Results 31 to 40 of about 19,421 (294)
Advanced Science, EarlyView.The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang +7 more
wiley +1 more source
Advanced Science, EarlyView.We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun +5 more
wiley +1 more source
Studia Lexicographica, 2023 Electronic lexicography is a branch of lexicography that deals with theoretical and practical aspects of online dictionaries, additionally encompassing encyclopedias, lexicons, glossaries, terminological repositories, and other online information tools ...
Ivana Filipović Petrović +1 more
doaj +1 more source
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
Advanced Science, EarlyView.ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu +12 more
wiley +1 more source
The Internet as a space of knowledge: psychological aspects of hypertext structures [PDF]
Современная зарубежная психология, 2017 In modern researches which could be attributed to psychology of Internet or, put another way, to cyberpsychology, works on game and communicative behavior are massively presented.
Voiskounsky A.E.
doaj +1 more source
The Human Capital “Impact” on E-Business: The Case of Encyclopedia Britannica [PDF]
, 2000 [Excerpt] The term “New Economy” has been coined to describe the remarkable economic performance of the 1990s. Stiroh, (1999) an economist at the Federal Reserve Bank of New York observes that its defining characteristic is a “focus on increasing ...
Boudreau, John W. +2 more
core +1 more source
Advanced Science, EarlyView.This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang +16 more
wiley +1 more source
Ukrainian Electronic Encyclopedias
Studia Lexicographica, 2018 This article describes contemporary Ukrainian electronic encyclopedias, proposes their general review and characterizes their main types and the thematic and typological peculiarities of both online encyclopedic products and electronic versions of ...
Yaroslav Pylynskyi
doaj
First Women, Second Sex: Gender Bias in Wikipedia
, 2015 Contributing to history has never been as easy as it is today. Anyone with access to the Web is able to play a part on Wikipedia, an open and free encyclopedia.
Graells-Garrido, Eduardo +2 more
core +1 more source