1 more source
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Automatic Probabilistic Program Verification through Random Variable Abstraction [PDF]
The weakest pre-expectation calculus has been proved to be a mature theory to analyze quantitative properties of probabilistic and nondeterministic programs.
Damián Barsotti, Nicolás Wolovick
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Map Calculus in GIS: a proposal and demonstration [PDF]
This paper provides a new representation for fields (continuous surfaces) in Geographical Information Systems (GIS), based on the notion of spatial functions and their combinations.
Haklay, M
core
Comportement des poteaux mixtes acier-béton soumis aux sollicitations de type monotone. Étude expérimentale [PDF]
For more than one hundred years the construction system based on steel or composite steel -- concrete frames became one of the more utilized types of building in civil engineering domain. For an optimal dimensioning of the structure, the engineers had to
Cristina Câmpian
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Was the Early Calculus an Inconsistent Theory? [PDF]
The ubiquitous assertion that the early calculus of Newton and Leibniz was an inconsistent theory is examined. Two different objects of a possible inconsistency claim are distinguished: (i) the calculus as an algorithm; (ii) proposed explanations of the ...
Vickers, Peter
core

