Results 141 to 150 of about 8,639,294 (253)

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

From evidence to action: expert perspectives on stakeholder dialogues in Swiss health policy. [PDF]

Int J Public Health
Rubinelli S, Mesa-Vieira C, Peytremann-Bridevaux I, Diviani N, Mantwill S, Messerli NG, Fiordelli M.   +6 more
europepmc   +1 more source

Finding a Seat for Social Justice at the Table of Dialogue and Deliberation

, 2014
What does it mean for the dialogue and deliberation or public engagement community to exclude social justice from its mission and activities? Many dialogue and deliberation organizations, though clearly not all, shy away from either an explicit or ...
Schoem, David
core  

Osseoperceptive EMG Feedback Improves Grasp Force Control in Myoelectric Prosthetic Hands

Advanced Science, EarlyView.
Osseoperception is explored as a non‐invasive pathway for delivering sensory feedback in myoelectric prosthetic control. By encoding the user's electromyographic (EMG) signal through bone‐conducted stimulation, this approach enables predictive grasp force regulation.
Cristian Felipe Blanco‐Diaz, Strahinja Dosen, Leonardo Cappello   +2 more
wiley   +1 more source

Examining Discursive Features in Crowdsourced Deliberation: Idea Generation through Elaboration. [PDF]

Comput Support Coop Work
Aitamurto T, Royal P, Saldivar J.
europepmc   +1 more source

Beyond Deliberation: A Strategy for Civic Renewal

, 2014
To expand opportunities for discussion and reflection about public issues, we should look beyond the organizations that intentionally convene deliberations and also enlist organizations that preserve common resources, volunteer service groups, civics ...
Levine, Peter
core  

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

MXene‐Based Room‐Temperature NO2 Gas Sensors: A Meta‐Analysis

Advanced Science, EarlyView.
This study presents the first comprehensive meta‐analysis of MXene‐based NO2 sensors, decoding 32 study characteristics across 61 peer‐reviewed studies. By isolating materials chemistry as the primary performance driver over device‐level parameters, the authors establish a methodological blueprint and a predictive structure–function map to accelerate ...
Alexander Khort, Jerome Geyer‐Klingeberg, Andreas Rathgeber, Suelen Barg   +3 more
wiley   +1 more source

Development and pilot validation of a European ethical framework for decision-making in dementia care. [PDF]

BMC Med Ethics
Schou-Juul F, Gordijn B, Morais A, Fonseca M, Scerri A, Hinrichsen C, Porteri C, Sperling D, Kelly D, Bobrowicz-Campos E, Dogru-Huzmeli E, Jarašiūnaitė-Fedosejeva G, Thygesen H, Stončikaitė I, Alexandre IM, Rymaszewska J, Irving K, Zajdó K, Johansson L, Ferm LT, Riklikiene O, McQuillan R, Serrat R, Silva R, Schicktanz S, Bielsten T, Ulman YI, Lauridsen S.   +27 more
europepmc   +1 more source

Identifying Deliberation in Social Movement Assemblies: Challenges of Comparative Participant Observation

, 2008
Contemporary social movements can serve as a critical case for the empirical study of deliberation. In countless face-to-face meetings activists often discuss long hours before a decision is reached.
Haug, Christoph, Teune, Simon
core