Results 71 to 80 of about 2,261,834 (297)

Identification of novel genes regulating the development of the palate

Developmental Dynamics, EarlyView.
Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley   +1 more source

Comparing Transcriptomic Responses to Chemicals Across Six Species Using the EcoToxChip RNASeq Database

Environmental Toxicology and Chemistry, EarlyView.
Abstract The EcoToxChip project includes RNA‐sequencing data from experiments involving model (Japanese quail, fathead minnow, African clawed frog) and ecological (double‐crested cormorant, rainbow trout, northern leopard frog) species at multiple life stages (whole embryo and adult) exposed to eight chemicals of environmental concern known to perturb ...
Krittika Mittal, Jessica Ewald, Doug Crump, Jessica Head, Markus Hecker, Natacha Hogan, Jianguo Xia, Niladri Basu   +7 more
wiley   +1 more source

A Novel Large-scale Chinese Encyclopedia Knowledge Parallel Refining Method Based on MapReduce

IEEE Access, 2019
The open collaborative characteristics of online encyclopedia and the large number of ambiguity phenomena in the encyclopedia entry lead to inappropriate classification of plenty of Infobox knowledge triples of entries, which requires for refining and ...
Ting Wang, Jie Li, Jiale Guo, Jingyao Xie   +3 more
doaj   +1 more source

China’s Digital Nationalism: Search Engines and Online Encyclopedias

The Journal of Communication and Media Studies, 2020
Search engines play a vital role in positioning, organizing, and disseminating knowledge in China. Although there is a growing interest in China’s search engines, relatively few researches systematically examine their role involving nationalism. In order to address the research gap, this article compares the top thirty search results,from Baidu, 360 ...
openaire   +4 more sources

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

The Structure of Informal Learning in the Workplace—An Experience Sampling Approach

Human Resource Development Quarterly, EarlyView.
ABSTRACT This paper complements retrospective approaches to researching informal learning in the workplace with experience sampling. Since (conscious) informal learning is becoming increasingly important for successfully keeping pace with rapid changes in working environments, a clear understanding of the construct and its precise measurement are ...
Katja Häußermann, Tina Seufert
wiley   +1 more source

Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification

International Journal of Cancer, EarlyView.
What's New? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez, Carla Debernardi, Alessandra Allione, Elton Jalis Herman, Simonetta Guarrera, Daniela Ferrante, Anna Aspesi, Marika Sculco, Marta La Vecchia, Carlotta Sacerdote, Federica Grosso, Christina M. Lill, Giovanna Masala, Marcela Guevara, Matthias B. Schulze, Salvatore Panico, Yaszan Asgari, Seehyun Park, Giovanna Tagliabue, Anne Tjønneland, Antonio Agudo, Elisabete Weiderpass, Corrado Magnani, Irma Dianzani, Paolo Vineis, Elisabetta Casalone, Giuseppe Matullo   +26 more
wiley   +1 more source

Ginseng polysaccharides prevent mastitis through Lactobacillus murinus‐derived deoxycholic acid and TGR5 signaling

iMetaOmics, EarlyView.
Prebiotic Ginseng polysaccharides (GP) alleviate mastitis through selective enrichment of gut L. murinus, which elevates its anti‐inflammatory metabolite deoxycholic acid (DCA). Circulating DCA engages mammary epithelial TGR5 receptors, triggering the cAMP–PKA pathway to suppress NF‐κB/NLRP3‐mediated inflammation.
Zhijie Zheng, Huiying Liu, Sizhe Chen, Jianhui Gu, Sisi Cai, Xiang Liu, Raphaela I. Lau, Yao Zhang, Sunjae Lee, Xiaoyan Wang, Kewei Fan, Xiaole Yin, Hein Min Tun, Renyou Gan, Haichong Wu, Qi Su   +15 more
wiley   +1 more source