Results 101 to 110 of about 7,506,157 (312)
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Summary: Background: Childhood vaccinations can reduce disease burden and associated antibiotic use, in turn reducing the risk of antimicrobial resistance (AMR).
Chirag K. Kumar +6 more
doaj +1 more source
One Health and Neglected Tropical Diseases—Multisectoral Solutions to Endemic Challenges
One Health is defined as an approach to achieve better health outcomes for humans, animals, and the environment through collaborative and interdisciplinary efforts.
Claire J. Standley +5 more
core +1 more source
One Health challenges for pig reproduction
The current state of the world challenges pig reproduction as an important part of One Health, which involves interrelationships between animal, human and environmental health.
Maria Kareskoski +5 more
core +1 more source
'One toxicology', 'ecosystem health' and 'one health'.
'One Health' as a discipline links human and veterinary medicine as co-equal partners in an increasingly efficient joint venture into health promotion and prioritised research. 'One Toxicology' is proposed as a way to reunify toxicology as a component of 'Ecosystem Health' and the encompassing 'One Health'.
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
The non-traditional challenges of conducting science in developing countries: the case of Ecuador
Scientific progress has been predominantly driven by countries in the Global North, which benefit from robust infrastructure, greater funding, and supportive research policies.
Esteban Ortiz-Prado +3 more
doaj +1 more source
Candida albicans (C. albicans), a common pathogenic fungus in nature, has enough capacity to cause severe brain infection through various means under immunocompromised conditions.
Mingsheng Li +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source

