Results 151 to 160 of about 8,772,756 (307)

Rifaximin ameliorates memory impairment and Alzheimer's pathological changes in APP/PS1 mice associated with changes in the gut microbiome–bile acids–serum metabolites networks

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Modifying the brain–gut–microbiota axis has emerged as a promising therapeutic strategy against Alzheimer's disease (AD). Whether rifaximin, a non‐absorbed and non‐systemic antibiotic, can be applied to the treatment of AD remains unexplored.
Di Wu   +7 more
wiley   +1 more source

Britannica Concise Encyclopedia

open access: yes, 2006
The Encyclopedia Britannica
core  

EPHX2 Loss Promotes CRC Migration via EET‐Dependent Chemokine Elevation and Mitochondrial Defect

open access: yesCancer Science, EarlyView.
Loss of EPHX2 promotes EET accumulation, which in turn enhances CXCL and ROS production, thereby promoting the migratory and invasive abilities of CRC cells. ABSTRACT Epoxide hydrolase 2 (EPHX2) is a key enzyme in fatty acid metabolism that metabolizes epoxyeicosatrienoic acids (EETs), lipid mediators involved in inflammation, angiogenesis, and ...
Jianjun Zhu   +10 more
wiley   +1 more source

The New Encyclopedia Britannica [18]

open access: yes, 1995
Encyclopedia Britannica, Inc
core  

Harmonization and integration of pharmacogenomics screens. [PDF]

open access: yesBioinformatics
Chen AT, Kelly MR, Ideker T, Mattson NM.
europepmc   +1 more source

Methyl 4‐O‐Demethylbarbatate Destabilises HIF‐1α and Enhances Temozolomide Sensitivity in Glioma Cells

open access: yesCell Proliferation, EarlyView.
The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou   +8 more
wiley   +1 more source

The New Encyclopedia Britannica [27]

open access: yes, 1995
Encyclopedia Britannica, Inc
core  

From Simplicity to the Filioque: A Proposal

open access: yesInternational Journal of Systematic Theology, EarlyView.
Abstract I will defend the position that trinitarian metaphysics relying on a strict theory of divine simplicity has a significant ecumenical advantage over other approaches to trinitarian theology. Specifically, it can help us resolve disputes around the filioque irenically.
James Dominic Rooney
wiley   +1 more source

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