Results 131 to 140 of about 7,692,761 (259)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Antagonistic activity of Bacillus velezensis L09 isolated from crocodile gut against Aeromonas dhakensis: Mechanisms and potential for aquaculture applications

Water Biology and Security
The global aquaculture industry is facing increasing threats from multidrug-resistant pathogens, particularly Aeromonas dhakensis, which causes septicemia in crocodiles, causes severe infections in aquatic species, and poses zoonotic risks to humans.
Boxue Zhang, Shuai Ye, Xiaoyucheng Duan, Haibo Gao, Yukun Wu, Danna Chen, Jiahao Yu, Xueqian Wang, Wei Feng, Guiying Guo, Lixia Fan, Nuo Yang, Qian Li, Xuesong Li, Jiping Zheng   +14 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Stage-Specific Effects of Silver Nanoparticles on Physiology During the Early Growth Stages of Rice

Plants
Silver nanoparticles (AgNPs), widely utilized nanomaterials, can negatively affect crop growth and development. However, it remains unclear whether crops exhibit similar responses to AgNPs stress at seed germination and seedling stages.
Ruxue Pan, Zailin Zhang, Ya Li, Sihong Zhu, Sumera Anwar, Jiaquan Huang, Chuanling Zhang, Liyan Yin   +7 more
doaj   +1 more source

Mental Health: Focusing On Health Professionals [PDF]

Revista Brasileira de Enfermagem, 2020
Elizabeth Esperidião, Maria Giovana Borges Saidel, Jeferson Rodrigues   +2 more
openaire   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Assessing One Health integration in Somalia’s school curriculum for future pandemic preparedness

CABI One Health
Background: The COVID-19 pandemic has highlighted the need for a holistic health approach, emphasizing the interconnectedness of human, animal, plant, and environmental health.
Ahmed Abdulkadir Hassan-Kadle, Aamir Muse Osman, Abas Mohamed Sharif   +2 more
doaj   +1 more source

Evaluation of the Specialist Community Public Health Nursing Peripatetic Assessment Model [PDF]

, 2017
The Health Visitor Implementation Plan 2011-15: a call to action, called for an additional 4200 health visitors to be trained by 2015. To accommodate larger numbers of students, specialist community public health nursing (SCPHN) programmes across the UK ...
Brook, J., Deave, T., Novak, C., Salmon, D.   +3 more
core   +1 more source