Results 161 to 170 of about 415,005 (284)

The Landscape of Long Non‐Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit

Advanced Science, EarlyView.
This study reveals that long non‐coding RNAs represent important regulatory components underlying pear domestication and improvement. Integrative multi‐omics analyses identify selected lncRNAs associated with fruit traits, while functional validation uncovers a lignin‐related lncRNA, lncRNA‐pys, that promotes lignin accumulation.
Bobo Song, Peilin Han, Jiaming Li, Xiaolong Li, Xiang Zhang, Jing Fan, Dongliang Liu, Jianfa Cai, Lingchao Zhang, Jun Wu   +9 more
wiley   +1 more source

Human Dignity and the Metaphysical Crisis in Postmodern Ethics. [PDF]

Linacre Q
Frantz P, Rego F, Barbas S.
europepmc   +1 more source

Draft Agreement on Co-operation Between the Organization of African Unity (OAU) and the International Fund for Agricultural Development (IFAD)

, 1982
Council of Ministers Thirty-eighth Ordinary Session Addis Ababa, Ethiopia 22 February - 1 March 1982This is a draft report of co-operation agreement between the Organization of African Unity (OAU) and the International Fund for Agricultural Development (
Organization of African Unity
core  

Genome‐Wide and Multi‐Omics Analysis Identified DNA‐Interacting Circular RNA circFOXK2 as MLL1 Regulator for Histone H3K4 Methylation in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Circular RNA circFOXK2 is frequently upregulated in pancreatic ductal adenocarcinoma to promote tumor heterogeneity, growth, and metastasis. Through circRNA‐DNA interaction at different genomic locations, circFOXK2 removes the PPIE inhibitory effects on MLL1 for gene‐activating H3K4 methylation of the oncogenes.
Chi Hin Wong, Jessica Jazmin Peña‐Paladines, Sum Yin Valerie Leung, Ka‐Fai To, Kenneth Siu Ho Chok, Yangchao Chen   +5 more
wiley   +1 more source

From structure to experience: a Spinozist framework for consciousness rooted in critical brain dynamics. [PDF]

Neurosci Conscious
Algom I, Nachshoni Y, Salti M, Shriki O.
europepmc   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

The Onto-Rhythmic Self: An Ontological Reframing of Subjectivity. [PDF]

Integr Psychol Behav Sci
Rahimi MD.
europepmc   +1 more source

The polyyphony in the work of Camus : from ontological unity to discursive rupture

, 2008
D'une confidence fortuite à la polyphonie bakhtinienneL'origine de ce projet de thèse est une histoire familiale. J'étais étudiante en lettres lorsque ma mère, au détour d'une conversation, me confie que Camus a écrit sur mon grand-père et qu'on peut trouver ces documents dans les Cahiers Albert Camus.
openaire   +1 more source

USP30‐Mediated Deubiquitination of PEX5 Suppresses Pexophagy to Drive Tubular Injury in Diabetic Kidney Disease

Advanced Science, EarlyView.
USP30 accumulation in diabetic renal tubular epithelial cells deubiquitinates PEX5, suppresses pexophagy, and drives dysfunctional peroxisome accumulation and tubular injury. USP30 depletion restores PEX5 ubiquitination and pexophagy, improves peroxisomal function, and alleviates tubular damage, highlighting USP30 as a therapeutic target in diabetic ...
Jia Li, Chaoyang Hua, Guangpu Li, Furong Zhai, Jingjing Ren, Shaokang Pan, Qi Feng, Jianguo Wen, Dongwei Liu, Zhangsuo Liu, Jiayu Duan   +10 more
wiley   +1 more source

Madpessimism: A Manifesto. [PDF]

Nurs Inq
Adam S.
europepmc   +1 more source