Results 131 to 140 of about 141,145 (298)
The Role Of Online Deliberation On Citizens' Attitudes
, 2015 In this paper, an experiment was conducted to assess the impact of online deliberation on citizens' attitudes. Specifically, this research compared pre and post deliberation opinions of participants who deliberated online via an asynchronous platform regarding the issue of political opinion polls.
Triantafillidou, Amalia +3 more
openaire +1 more source
A co-original approach towards law-making in the internet age [PDF]
, 2012 There is an increasing interest in incorporating significant citizen participation into the law-making process by developing the use of the internet in the public sphere. However, no well-accepted e-participation model has prevailed.
Chen, Chi Shing
core
PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC
Advanced Science, EarlyView.CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao +16 more
wiley +1 more source
Advanced Science, EarlyView.NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang +8 more
wiley +1 more source
Collective Intelligence Analytics Dashboard Usability Evaluation [PDF]
, 2014 Online deliberations can reach a size where it is not possible anymore to quickly infer what is going on in a debate. This report presents results from the usefulness and usability evaluation of visualisations that aid the sense ...
Bachler, Michelle +2 more
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Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Reflections from Participants [PDF]
, 2009 The Road Ahead: Public Dialogue on Science and Technology brings together some of the UK’s leading thinkers and practitioners in science and society to ask where we have got to, how we have got here, why we are doing what we are doing and what we should ...
, Sciencewise +2 more
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Advanced Science, EarlyView.Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source
Humanities & Social Sciences CommunicationsDoes the internet facilitate everyday public deliberation? Previous research on this question has largely focused on specific aspects, such as online news media diets or political discussions on social media.
Lisa Oswald
doaj +1 more source
Value-Sensitive Disagreement Analysis for Online Deliberation
Disagreements are common in online societal deliberation and may be crucial for effective collaboration, for instance in helping users understand opposing viewpoints. Although there exist automated methods for recognizing disagreement, a deeper understanding of factors that influence disagreement is currently missing.
Van Der Meer, Michiel +3 more
openaire +1 more source