Results 61 to 70 of about 23,979 (264)

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala, Riitta Niinimäki, Tytti Pokka, Anu Huurre, Liisa Järvelä, Sauli Palmu, Tuuli Pöyhönen, Pauliina Utriainen, Henri Aarnivala   +8 more
wiley   +1 more source

APPLICATION OF INFORMATION FUNCTIONS FOR THE ANALYSIS AND EFFECTIVENESS INCREASE OF THE TESTS IN HIGHER MATHEMATICS

Інформаційні технології і засоби навчання, 2014
The present paper studies the issue of effectiveness analysis of pedagogical tests based on calculation of information functions. The algorithms of computation and analysis of information function depending on the type of test item and the chosen model ...
Oleksandr A. Dykhovychnyi, Anna F. Dudko
doaj  

One-variable and multi-mariable calculus on a non-Archimedean field extension of the real numbers [PDF]

P-Adic Numbers, Ultrametric Analysis, and Applications, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +1 more source

Administering Blinatumomab via Continuous Intravenous Infusion in Pediatric Patients—A Single‐Institution Retrospective Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Blinatumomab, a CD19xCD3 bispecific T‐cell engager, has become standard therapy for children with de novo B‐cell acute lymphoblastic leukemia (B‐ALL). This retrospective review describes the experience of blinatumomab administration in pediatric patients.
Julia M. Hurley, Ryleigh Krueger, Kellie Joyce, James Stanley, Mary Waskerwitz‐Freyer, Marielle Klunder, David J. Hoogstra   +6 more
wiley   +1 more source

Simulation and motion study of mechanical integrator 3D model [PDF]

FME Transactions, 2019
A Mechanical Integrator is a mechanical device which can be used to obtain the continual integration of the input variable value. This paper explains the operational principles and discloses the simulation and motion study results of the mechanical ...
Popkonstantinovic Branislav, Stojicevic Misa, Jeli Zorana, Obradovic Milos, Dragos-Laurentiu Popa   +4 more
doaj  

Increasing Interpersonal Interactions in an Online Course: Does Increased Instructor E-mail Activity and a Voluntary In-Person Meeting Time Facilitate Student Learning?

Online Learning, 2018
Distance learning is expanding rapidly in universities. While theoretical and qualitative literature stress the critical role of effective interpersonal interactions in motivating students and facilitating learning in online environments, quantitative ...
Bianca Cung, Di Xu, Sarah Eichhorn
doaj   +1 more source

Occurrence of Extramedullary Relapses in Pediatric Acute Lymphoblastic Leukemia After Treatment With Blinatumomab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz, Martin Ebinger, Michaela Döring, Markus Mezger, Ursula Holzer, Rupert Handgretinger, Peter Lang, Manon Queudeville   +7 more
wiley   +1 more source

Fractional and Integrable Perspectives on a Variable-Coefficient Semi-Discrete NLS Equation: Analytical Method and Engineering Applications

Fractal and Fractional
The method of deriving fractional-order differential equations using Riesz fractional-order calculus is a new breakthrough, and it is possible to use the inverse scattering transform (IST) to solve the analytical solutions of the derived equations ...
Sen Zhao, Sheng Zhang, Bo Xu
doaj   +1 more source

Prediction of Basic Math Course Failure Rate in the Physics, Meteorology, Mathematics, Actuarial Sciences and Pharmacy Degree Programs

Revista Electrónica Educare, 2014
This paper summarizes a study conducted in 2013 with the purpose of predicting the failure rate of math courses taken by Pharmacy, Mathematics, Actuarial Science, Physics and Meteorology students at Universidad de Costa Rica (UCR).
Luis Rojas-Torres
doaj   +1 more source