Results 51 to 60 of about 1,962 (248)

On the digital republishing of Ukrainian literary classics [PDF]

open access: yesЕнциклопедичний Вісник України
This communication examines the creation and implementation of a series of interconnected online encyclopedias dedicated to the works of prominent Ukrainian figures: Taras Shevchenko, Ivan Franko, Mykhailo Hrushevsky, and Lesia ...
Vladyslav Mukha
doaj   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin   +11 more
wiley   +1 more source

Lexicon of Media Terms as an Attempt to Synthesize the Knowledge about the Mediasphere of the 21st Century from the Polish Perspective

open access: yesZeszyty Prasoznawcze, 2022
The article presents the idea of a new “Lexicon of Media Terms” in Poland, showing important reasons for undertaking such a project.
Kazimierz Wolny-Zmorzyński   +2 more
doaj   +1 more source

The practice of developing web-oriented encyclopedias in Ukraine [PDF]

open access: yes, 2023
Мета дослідження полягає у визначенні кращих вітчизняних практик розроблення веборієнтованих енциклопедій на основі аналізу функціональних особливостей та їх програмної реалізації.
Лупаренко, Л. А.   +1 more
core  

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

open access: yesAdvanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu   +11 more
wiley   +1 more source

Fiction et forme encyclopédique : Wookieepedia, Dragon Ball Wiki et Cie.

open access: yesStrenae, 2011
Wookieepedia, Final Fantasy Wiki, Dragon Ball Wiki, Memory Alpha, WoWWiki... So many online encyclopedias deal with famous young adult and children’s fiction, through an often vast number of articles, tackling all sorts of subjects (stories, technologies,
Benoît Berthou
doaj   +1 more source

Cannabis for pain: a cross-sectional survey of the patient information quality on the Internet

open access: yesJournal of Cannabis Research, 2021
Background Cannabis has increasingly become an alternative treatment for chronic pain, however, there is evidence of concomitant negative health effects with its long-term usage.
Jeremy Y. Ng   +2 more
doaj   +1 more source

Open source production of encyclopedias: editorial policies at the intersection of organizational and epistemological trust [PDF]

open access: yes, 2012
The ideas behind open source software are currently applied to the production of encyclopedias. A sample of six English text-based, neutral-point-of-view, online encyclopedias of the kind are identified: h2g2, Wikipedia, Scholarpedia, Encyclopedia of ...
de Laat, Paul B., de Laat, P.B.
core   +1 more source

Noninvasive Characterization of Tumor Heterogeneity in HNSCC: From Clinical Utility to Biological Correlates

open access: yesAdvanced Science, EarlyView.
This study establishes a CT‐based radiomics framework to quantify intratumoral heterogeneity (ITH) in HNSCC. Using unsupervised clustering, tumor ROIs and VOIs are analyzed to calculate 2D/3D ITH scores. The score shows strong predictive value for prognosis and immunotherapy response, and is associated with tumor metabolism and immune microenvironment,
Xinwei Chen   +15 more
wiley   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu   +11 more
wiley   +1 more source

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