Results 61 to 70 of about 19,286 (280)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Media conglomerates [PDF]

, 2015
Literature review on international communciation and media ...
Biltereyst, Daniël
core   +1 more source

Offline and online data: on upgrading functional information to knowledge [PDF]

, 2012
This paper addresses the problem of upgrading functional information to knowledge. Functional information is defined as syntactically well-formed, meaningful and collectively opaque data.
Primiero, Giuseppe
core   +2 more sources

Multi‐Tissue Genetic Regulation of RNA Editing in Pigs

Advanced Science, EarlyView.
This study presents the first multi‐tissue map of RNA editing and its genetic regulation in pigs. By integrating RNA editing profiles, edQTL mapping, GWAS, and cross‐species comparisons, this work establishes RNA editing as a distinct regulatory layer linking genetic variation to complex traits, highlighting its functional and evolutionary significance.
Xiangchun Pan, Wentao Gong, Xiaodian Cai, Jinyan Teng, Jiali Cai, Haonan Zeng, Wondossen Ayalew, Qingpeng Shen, Zhanming Zhong, Yifei Wang, Wenjing Zhang, Yuhan Tian, Dantong Xu, Yahui Gao, Hongwei Yin, Yuebo Zhang, Jiahui Hou, Tianru Zhou, Jiaqi Li, Lingzhao Fang, Xiaolong Yuan, Zhe Zhang   +21 more
wiley   +1 more source

Encyclopedia of Modern Ukraine in the challenges of today

Енциклопедичний Вісник України, 2019
The article is devoted to the 5th anniversary of the electronic version of the Encyclopedia of Modern Ukraine (EMU) on the Internet (website: esu.com.ua).
Mykola Zhelezniak
doaj   +1 more source

Architecture: a guide to finding information [PDF]

, 2015
A guide to finding books and journals in the ...
Geoff Morgan
core  

Media education technologies in developing students' professional competence [PDF]

, 2010
While pervasive healthcare systems bear the potential to provide patients with a new quality of medical homecare, the complexity of such systems raises fundamental questions of behavior, communication and technology acceptance.
Biletskyi, V. S., Onkovych, H., Yanyshyn, O.   +2 more
core   +1 more source

Ontology Learning from Online Chinese Encyclopedias

AASRI Procedia, 2012
Abstract An ontology is very important in describing and sharing knowledge of a domain. This paper proposes a method to automatically generate domain ontologies from Chinese encyclopedias on the web. First, we use the terms appears in category systems of encyclopedias as concepts and resolute synonyms, then derive an original taxonomy from Chinese ...
Li, Yingna, Ruan, Tong, Hu, Fanghuai
openaire   +1 more source

CRISPR‐Cas9‐Loaded Theranostic Liposomes for Enhancing Radiosensitization of Prostate Cancer through POLD4 Gene Editing under Real‐Time MRI Monitoring

Advanced Science, EarlyView.
This study identifies POLD4 as a potential prostate cancer radiosensitization target through transcriptome sequencing. By encapsulating POLD4‐targeted CRISPR/Cas9 plasmids and USPIONs in cationic liposomes, an MRI‐monitored gene‐editing platform is established.
Xuhui Fan, Ruru Zhang, Linjun Yang, Shixiong Chen, Meijuan He, Yongqiang Wang, Linjie Huang, Jianfeng Zeng, Shuwang Wu, Mingyuan Gao, Han Wang   +10 more
wiley   +1 more source