Results 171 to 180 of about 398,735 (283)

Chiral Nanoparticles Suppress Inflammatory Infiltration to Promote Extracellular Matrix Remodeling for Ectopia Lentis Therapy

Advanced Science, EarlyView.
L‐cysteine‐configured chiral polyurethane nanoparticles suppress ocular inflammation and reduce extracellular matrix (ECM) degradation in ectopia lentis by regulating macrophages polarization and inhibiting nuclear factor kappa B signaling pathway. By promoting zonular fiber‐associated protein restoration and tissue repair, this minimally invasive ...
Yinuo Wen, Yan Yang, Haihan Gao, Yan Liu, Xinyue Wang, Linghao Song, Ruohong Li, Ao Miao, Jie Xu, Zhennan Zhao, Dan Li, Shenjie Peng, Linzhao Li, Min Zhang, Yonghang Liu, Liren Wang, Tianhui Chen, Yongxiang Jiang   +17 more
wiley   +1 more source

Kojève's silence: science and the end of history. [PDF]

Cont Philos Rev
van Gemert T.
europepmc   +1 more source

Two Foundations of Unity: A Comparative Study of "The Framework of Everything" and Base Ontology (A = A + (–A₀))

This paper presents a comparative analysis of two ambitious frameworks for scientific unification: The Framework of Everything (FOE) by Russell R. Smith, and Base Ontology (A = A + (–A₀)) by Andrew Grand. FOE constructs a formal logical architecture aimed at eliminating paradoxes from physical theory, while Base Ontology accepts contradiction as a ...
openaire   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Anniversary bulletin, 1943-1993: Unity Movement 50th year of struggle-and the struggle continues

The Unity Movement was established in 1943 after long and hard struggles of the disfranchised oppressed people in South Africa against foreign domination by first the Dutch and then the British ruling classes. The Non-European Unity Movement (NEUM) as it
New Unity Movement
core  

Attribution of consciousness to non-human animals: insights from AI and multidimensional frameworks. [PDF]

Front Psychol
Chiarella SG, Laurenzi M, D'Onofrio M, Gallagher S, Raffone A.   +4 more
europepmc   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Reclaiming human dignity: a critical review of contemporary theories in light of ontological foundations. [PDF]

Med Health Care Philos
Frantz P, Rego F, Barbas S.
europepmc   +1 more source

ML Workflows for Screening Degradation‐Relevant Properties of Forever Chemicals

Advanced Science, EarlyView.
The environmental persistence of per‐ and polyfluoroalkyl substances (PFAS) necessitates efficient remediation strategies. This study presents physics‐informed machine learning workflows that accurately predict critical degradation properties, including bond dissociation energies and polarizability.
Pranoy Ray, Andrew R. Castillo, Manoj Kolel‐Veetil, Surya R. Kalidindi   +3 more
wiley   +1 more source

Unity játékfejlesztés

A szakdolgozat egy 3D parkour játék fejlesztési folyamatát mutatja be, melyet a Unity játékmotor segítségével készitünk el. A játék célja, hogy a játékosoknak egyedi, kihívásokkal teli élményt nyújtson.
Takács, Péter Imre
core