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Workshop summary : One Health Zoonotic Disease Prioritization for Multi-Sectoral Engagement in Burkina Faso, Ouagadougou, Burkina Faso [PDF]

Zoonotic diseases are diseases capable of spreading between animals and humans. Most known human infectious diseases and about three-quarters of newly emerging infections originate from animals.

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Telatar, B. Editör Yazısı : Editör Yazısı

, 2023
Sevgili okurlarımız,Tek sağlık kavramı farklı disiplinlerin sağlığı korunması ve geliştirilmesi için bir araya gelmesini, ortak bir çatı altında çalışmasını hedefleyen bir kavramdır. Tek sağlık fikrinin Karl Virchow tarafından ilk defa ortaya atılmasının

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From 'two medicines' to 'One Health' and beyond [PDF]

, 2012
We first review historic and conceptual background to integrative thinking in medicine. Lacking a general theory of ‘One Health’, we provide an operational definition of ‘One Health’ and its leverage as: any added value in terms of human and animal ...
Marcel Tanner, Meisser, A., Bassirou Bonfoh, Schelling, E., Tanner, M., Esther Schelling, Andrea Meisser, Jakob Zinsstag, Zinsstag, J., Bonfoh, B.   +9 more
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Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Navigating One Health in research-for-development: Reflections on the design and implementation of the CGIAR Initiative on One Health

Adopting One Health approaches is key for addressing interconnected health challenges. Yet, how to best put One Health into practice in research-for-development initiatives aiming to ‘deliver impacts’ remains unclear.
Lam, Steven; Hoffmann, Vivian; Bett, Bernard; Fèvre, Eric M.; Moodley, Arshnee; Mohan, Chadag V.; Mateo-Sagasta, Javier; Hung Nguyen-Viet
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The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Uppsala Health Summit Post-conference Briefs 2023 : Chemical Pollution and One Health - from Reactivity to Proactivity

, 2023
Please refer to individual briefs:Towards an intergovernmental panel on pollution and toxic wasteTesting our way to a safe environmentHealth and environmental challenges of recycling chemicals in a sustainable management of plasticsFuture monitoring of ...

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Evaluation of the reinforced integrated disease surveillance and response strategy using short message service data transmission in two southern regions of Madagascar, 2014–15

BMC Health Services Research, 2018
Background The Integrated Disease Surveillance and Response (IDSR) strategy was introduced in Madagascar in 2007. Information was collected by Healthcare structures (HS) on paper forms and transferred to the central level by post or email.
Rado Randriamiarana, Grégoire Raminosoa, Nikaria Vonjitsara, Rivo Randrianasolo, Harena Rasamoelina, Harimahefa Razafimandimby, Arthur Lamina Rakotonjanabelo, Richard Lepec, Loïc Flachet, Ariane Halm   +9 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

One Health Zoonotic Disease Prioritization Process [PDF]

The One Health Zoonotic Disease Prioritization (OHZDP) process brings together representatives from human, animal, and environmental health sectors, as well as other relevant partners, to prioritize zoonotic diseases of greatest concern for multisectoral,

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