Results 121 to 130 of about 4,496,566 (351)

Childhood adversities and adult psychopathology in the National Comorbidity Survey Replication (NCS-R) I: Associations with first onset of DSM-IV disorders

Archives of General Psychiatry, 2010
Context Although significant associations of childhood adversities (CAs) with adult mental disorders have been documented consistently in epidemiological surveys, these studies generally have examined only one CA per study.
J. Green, K. McLaughlin, P. Berglund, M. Gruber, N. Sampson, A. Zaslavsky, R. Kessler   +6 more
semanticscholar   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Association of older paternal age with earlier onset among co-affected schizophrenia sib-pairs

, 2017
Background. Advanced paternal age is associated with increased risk of schizophrenia. This study aimed to explore whether older paternal age is associated with earlier onset among co-affected schizophrenia sib-pairs with the same familial predisposition.
Wang, S. H.;Liu, C. M.;Hwu, H. G.;Hsiao, C. K.;Chen, W. J., 劉智民;陳為堅;胡海國;蕭朱杏   +1 more
core   +1 more source

Early and Late Onset Seizures After Cerebrovascular Disease [PDF]

, 2015
Objectives:This study aimed to compare seizure types, clinical and demographic features, treatment response and prognosis among patients with early and late onset post-stroke seizures.Methods:A retrospective evaluation was made of the data of 46 patients
Sevda Yıldız GÖKÇEER, Nihal IŞIK, Gokceer, Sevda Yildiz, Isik, Nihal, İlknur AYDIN CANTÜRK, Adile ÖZKAN, Fatma CANDAN, Candan, Fatma, Canturk, Ilknur Aydin, Ozkan, Adile   +9 more
core   +1 more source

Characterizing rainfall patterns and dynamics in the Little Ruaha catchment, southern Tanzania

Frontiers in Water
Water resources in many regions are increasingly under pressure due to population growth, agricultural expansion, and climate variability, which presents significant challenges in maintaining sustainable water supplies.
Florence H. Mahay, Patrick C. Valimba, Madaka H. Tumbo, Fides J. Izdori, Mohamed F. Mwabumba, Winfred B. Mbungu   +5 more
doaj   +1 more source

Onset of Convection in an Inclined Anisotropic Porous Layer with Internal Heat Generation

Fluids, 2019
The onset of convection in an inclined porous layer which is heated internally by a uniform distribution of heat sources is considered. We investigate the combined effects of inclination, anisotropy and internal heat generation on the linear instability ...
Leiv Storesletten, D. Andrew S. Rees
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Applying the PR-EOS to Predict the Onset of Asphaltene Precipitation from n-Alkane Diluted Bitumens [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2007
Asphaltenes are the n-pentane or n-heptane insoluble fractions of crude oil that remain in solution under reservoir temperature and pressure conditions.
Samaneh Soroush, Mohsen Vafaie Sefti, Rahim Masoudi   +2 more
doaj  

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Total neoadjuvant therapy in early-onset versus average-onset locally advanced rectal cancer: patient characteristics and tolerance of therapy☆

ESMO Gastrointestinal Oncology
Background: Patients with early-onset (EO, age
M.L. Conces, N. Tursun, I. Ozgur, S. Yilmaz, D. Elamin, S. Patil, Y. Bouferraa, E. Gorgun, D. Liska, E. Weinstein, S.D. Kamath, S.R. Steele, A.A. Khorana, B. Laderian, T.T. Jayakrishnan, K.G. Nair, S.R. Amarnath, E.H. Balagamwala, B.N. Estfan, H. Kessler, M.J. McNamara, M.A. Shapiro, M.A. Valente, S.S. Krishnamurthi   +23 more
doaj   +1 more source