Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
LncRNA DANCR Activates p38/mTOR-Mediated Autophagy via ANXA2 to Exacerbate Oxygen-Induced Retinal Neovascularization in Mice. [PDF]
Wang Y, Bai J, Zhao S.
europepmc +1 more source
Alzheimer's disease-linked ACE variants increase ACE1 catalytic activity and production of angiotensin II. [PDF]
Salvo MA +5 more
europepmc +1 more source
Effects of Extremely Low Frequency Magnetic Field Exposure (50 Hz, 200 µT) on Cell Viability, DNA Damage and Micronucleus Formation of Human Skin Cells. [PDF]
Meyer V, Drees K, Gronau IA, Lerchl A.
europepmc +1 more source
Global temperature anomaly prediction by using additive twin LSTM networks. [PDF]
Keles C, Baran B, Alagoz BB.
europepmc +1 more source
Sorting nexin 10 knockdown: new strategies for alleviating sepsis-associated acute lung injury. [PDF]
Wei M +8 more
europepmc +1 more source
Kaempferol alleviates T-cell immunosenescence and inflammaging in aged mice via the SIRT3-LKB1-AMPK-mitophagy pathway. [PDF]
Chen W +10 more
europepmc +1 more source

