Results 31 to 40 of about 1,962 (248)

Encyclopedia of Modern Ukraine vs. Wikipedia: the popularity scale in information space of Ukraine

open access: yesЕнциклопедичний Вісник України, 2019
The article deals with the problems of the popularity of online encyclopedias in the nowadays information space. It is shown that the most popular in Ukraine is Wikipedia, and the academic Encyclopedia of Modern Ukraine is much inferior to it in this ...
Oleksandr Ishchenko
doaj   +1 more source

Genetic predisposition to porto‐sinusoidal vascular disorder: A functional genomic‐based, multigenerational family study

open access: yesHepatology, EarlyView., 2022
A deleterious variant of FCHSD1 results in mTOR pathway overactivation and may cause porto‐sinusoidal vascular disorder (PSVD). The pedigree of the family demonstrated an autosomal dominant disease with variable expressivity. Whole‐genome sequencing and Sanger sequencing both validated the existence of the FCHSD1 variant and the heterozygosity of c ...
Jingxuan Shan   +19 more
wiley   +1 more source

Ecology of the digital world of Wikipedia

open access: yesScientific Reports, 2021
Wikipedia, a paradigmatic example of online knowledge space is organized in a collaborative, bottom-up way with voluntary contributions, yet it maintains a level of reliability comparable to that of traditional encyclopedias.
Fumiko Ogushi   +3 more
doaj   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

PAGES FROM NAGYVÁRAD CITY’S FOOTBALL HISTORY (1901 – 1919)

open access: yesStudia Universitatis Babeş-Bolyai: Educatio Artis Gymnasticae, 2022
In the first part, the paper refers to the events which led to the establishment of the first sports associations of Nagyvárad city, followed by the presentation of the school sports associations and clubs that had football departments, the football ...
Norbert Csaba LUKÁCS
doaj   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Integration of Spatiotemporal Multi‐Omics in Peach Fruit Unravels a Metabolic Niche and the Genetic Basis of Trichome‐Mediated Stress Adaptation

open access: yesAdvanced Science, EarlyView.
This study constructed the first spatiotemporal multi‐omics map of peach fruit and discovered a key candidate gene that synergistically regulates trichome development and drought tolerance through the jasmonic acid signaling pathway, providing insights into the coupling mechanism between development and stress resistance.
Zhixin Liu   +9 more
wiley   +1 more source

Electronic dictionaries in the information age: Examples of solutions in dictionaries of Croatian and other languages

open access: yesStudia Lexicographica, 2023
Electronic lexicography is a branch of lexicography that deals with theoretical and practical aspects of online dictionaries, additionally encompassing encyclopedias, lexicons, glossaries, terminological repositories, and other online information tools ...
Ivana Filipović Petrović   +1 more
doaj   +1 more source

Open Source Software for Open Access Encyclopedias [PDF]

open access: yes, 2017
The main objective of the project “Open Encyclopedia System (OES)” is to develop a standardized web-based open source platform for building and maintaining scientific online encyclopedias, which will be publicly available, free of charge on the ...
Egilmez, Ilker   +2 more
core   +1 more source

Pharmacologic Modulation of ARID3A with Rimegepant Reactivates Type I Interferon Signaling and Sensitizes Triple‐Negative Breast Cancer to PD‐1 Blockade

open access: yesAdvanced Science, EarlyView.
This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou   +12 more
wiley   +1 more source

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