Advanced Science, EarlyView.Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao +9 more
wiley +1 more source
Online Communication Attitudes and Video Game Co-Play in Older Adults: Cross-Sectional Mediation Study. [PDF]
JMIR AgingTseng JT.
europepmc +1 more source
Performance–Complexity Trade‐Offs in Battery Lifetime Prediction with Task‐Aware Transformers
Advanced Science, EarlyView.FAST‐BatPro integrates convolutional feature extraction, flash Attention, and sparse attention for efficient battery lifetime prediction. Using limited early‐cycle data across multiple chemistries and operating conditions, it achieves robust accuracy while reducing inference latency, computational cost, and energy consumption.
Jingyuan Zhao +9 more
wiley +1 more source
Immersive experience of online gaming among Chinese college students: the enhanced effect of sleep deprivation on emotion regulation and problematic gaming within the I-PACE model. [PDF]
BMC PsycholZhao X, Wang C, Liu W.
europepmc +1 more source
Sustainable Materials Design With Multi‐Modal Artificial Intelligence
Advanced Science, EarlyView.Critical mineral scarcity, high embodied carbon, and persistent pollution from materials processing intensify the need for sustainable materials design. This review frames the problem as multi‐objective optimization under heterogeneous, high‐dimensional evidence and highlights multi‐modal AI as an enabling pathway.
Tianyi Xu +8 more
wiley +1 more source
FoMO and cyberstalking in adults: the mediating roles of early maladaptive schemas and phubbing. [PDF]
Front PsycholKoçak L.
europepmc +1 more source
The Possibility of Online Mediation under the Hungarian Mediation Act
Masaryk University Journal of Law and Technology, 2008 The first question which has to be discussed is the definition of online dispute resolution and, the definition of online mediation, and we would like to show the features (advantages and disadvantages) of online mediation. The presentation focuses on the Hungarian legal background.
openaire +1 more source
Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices
Advanced Science, EarlyView.Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen +9 more
wiley +1 more source
Night running and internet addiction among university students: a serial mediation model of stress/anxiety and rumination. [PDF]
Front PsycholLiang S, Islam KMS, Wu J, Ye Z, Gao T.
europepmc +1 more source
Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
Advanced Science, EarlyView.This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source