Results 31 to 40 of about 8,908,516 (251)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Motivation of Students’ Persistency for Online Learning under Multiple Mediation Effect [PDF]
This paper probed deep into the motivation of students’ persistency for online learning from the perspective of user experience of online learning platforms, in the purpose of increasing user stickiness and formulating effective operation strategies in a
Wang, Changtian +6 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Early adolescent children engage in Internet-based online activities on smartphones and social media, which may result in online risks, including sexual risks.
Kendra Allison, Robin M. Dawson
doaj +1 more source
The COVID-19 lockdown saw an increased reliance on digital technology for children, which might have called for changes in parental mediation practices.
Beatrice Sciacca +5 more
doaj
Background The internet has become the most widely used medium among teenagers, who spend much of their time online, which raises parental concerns. Notwithstanding teens’ increased internet use and exposure to online risks, little is yet known about ...
Sarosh Iqbal +2 more
doaj +1 more source
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
This paper applies mechanism design to conflict resolution. We determine when and how unmediated communication and mediation reduce the ex ante probability of conflict in a game with asymmetric information.
Hörner, Johannes +6 more
core +2 more sources
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Modeling adolescent online risk-taking through digital literacy and parental mediation in Indonesia
Indonesia’s rapidly expanding digital ecosystem poses significant challenges for adolescent online safety, particularly within contexts where family guidance may intersect with community-based norms and governance structures.
Lidia Sandra
doaj +1 more source

