Results 151 to 160 of about 8,772,756 (307)
Background and Purpose Modifying the brain–gut–microbiota axis has emerged as a promising therapeutic strategy against Alzheimer's disease (AD). Whether rifaximin, a non‐absorbed and non‐systemic antibiotic, can be applied to the treatment of AD remains unexplored.
Di Wu +7 more
wiley +1 more source
EPHX2 Loss Promotes CRC Migration via EET‐Dependent Chemokine Elevation and Mitochondrial Defect
Loss of EPHX2 promotes EET accumulation, which in turn enhances CXCL and ROS production, thereby promoting the migratory and invasive abilities of CRC cells. ABSTRACT Epoxide hydrolase 2 (EPHX2) is a key enzyme in fatty acid metabolism that metabolizes epoxyeicosatrienoic acids (EETs), lipid mediators involved in inflammation, angiogenesis, and ...
Jianjun Zhu +10 more
wiley +1 more source
Harmonization and integration of pharmacogenomics screens. [PDF]
Chen AT, Kelly MR, Ideker T, Mattson NM.
europepmc +1 more source
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou +8 more
wiley +1 more source
Exploring the treatment of liver cancer with Gehua Hugan Gao based on bioinformatics, network pharmacology, and molecular docking. [PDF]
Ye G +9 more
europepmc +1 more source
From Simplicity to the Filioque: A Proposal
Abstract I will defend the position that trinitarian metaphysics relying on a strict theory of divine simplicity has a significant ecumenical advantage over other approaches to trinitarian theology. Specifically, it can help us resolve disputes around the filioque irenically.
James Dominic Rooney
wiley +1 more source

